ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	143/842	423/7206	1.06632604999e-35
ko05033	Nicotine addiction	40/842	56/7206	1.44160188243e-25
ko04724	Glutamatergic synapse	63/842	152/7206	3.43956308767e-21
ko04721	Synaptic vesicle cycle	43/842	80/7206	3.68133577115e-20
ko05032	Morphine addiction	44/842	110/7206	1.82871303854e-14
ko04728	Dopaminergic synapse	60/842	185/7206	2.66947496601e-14
ko04727	GABAergic synapse	43/842	110/7206	9.55086593018e-14
ko04713	Circadian entrainment	45/842	136/7206	2.32746803164e-11
ko04723	Retrograde endocannabinoid signaling	51/842	175/7206	2.10658856221e-10
ko04725	Cholinergic synapse	48/842	160/7206	2.42740815332e-10
ko04742	Taste transduction	26/842	61/7206	8.58768857172e-10
ko04024	cAMP signaling pathway	67/842	279/7206	5.266396723e-09
ko04360	Axon guidance	57/842	233/7206	3.22497094719e-08
ko04726	Serotonergic synapse	39/842	137/7206	9.37409783619e-08
ko05203	Viral carcinogenesis	8/842	277/7206	1.54475042027e-07
ko04261	Adrenergic signaling in cardiomyocytes	50/842	205/7206	2.24246569942e-07
ko04921	Oxytocin signaling pathway	50/842	209/7206	4.89053328937e-07
ko03040	Spliceosome	1/842	145/7206	5.65991108136e-07
ko04911	Insulin secretion	33/842	117/7206	1.21723429867e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	24/842	74/7206	1.70426639201e-06
ko05031	Amphetamine addiction	27/842	91/7206	2.7416527727e-06
ko05030	Cocaine addiction	23/842	73/7206	4.88274790865e-06
ko04020	Calcium signaling pathway	56/842	265/7206	8.67041596496e-06
ko04060	Cytokine-cytokine receptor interaction	5/842	191/7206	9.61801182957e-06
ko04010	MAPK signaling pathway	64/842	321/7206	1.12768229593e-05
ko04514	Cell adhesion molecules (CAMs)	33/842	130/7206	1.13721889059e-05
ko05164	Influenza A	4/842	167/7206	1.50168603708e-05
ko05168	Herpes simplex infection	5/842	182/7206	1.87322053626e-05
ko03013	RNA transport	4/842	166/7206	2.22413144045e-05
ko04120	Ubiquitin mediated proteolysis	3/842	138/7206	7.45067998393e-05
ko04966	Collecting duct acid secretion	11/842	26/7206	7.61541887498e-05
ko05322	Systemic lupus erythematosus	4/842	151/7206	9.32595839375e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/842	79/7206	0.000252137652816
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/842	59/7206	0.000283295748084
ko05205	Proteoglycans in cancer	15/842	271/7206	0.00068437934704
ko04141	Protein processing in endoplasmic reticulum	8/842	184/7206	0.000684892178966
ko05169	Epstein-Barr virus infection	10/842	206/7206	0.000898045817995
ko04621	NOD-like receptor signaling pathway	6/842	157/7206	0.000930980596506
ko03008	Ribosome biogenesis in eukaryotes	1/842	79/7206	0.00116257223373
ko04720	Long-term potentiation	23/842	99/7206	0.00126199809638
ko00240	Pyrimidine metabolism	3/842	110/7206	0.00139119337106
ko04970	Salivary secretion	22/842	95/7206	0.00177716495379
ko04260	Cardiac muscle contraction	22/842	98/7206	0.00220834512393
ko04146	Peroxisome	2/842	89/7206	0.00234553841825
ko04022	cGMP-PKG signaling pathway	40/842	216/7206	0.00252441056576
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/842	14/7206	0.00327532026895
ko04730	Long-term depression	18/842	78/7206	0.00388262744628
ko05146	Amoebiasis	3/842	99/7206	0.00399202982056
ko04611	Platelet activation	8/842	163/7206	0.00425941895763
ko04964	Proximal tubule bicarbonate reclamation	9/842	29/7206	0.00445288907298
ko05110	Vibrio cholerae infection	15/842	63/7206	0.00541907176557
ko05161	Hepatitis B	9/842	173/7206	0.00546088868431
ko04640	Hematopoietic cell lineage	1/842	64/7206	0.00549413973281
ko04064	NF-kappa B signaling pathway	3/842	96/7206	0.00572998287617
ko05162	Measles	5/842	120/7206	0.00612361311795
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/842	182/7206	0.00675839320696
ko05166	HTLV-I infection	20/842	292/7206	0.00683723124313
ko04610	Complement and coagulation cascades	2/842	79/7206	0.00716170675184
ko00330	Arginine and proline metabolism	1/842	61/7206	0.00814831995869
ko04217	Necroptosis	10/842	178/7206	0.0088626892564
ko00310	Lysine degradation	2/842	73/7206	0.0100655067114
ko05140	Leishmaniasis	2/842	75/7206	0.0101890383797
ko04972	Pancreatic secretion	22/842	111/7206	0.0109129875678
ko04014	Ras signaling pathway	46/842	279/7206	0.0133955494663
ko04214	Apoptosis - fly	2/842	72/7206	0.0147872983562
ko00280	Valine, leucine and isoleucine degradation	1/842	54/7206	0.0176646982394
ko00480	Glutathione metabolism	1/842	55/7206	0.0180338913914
ko04630	Jak-STAT signaling pathway	7/842	132/7206	0.0192300689786
ko04962	Vasopressin-regulated water reabsorption	13/842	58/7206	0.0208507196854
ko05414	Dilated cardiomyopathy	21/842	112/7206	0.0253252160634
ko01200	Carbon metabolism	7/842	128/7206	0.0254508273508
ko00380	Tryptophan metabolism	1/842	50/7206	0.0258239464703
ko04140	Autophagy - animal	10/842	164/7206	0.0258337539673
ko04924	Renin secretion	17/842	86/7206	0.0267055391652
ko00590	Arachidonic acid metabolism	1/842	52/7206	0.0268804349951
ko05410	Hypertrophic cardiomyopathy (HCM)	19/842	100/7206	0.0277152838916
ko04913	Ovarian steroidogenesis	2/842	63/7206	0.0293680730628
ko00561	Glycerolipid metabolism	2/842	63/7206	0.0293680730628
ko04930	Type II diabetes mellitus	12/842	54/7206	0.0295114867705
ko01524	Platinum drug resistance	3/842	76/7206	0.0304500942067
ko04612	Antigen processing and presentation	3/842	77/7206	0.0306741773046
ko05120	Epithelial cell signaling in Helicobacter pylori infection	18/842	92/7206	0.0315211899652
ko04145	Phagosome	28/842	162/7206	0.0343057449469
ko04110	Cell cycle	9/842	145/7206	0.0362281561228
ko05215	Prostate cancer	6/842	111/7206	0.0363225907972
ko03420	Nucleotide excision repair	1/842	46/7206	0.0378069989754
ko05133	Pertussis	4/842	87/7206	0.0417717091866