ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	64/766	152/7206	3.02220088565e-24
ko05033	Nicotine addiction	37/766	56/7206	2.54376608919e-23
ko04080	Neuroactive ligand-receptor interaction	112/766	423/7206	2.22542351191e-21
ko04721	Synaptic vesicle cycle	41/766	80/7206	8.33327184787e-20
ko05032	Morphine addiction	48/766	110/7206	3.19873155192e-19
ko04728	Dopaminergic synapse	64/766	185/7206	7.27522431587e-19
ko04727	GABAergic synapse	47/766	110/7206	2.17574027554e-18
ko04713	Circadian entrainment	49/766	136/7206	1.68065897523e-15
ko04723	Retrograde endocannabinoid signaling	56/766	175/7206	6.29837526513e-15
ko04725	Cholinergic synapse	52/766	160/7206	2.99734000735e-14
ko04024	cAMP signaling pathway	70/766	279/7206	2.43047192758e-12
ko04911	Insulin secretion	39/766	117/7206	2.24730285847e-11
ko04726	Serotonergic synapse	39/766	137/7206	4.20929320682e-09
ko04921	Oxytocin signaling pathway	48/766	209/7206	1.52871112366e-07
ko04744	Phototransduction	16/766	36/7206	2.14778490148e-07
ko04261	Adrenergic signaling in cardiomyocytes	46/766	205/7206	7.20504415605e-07
ko05030	Cocaine addiction	23/766	73/7206	9.41444628651e-07
ko05031	Amphetamine addiction	26/766	91/7206	1.53569093832e-06
ko03040	Spliceosome	1/766	145/7206	2.0321567688e-06
ko04970	Salivary secretion	26/766	95/7206	3.7302451982e-06
ko04514	Cell adhesion molecules (CAMs)	32/766	130/7206	4.03646859473e-06
ko04742	Taste transduction	19/766	61/7206	1.00167216232e-05
ko04360	Axon guidance	47/766	233/7206	1.14765314445e-05
ko04972	Pancreatic secretion	28/766	111/7206	1.23871578344e-05
ko04966	Collecting duct acid secretion	11/766	26/7206	3.13491104506e-05
ko04010	MAPK signaling pathway	58/766	321/7206	3.8913707468e-05
ko04720	Long-term potentiation	25/766	99/7206	3.98845748164e-05
ko04020	Calcium signaling pathway	50/766	265/7206	4.07533827531e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	20/766	74/7206	5.93653799813e-05
ko05203	Viral carcinogenesis	11/766	277/7206	6.08479903751e-05
ko03013	RNA transport	4/766	166/7206	0.000100914898302
ko05164	Influenza A	4/766	167/7206	0.000103173456237
ko04730	Long-term depression	20/766	78/7206	0.000132257768166
ko04120	Ubiquitin mediated proteolysis	3/766	138/7206	0.000237888593828
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/766	14/7206	0.000261696296817
ko05205	Proteoglycans in cancer	12/766	271/7206	0.000271737468085
ko05168	Herpes simplex infection	6/766	182/7206	0.000358597485488
ko05322	Systemic lupus erythematosus	4/766	151/7206	0.00041932863159
ko04260	Cardiac muscle contraction	22/766	98/7206	0.000683762023337
ko04060	Cytokine-cytokine receptor interaction	7/766	191/7206	0.000739758426707
ko04141	Protein processing in endoplasmic reticulum	7/766	184/7206	0.000982778751123
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/766	79/7206	0.0014245931657
ko04022	cGMP-PKG signaling pathway	38/766	216/7206	0.0015687610659
ko04964	Proximal tubule bicarbonate reclamation	9/766	29/7206	0.00232439352628
ko05110	Vibrio cholerae infection	15/766	63/7206	0.00282804224524
ko04621	NOD-like receptor signaling pathway	6/766	157/7206	0.00354492980907
ko04925	Aldosterone synthesis and secretion	21/766	105/7206	0.00366949247911
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/766	59/7206	0.00418769952228
ko04070	Phosphatidylinositol signaling system	22/766	112/7206	0.00464930623551
ko05162	Measles	4/766	120/7206	0.00640966839377
ko04014	Ras signaling pathway	44/766	279/7206	0.00715796961742
ko04971	Gastric acid secretion	19/766	98/7206	0.00788795205667
ko05161	Hepatitis B	8/766	173/7206	0.0081207312618
ko05169	Epstein-Barr virus infection	11/766	206/7206	0.0110694802577
ko04064	NF-kappa B signaling pathway	3/766	96/7206	0.0115657734928
ko04640	Hematopoietic cell lineage	1/766	64/7206	0.0126603846547
ko04540	Gap junction	23/766	128/7206	0.0127574611799
ko04217	Necroptosis	9/766	178/7206	0.0130849659592
ko04072	Phospholipase D signaling pathway	32/766	197/7206	0.0134144413587
ko04140	Autophagy - animal	8/766	164/7206	0.0140984203845
ko04915	Estrogen signaling pathway	23/766	131/7206	0.0142638847876
ko04391	Hippo signaling pathway - fly	17/766	90/7206	0.01548074197
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/766	15/7206	0.0162196338242
ko00330	Arginine and proline metabolism	1/766	61/7206	0.0189805436927
ko05414	Dilated cardiomyopathy	20/766	112/7206	0.0191763643374
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/766	182/7206	0.0201647194604
ko00310	Lysine degradation	2/766	73/7206	0.0212885470067
ko04924	Renin secretion	16/766	86/7206	0.0216204064181
ko05140	Leishmaniasis	2/766	75/7206	0.0217400849825
ko04146	Peroxisome	3/766	89/7206	0.022830907667
ko05120	Epithelial cell signaling in Helicobacter pylori infection	17/766	92/7206	0.0246526800246
ko00480	Glutathione metabolism	1/766	55/7206	0.0266550547949
ko00280	Valine, leucine and isoleucine degradation	1/766	54/7206	0.0266652513715
ko00512	Mucin type O-glycan biosynthesis	7/766	29/7206	0.0289031943125
ko03018	RNA degradation	3/766	84/7206	0.0314105343333
ko05166	HTLV-I infection	20/766	292/7206	0.0325103242303
ko00590	Arachidonic acid metabolism	1/766	52/7206	0.0392831362642
ko00240	Pyrimidine metabolism	5/766	110/7206	0.0407322211693
ko05034	Alcoholism	35/766	238/7206	0.042110740873
ko04630	Jak-STAT signaling pathway	7/766	132/7206	0.0451649003641
ko04371	Apelin signaling pathway	27/766	177/7206	0.0480895214307