ko pathway ratio_in_study ratio_in_pop p_value ko00120 Primary bile acid biosynthesis 9/429 20/7206 8.06143701623e-07 ko04137 Mitophagy - animal 16/429 82/7206 2.05655347418e-05 ko04060 Cytokine-cytokine receptor interaction 26/429 191/7206 6.47267284318e-05 ko00350 Tyrosine metabolism 9/429 33/7206 9.23351300441e-05 ko04380 Osteoclast differentiation 20/429 134/7206 0.000116105380324 ko00051 Fructose and mannose metabolism 10/429 42/7206 0.000132114904926 ko04146 Peroxisome 15/429 89/7206 0.000212677402232 ko04621 NOD-like receptor signaling pathway 21/429 157/7206 0.000436389296031 ko04710 Circadian rhythm 9/429 43/7206 0.000793514788755 ko00071 Fatty acid degradation 9/429 45/7206 0.00112166288145 ko05140 Leishmaniasis 12/429 75/7206 0.00144209114153 ko05034 Alcoholism 4/429 238/7206 0.00196768243956 ko04110 Cell cycle 1/429 145/7206 0.00220594530294 ko04610 Complement and coagulation cascades 12/429 79/7206 0.00227885186003 ko04630 Jak-STAT signaling pathway 17/429 132/7206 0.00231061797257 ko05164 Influenza A 20/429 167/7206 0.00245087385593 ko00360 Phenylalanine metabolism 5/429 17/7206 0.00248709557353 ko00010 Glycolysis / Gluconeogenesis 11/429 74/7206 0.00406997102258 ko00592 alpha-Linolenic acid metabolism 5/429 19/7206 0.00423408179709 ko03013 RNA transport 2/429 166/7206 0.00423982947797 ko05144 Malaria 8/429 45/7206 0.00454050026538 ko05150 Staphylococcus aureus infection 7/429 36/7206 0.00467126014967 ko05162 Measles 15/429 120/7206 0.00544813912975 ko03010 Ribosome 1/429 129/7206 0.00713825848436 ko03320 PPAR signaling pathway 10/429 69/7206 0.0072447181842 ko04611 Platelet activation 18/429 163/7206 0.0106887820386 ko05145 Toxoplasmosis 15/429 126/7206 0.0113499591117 ko03040 Spliceosome 2/429 145/7206 0.0121454946317 ko04270 Vascular smooth muscle contraction 17/429 154/7206 0.014096936475 ko04932 Non-alcoholic fatty liver disease (NAFLD) 19/429 182/7206 0.0159609112043 ko05321 Inflammatory bowel disease (IBD) 8/429 56/7206 0.0169340894366 ko00950 Isoquinoline alkaloid biosynthesis 3/429 10/7206 0.0183639403735 ko05152 Tuberculosis 19/429 187/7206 0.018652335867 ko04662 B cell receptor signaling pathway 11/429 88/7206 0.0191652576262 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/429 4/7206 0.0195792124344 ko00643 Styrene degradation 2/429 4/7206 0.0195792124344 ko00710 Carbon fixation in photosynthetic organisms 5/429 27/7206 0.0198691167066 ko04672 Intestinal immune network for IgA production 6/429 37/7206 0.020738715554 ko00982 Drug metabolism - cytochrome P450 6/429 37/7206 0.020738715554 ko01200 Carbon metabolism 14/429 128/7206 0.0229048831854 ko05167 Kaposi's sarcoma-associated herpesvirus infection 19/429 191/7206 0.0280857450668 ko04068 FoxO signaling pathway 17/429 167/7206 0.0293701636422 ko04658 Th1 and Th2 cell differentiation 11/429 96/7206 0.0293911188441 ko04064 NF-kappa B signaling pathway 11/429 96/7206 0.0293911188441 ko04622 RIG-I-like receptor signaling pathway 8/429 62/7206 0.0296242670901 ko05340 Primary immunodeficiency 5/429 30/7206 0.0303255382903 ko00590 Arachidonic acid metabolism 7/429 52/7206 0.0331757401874 ko01230 Biosynthesis of amino acids 10/429 85/7206 0.0340188902232 ko04659 Th17 cell differentiation 12/429 106/7206 0.0342385876497 ko05224 Breast cancer 4/429 174/7206 0.0344106586021 ko04136 Autophagy - other 5/429 31/7206 0.0344524105228 ko04540 Gap junction 2/429 128/7206 0.0350588295199 ko05322 Systemic lupus erythematosus 3/429 151/7206 0.0352154150064 ko00983 Drug metabolism - other enzymes 6/429 42/7206 0.0365185850475 ko05133 Pertussis 10/429 87/7206 0.0377728180677 ko04711 Circadian rhythm - fly 3/429 13/7206 0.0383299066216 ko04933 AGE-RAGE signaling pathway in diabetic complications 14/429 135/7206 0.0404958508208 ko00052 Galactose metabolism 5/429 33/7206 0.0437046843576 ko03015 mRNA surveillance pathway 1/429 93/7206 0.0439139368924 ko00362 Benzoate degradation 2/429 6/7206 0.0452032384843 ko04650 Natural killer cell mediated cytotoxicity 11/429 97/7206 0.0466200217971 ko05418 Fluid shear stress and atherosclerosis 17/429 173/7206 0.0481962978246