ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	84/457	423/7206	2.03207279099e-22
ko04724	Glutamatergic synapse	45/457	152/7206	2.69500428722e-19
ko04744	Phototransduction	19/457	36/7206	3.81888420895e-14
ko04713	Circadian entrainment	36/457	136/7206	5.75398682043e-14
ko05033	Nicotine addiction	23/457	56/7206	7.36966032664e-14
ko04727	GABAergic synapse	30/457	110/7206	3.36430545816e-12
ko05032	Morphine addiction	30/457	110/7206	3.36430545816e-12
ko04723	Retrograde endocannabinoid signaling	38/457	175/7206	9.14108973601e-12
ko04024	cAMP signaling pathway	50/457	279/7206	9.17484604694e-12
ko04728	Dopaminergic synapse	38/457	185/7206	5.37149356177e-11
ko04911	Insulin secretion	29/457	117/7206	1.00856780861e-10
ko04725	Cholinergic synapse	34/457	160/7206	2.21914117397e-10
ko04721	Synaptic vesicle cycle	22/457	80/7206	2.34156974406e-09
ko04720	Long-term potentiation	23/457	99/7206	3.42279786387e-08
ko05031	Amphetamine addiction	21/457	91/7206	1.54082573363e-07
ko04921	Oxytocin signaling pathway	34/457	209/7206	2.69406149277e-07
ko04726	Serotonergic synapse	26/457	137/7206	3.42839274953e-07
ko04261	Adrenergic signaling in cardiomyocytes	32/457	205/7206	1.56673829018e-06
ko04730	Long-term depression	17/457	78/7206	5.4873469607e-06
ko04970	Salivary secretion	18/457	95/7206	2.29130729378e-05
ko04971	Gastric acid secretion	18/457	98/7206	3.55173442768e-05
ko05030	Cocaine addiction	15/457	73/7206	4.10021054835e-05
ko04020	Calcium signaling pathway	34/457	265/7206	8.28686560183e-05
ko04742	Taste transduction	13/457	61/7206	8.9595135935e-05
ko04925	Aldosterone synthesis and secretion	18/457	105/7206	9.14555015983e-05
ko04060	Cytokine-cytokine receptor interaction	1/457	191/7206	0.000108082690715
ko04740	Olfactory transduction	15/457	80/7206	0.000124035802193
ko04966	Collecting duct acid secretion	8/457	26/7206	0.000139017792289
ko04550	Signaling pathways regulating pluripotency of stem cells	1/457	165/7206	0.00049394092477
ko04022	cGMP-PKG signaling pathway	27/457	216/7206	0.000577437898584
ko05014	Amyotrophic lateral sclerosis (ALS)	13/457	74/7206	0.000670291350468
ko05166	HTLV-I infection	6/457	292/7206	0.000829120485258
ko04010	MAPK signaling pathway	36/457	321/7206	0.000892891399468
ko05168	Herpes simplex infection	2/457	182/7206	0.000996894922671
ko05110	Vibrio cholerae infection	11/457	63/7206	0.00180264530643
ko05120	Epithelial cell signaling in Helicobacter pylori infection	14/457	92/7206	0.00181981040423
ko05164	Influenza A	2/457	167/7206	0.00204038786108
ko04120	Ubiquitin mediated proteolysis	1/457	138/7206	0.0022034926765
ko04745	Phototransduction - fly	8/457	38/7206	0.00222023579552
ko04972	Pancreatic secretion	16/457	111/7206	0.00224693269189
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/457	59/7206	0.00360417715094
ko04072	Phospholipase D signaling pathway	23/457	197/7206	0.00426539505673
ko00680	Methane metabolism	7/457	34/7206	0.00473948011989
ko04260	Cardiac muscle contraction	14/457	98/7206	0.00488274291395
ko05203	Viral carcinogenesis	7/457	277/7206	0.00527587855726
ko05224	Breast cancer	3/457	174/7206	0.00679378327334
ko00190	Oxidative phosphorylation	16/457	127/7206	0.00846999111734
ko03013	RNA transport	3/457	166/7206	0.00944469071131
ko04514	Cell adhesion molecules (CAMs)	16/457	130/7206	0.00967433544933
ko04978	Mineral absorption	7/457	40/7206	0.0118345271107
ko04750	Inflammatory mediator regulation of TRP channels	15/457	122/7206	0.0129142738072
ko05169	Epstein-Barr virus infection	5/457	206/7206	0.0134913605462
ko04070	Phosphatidylinositol signaling system	14/457	112/7206	0.0162528587461
ko04630	Jak-STAT signaling pathway	2/457	132/7206	0.0173174779894
ko04360	Axon guidance	24/457	233/7206	0.018963996696
ko05034	Alcoholism	24/457	238/7206	0.0210425564441
ko04350	TGF-beta signaling pathway	1/457	103/7206	0.0218891195482
ko04924	Renin secretion	11/457	86/7206	0.0228163048083
ko04626	Plant-pathogen interaction	4/457	18/7206	0.0239851597097
ko04540	Gap junction	15/457	128/7206	0.0253271242237
ko04062	Chemokine signaling pathway	21/457	201/7206	0.0259289101513
ko04371	Apelin signaling pathway	19/457	177/7206	0.026755171355
ko04722	Neurotrophin signaling pathway	17/457	160/7206	0.0319104318518
ko04964	Proximal tubule bicarbonate reclamation	5/457	29/7206	0.0336834059329
ko05010	Alzheimer's disease	20/457	202/7206	0.0403578879438
ko04960	Aldosterone-regulated sodium reabsorption	6/457	41/7206	0.0428327003415
ko04014	Ras signaling pathway	26/457	279/7206	0.0442707816444
ko00830	Retinol metabolism	6/457	42/7206	0.047411352602
ko05215	Prostate cancer	2/457	111/7206	0.047436206878
ko04940	Type I diabetes mellitus	5/457	32/7206	0.0489567081286
ko04114	Oocyte meiosis	15/457	139/7206	0.0498680142318