ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	39/640	56/7206	7.64727988684e-29
ko04724	Glutamatergic synapse	63/640	152/7206	7.67813540942e-28
ko04080	Neuroactive ligand-receptor interaction	108/640	423/7206	7.05725220713e-26
ko05032	Morphine addiction	47/640	110/7206	1.15262391907e-21
ko04727	GABAergic synapse	46/640	110/7206	9.31614645614e-21
ko04723	Retrograde endocannabinoid signaling	57/640	175/7206	3.21258799441e-19
ko04713	Circadian entrainment	49/640	136/7206	9.56811896627e-19
ko04728	Dopaminergic synapse	57/640	185/7206	6.13534797594e-18
ko04725	Cholinergic synapse	46/640	160/7206	1.93118858186e-13
ko04911	Insulin secretion	38/640	117/7206	3.88596722758e-13
ko04024	cAMP signaling pathway	63/640	279/7206	1.29001579668e-12
ko04721	Synaptic vesicle cycle	28/640	80/7206	6.96988441444e-11
ko05031	Amphetamine addiction	30/640	91/7206	8.06332374335e-11
ko04261	Adrenergic signaling in cardiomyocytes	47/640	205/7206	6.29778624199e-10
ko05030	Cocaine addiction	25/640	73/7206	1.25588572457e-09
ko04020	Calcium signaling pathway	54/640	265/7206	3.54888930338e-09
ko04720	Long-term potentiation	29/640	99/7206	3.83135681412e-09
ko04742	Taste transduction	22/640	61/7206	4.11540636516e-09
ko04514	Cell adhesion molecules (CAMs)	31/640	130/7206	2.19635927195e-07
ko04010	MAPK signaling pathway	57/640	321/7206	3.02616225737e-07
ko04921	Oxytocin signaling pathway	42/640	209/7206	3.47981564614e-07
ko04726	Serotonergic synapse	30/640	137/7206	2.37505956973e-06
ko04925	Aldosterone synthesis and secretion	25/640	105/7206	3.39009356494e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	20/640	74/7206	4.12996015987e-06
ko05203	Viral carcinogenesis	6/640	277/7206	6.96005959581e-06
ko04072	Phospholipase D signaling pathway	37/640	197/7206	9.72492499951e-06
ko03040	Spliceosome	1/640	145/7206	4.10734018023e-05
ko04060	Cytokine-cytokine receptor interaction	3/640	191/7206	4.44461466648e-05
ko04360	Axon guidance	40/640	233/7206	5.05163702195e-05
ko04970	Salivary secretion	21/640	95/7206	6.68470799081e-05
ko04915	Estrogen signaling pathway	25/640	131/7206	0.000243448919805
ko04972	Pancreatic secretion	22/640	111/7206	0.000277709211855
ko05168	Herpes simplex infection	4/640	182/7206	0.000320489534725
ko04730	Long-term depression	17/640	78/7206	0.000388211174051
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/640	79/7206	0.000454764188607
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/640	14/7206	0.00077291687255
ko05205	Proteoglycans in cancer	10/640	271/7206	0.00101951849445
ko00515	Mannose type O-glycan biosynthesis	8/640	25/7206	0.00102251404372
ko05414	Dilated cardiomyopathy	21/640	112/7206	0.00107155117631
ko04740	Olfactory transduction	16/640	80/7206	0.0020851619951
ko00512	Mucin type O-glycan biosynthesis	8/640	29/7206	0.00295153066209
ko04022	cGMP-PKG signaling pathway	32/640	216/7206	0.00337874220434
ko05164	Influenza A	5/640	167/7206	0.00361513820558
ko00240	Pyrimidine metabolism	2/640	110/7206	0.0038026724148
ko03013	RNA transport	5/640	166/7206	0.00515666551372
ko04070	Phosphatidylinositol signaling system	19/640	112/7206	0.00627195634823
ko04971	Gastric acid secretion	17/640	98/7206	0.00640301785932
ko04014	Ras signaling pathway	38/640	279/7206	0.00700916547177
ko04350	TGF-beta signaling pathway	2/640	103/7206	0.00788116621364
ko03008	Ribosome biogenesis in eukaryotes	1/640	79/7206	0.00901749118106
ko04540	Gap junction	20/640	128/7206	0.0113085308056
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/640	182/7206	0.0117420770279
ko04744	Phototransduction	8/640	36/7206	0.0119717391798
ko05322	Systemic lupus erythematosus	5/640	151/7206	0.0129261944509
ko04612	Antigen processing and presentation	1/640	77/7206	0.013577020511
ko04110	Cell cycle	5/640	145/7206	0.0172648670456
ko04260	Cardiac muscle contraction	16/640	98/7206	0.0178795709016
ko00310	Lysine degradation	1/640	73/7206	0.020060518039
ko04621	NOD-like receptor signaling pathway	6/640	157/7206	0.0221790841189
ko04146	Peroxisome	2/640	89/7206	0.0226521513211
ko05110	Vibrio cholerae infection	11/640	63/7206	0.0243345543725
ko04150	mTOR signaling pathway	8/640	184/7206	0.0251620174506
ko04141	Protein processing in endoplasmic reticulum	8/640	184/7206	0.0251620174506
ko04930	Type II diabetes mellitus	10/640	54/7206	0.02539987643
ko04670	Leukocyte transendothelial migration	6/640	151/7206	0.0293175541393
ko03320	PPAR signaling pathway	1/640	69/7206	0.0296305639788
ko04015	Rap1 signaling pathway	35/640	278/7206	0.0312619945974
ko04137	Mitophagy - animal	2/640	82/7206	0.031715252871
ko03018	RNA degradation	2/640	84/7206	0.0319140984536
ko04371	Apelin signaling pathway	24/640	177/7206	0.0320253679254
ko04962	Vasopressin-regulated water reabsorption	10/640	58/7206	0.0344722528283
ko04722	Neurotrophin signaling pathway	22/640	160/7206	0.0345429405518
ko00330	Arginine and proline metabolism	1/640	61/7206	0.0406498188784
ko01212	Fatty acid metabolism	1/640	60/7206	0.0406741411838
ko04640	Hematopoietic cell lineage	1/640	64/7206	0.0424793607046
ko04630	Jak-STAT signaling pathway	5/640	132/7206	0.0425754987073
ko04923	Regulation of lipolysis in adipocytes	12/640	77/7206	0.0442328783498
ko05169	Epstein-Barr virus infection	10/640	206/7206	0.0453786569705
ko05034	Alcoholism	30/640	238/7206	0.0479964089496
ko05410	Hypertrophic cardiomyopathy (HCM)	15/640	100/7206	0.0482299996471