ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	113/618	423/7206	1.97666116914e-30
ko05033	Nicotine addiction	38/618	56/7206	4.87392283239e-28
ko04724	Glutamatergic synapse	60/618	152/7206	5.14460886967e-26
ko04727	GABAergic synapse	44/618	110/7206	1.36544352842e-19
ko05032	Morphine addiction	44/618	110/7206	1.36544352842e-19
ko04723	Retrograde endocannabinoid signaling	52/618	175/7206	2.33243159827e-16
ko04721	Synaptic vesicle cycle	33/618	80/7206	1.86526254209e-15
ko04728	Dopaminergic synapse	52/618	185/7206	3.07956586576e-15
ko04713	Circadian entrainment	43/618	136/7206	8.75195193974e-15
ko04024	cAMP signaling pathway	62/618	279/7206	8.71711033222e-13
ko04742	Taste transduction	24/618	61/7206	4.61715729282e-11
ko05030	Cocaine addiction	25/618	73/7206	6.00122376288e-10
ko04261	Adrenergic signaling in cardiomyocytes	46/618	205/7206	6.44650508991e-10
ko04725	Cholinergic synapse	38/618	160/7206	3.92692879244e-09
ko04911	Insulin secretion	31/618	117/7206	6.89356138204e-09
ko05014	Amyotrophic lateral sclerosis (ALS)	23/618	74/7206	2.43886636038e-08
ko04726	Serotonergic synapse	33/618	137/7206	2.93574473934e-08
ko05031	Amphetamine addiction	25/618	91/7206	9.35421462304e-08
ko04514	Cell adhesion molecules (CAMs)	31/618	130/7206	9.93968820614e-08
ko04921	Oxytocin signaling pathway	42/618	209/7206	1.14455650715e-07
ko04010	MAPK signaling pathway	56/618	321/7206	1.91206353958e-07
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	20/618	79/7206	7.18295765832e-06
ko04020	Calcium signaling pathway	45/618	265/7206	8.78572429808e-06
ko04970	Salivary secretion	22/618	95/7206	1.20267006506e-05
ko04720	Long-term potentiation	22/618	99/7206	2.40867416457e-05
ko04360	Axon guidance	39/618	233/7206	3.98258920646e-05
ko03040	Spliceosome	1/618	145/7206	6.13881819207e-05
ko04260	Cardiac muscle contraction	21/618	98/7206	6.49787680982e-05
ko04915	Estrogen signaling pathway	25/618	131/7206	0.00011003399299
ko04972	Pancreatic secretion	22/618	111/7206	0.000193485192416
ko04730	Long-term depression	17/618	78/7206	0.000256531379422
ko04060	Cytokine-cytokine receptor interaction	4/618	191/7206	0.000328899007154
ko04072	Phospholipase D signaling pathway	32/618	197/7206	0.00039773835812
ko05414	Dilated cardiomyopathy	21/618	112/7206	0.000505252042671
ko05203	Viral carcinogenesis	9/618	277/7206	0.000602746231582
ko04120	Ubiquitin mediated proteolysis	2/618	138/7206	0.000619297890401
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/618	14/7206	0.000640210126869
ko05205	Proteoglycans in cancer	9/618	271/7206	0.000802324154279
ko00240	Pyrimidine metabolism	1/618	110/7206	0.000913742682039
ko04022	cGMP-PKG signaling pathway	33/618	216/7206	0.00114592894012
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/618	59/7206	0.00120080317504
ko04971	Gastric acid secretion	18/618	98/7206	0.00162700758303
ko05322	Systemic lupus erythematosus	3/618	151/7206	0.00167833668457
ko04930	Type II diabetes mellitus	12/618	54/7206	0.00169844162392
ko03013	RNA transport	4/618	166/7206	0.0017999982092
ko05168	Herpes simplex infection	5/618	182/7206	0.00192600728966
ko04540	Gap junction	22/618	128/7206	0.00198810109176
ko04621	NOD-like receptor signaling pathway	4/618	157/7206	0.0035252047996
ko04925	Aldosterone synthesis and secretion	18/618	105/7206	0.00411715213435
ko05410	Hypertrophic cardiomyopathy (HCM)	17/618	100/7206	0.00586062069644
ko01200	Carbon metabolism	3/618	128/7206	0.00630183022702
ko05164	Influenza A	5/618	167/7206	0.00713078708029
ko03018	RNA degradation	1/618	84/7206	0.0093146075588
ko04964	Proximal tubule bicarbonate reclamation	7/618	29/7206	0.00967999516012
ko04612	Antigen processing and presentation	1/618	77/7206	0.0133065932685
ko03008	Ribosome biogenesis in eukaryotes	1/618	79/7206	0.0135232886641
ko04141	Protein processing in endoplasmic reticulum	7/618	184/7206	0.01576240152
ko00310	Lysine degradation	1/618	73/7206	0.0194299107281
ko04966	Collecting duct acid secretion	6/618	26/7206	0.0202315645432
ko04014	Ras signaling pathway	35/618	279/7206	0.0213866393321
ko04140	Autophagy - animal	6/618	164/7206	0.0226662222221
ko04973	Carbohydrate digestion and absorption	8/618	42/7206	0.0242562127117
ko04962	Vasopressin-regulated water reabsorption	10/618	58/7206	0.0296384096412
ko05162	Measles	4/618	120/7206	0.0326133617704
ko04350	TGF-beta signaling pathway	3/618	103/7206	0.0330298486374
ko04146	Peroxisome	2/618	89/7206	0.0331255829436
ko02024	Quorum sensing	4/618	15/7206	0.0340695621827
ko04015	Rap1 signaling pathway	34/618	278/7206	0.036935977343
ko00561	Glycerolipid metabolism	1/618	63/7206	0.0409331534634
ko04640	Hematopoietic cell lineage	1/618	64/7206	0.0411633094167
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/618	182/7206	0.0430963932254
ko04150	mTOR signaling pathway	8/618	184/7206	0.0438077701171
ko04138	Autophagy - yeast	2/618	81/7206	0.0449916609083
ko04137	Mitophagy - animal	2/618	82/7206	0.0452293872569
ko00564	Glycerophospholipid metabolism	3/618	99/7206	0.0455828259463
ko05146	Amoebiasis	3/618	99/7206	0.0455828259463
ko04750	Inflammatory mediator regulation of TRP channels	17/618	122/7206	0.0477164122252
ko05210	Colorectal cancer	13/618	86/7206	0.0486373745849
ko04924	Renin secretion	13/618	86/7206	0.0486373745849