ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	74/685	152/7206	1.97565728448e-36
ko05033	Nicotine addiction	43/685	56/7206	1.91545975599e-33
ko05032	Morphine addiction	56/685	110/7206	5.2064214882e-29
ko04727	GABAergic synapse	54/685	110/7206	5.52016461052e-27
ko04080	Neuroactive ligand-receptor interaction	112/685	423/7206	1.11029632544e-25
ko04723	Retrograde endocannabinoid signaling	65/685	175/7206	9.30977273781e-24
ko04713	Circadian entrainment	55/685	136/7206	2.57601654676e-22
ko04728	Dopaminergic synapse	63/685	185/7206	9.89715563861e-21
ko04024	cAMP signaling pathway	73/685	279/7206	1.54952249883e-16
ko04725	Cholinergic synapse	50/685	160/7206	6.24666181211e-15
ko04721	Synaptic vesicle cycle	32/685	80/7206	2.62419806232e-13
ko04744	Phototransduction	21/685	36/7206	3.63511221075e-13
ko04020	Calcium signaling pathway	63/685	265/7206	2.40757162104e-12
ko04911	Insulin secretion	38/685	117/7206	3.26795545138e-12
ko04726	Serotonergic synapse	41/685	137/7206	8.98984167666e-12
ko04720	Long-term potentiation	33/685	99/7206	4.07454176856e-11
ko04921	Oxytocin signaling pathway	51/685	209/7206	1.21087263847e-10
ko04261	Adrenergic signaling in cardiomyocytes	50/685	205/7206	1.89066126898e-10
ko04742	Taste transduction	24/685	61/7206	3.98290276422e-10
ko05031	Amphetamine addiction	30/685	91/7206	4.33146715579e-10
ko04925	Aldosterone synthesis and secretion	30/685	105/7206	1.94055052859e-08
ko05030	Cocaine addiction	24/685	73/7206	2.62198912317e-08
ko04010	MAPK signaling pathway	61/685	321/7206	8.39971162763e-08
ko05203	Viral carcinogenesis	5/685	277/7206	2.99032002873e-07
ko04970	Salivary secretion	25/685	95/7206	1.62770187199e-06
ko04060	Cytokine-cytokine receptor interaction	2/685	191/7206	1.98638231829e-06
ko04072	Phospholipase D signaling pathway	40/685	197/7206	2.95480941992e-06
ko03040	Spliceosome	1/685	145/7206	1.12909148819e-05
ko04740	Olfactory transduction	21/685	80/7206	1.15261353865e-05
ko04070	Phosphatidylinositol signaling system	26/685	112/7206	1.23915907184e-05
ko04514	Cell adhesion molecules (CAMs)	28/685	130/7206	2.78303627794e-05
ko04022	cGMP-PKG signaling pathway	39/685	216/7206	7.74626475213e-05
ko04730	Long-term depression	19/685	78/7206	9.11749190814e-05
ko04110	Cell cycle	2/685	145/7206	0.000138803167471
ko05014	Amyotrophic lateral sclerosis (ALS)	18/685	74/7206	0.000141574474546
ko04915	Estrogen signaling pathway	26/685	131/7206	0.000235027327371
ko04972	Pancreatic secretion	23/685	111/7206	0.000260498570248
ko04260	Cardiac muscle contraction	21/685	98/7206	0.000331963223781
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/685	79/7206	0.000340703482481
ko05168	Herpes simplex infection	5/685	182/7206	0.000492625608329
ko04745	Phototransduction - fly	11/685	38/7206	0.000578768882197
ko04350	TGF-beta signaling pathway	1/685	103/7206	0.000589554979061
ko04971	Gastric acid secretion	20/685	98/7206	0.000806047895451
ko05414	Dilated cardiomyopathy	22/685	112/7206	0.000888627417794
ko05169	Epstein-Barr virus infection	7/685	206/7206	0.00103719046729
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/685	14/7206	0.00111161092013
ko05034	Alcoholism	38/685	238/7206	0.00147007204435
ko04630	Jak-STAT signaling pathway	3/685	132/7206	0.0015226312029
ko04371	Apelin signaling pathway	30/685	177/7206	0.00161451356729
ko03013	RNA transport	5/685	166/7206	0.00185558943246
ko05164	Influenza A	5/685	167/7206	0.00187506749857
ko04014	Ras signaling pathway	42/685	279/7206	0.00238256014408
ko04621	NOD-like receptor signaling pathway	5/685	157/7206	0.00353822848841
ko05162	Measles	3/685	120/7206	0.0043218759145
ko04141	Protein processing in endoplasmic reticulum	7/685	184/7206	0.004789425282
ko05322	Systemic lupus erythematosus	5/685	151/7206	0.00485802633552
ko00562	Inositol phosphate metabolism	17/685	89/7206	0.00517909385653
ko03008	Ribosome biogenesis in eukaryotes	1/685	79/7206	0.00604047932636
ko04750	Inflammatory mediator regulation of TRP channels	21/685	122/7206	0.00719474155102
ko05205	Proteoglycans in cancer	14/685	271/7206	0.0109334244823
ko04120	Ubiquitin mediated proteolysis	5/685	138/7206	0.0123865390285
ko00230	Purine metabolism	29/685	194/7206	0.0126362637121
ko04540	Gap junction	21/685	128/7206	0.0136565495438
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/685	182/7206	0.0144153465018
ko04930	Type II diabetes mellitus	11/685	54/7206	0.0158008602104
ko00512	Mucin type O-glycan biosynthesis	7/685	29/7206	0.0165469376913
ko04062	Chemokine signaling pathway	29/685	201/7206	0.0201742404919
ko04140	Autophagy - animal	7/685	164/7206	0.0208574572664
ko04137	Mitophagy - animal	2/685	82/7206	0.0220356746302
ko04924	Renin secretion	15/685	86/7206	0.0237387711966
ko04918	Thyroid hormone synthesis	15/685	86/7206	0.0237387711966
ko05231	Choline metabolism in cancer	21/685	134/7206	0.0240688807855
ko04510	Focal adhesion	13/685	240/7206	0.0249723363297
ko04330	Notch signaling pathway	1/685	62/7206	0.0276360719828
ko04640	Hematopoietic cell lineage	1/685	64/7206	0.0287196990807
ko04071	Sphingolipid signaling pathway	24/685	162/7206	0.0288169234155
ko04810	Regulation of actin cytoskeleton	15/685	264/7206	0.0317769918916
ko04966	Collecting duct acid secretion	6/685	26/7206	0.0318579121897
ko04064	NF-kappa B signaling pathway	3/685	96/7206	0.0331389512644
ko04670	Leukocyte transendothelial migration	7/685	151/7206	0.0353022547201
ko05410	Hypertrophic cardiomyopathy (HCM)	16/685	100/7206	0.037021997291
ko05010	Alzheimer's disease	28/685	202/7206	0.0381157640948
ko04550	Signaling pathways regulating pluripotency of stem cells	8/685	165/7206	0.0425602382751
ko05140	Leishmaniasis	2/685	75/7206	0.0448226478091
ko04923	Regulation of lipolysis in adipocytes	13/685	77/7206	0.0468251774814
ko05161	Hepatitis B	9/685	173/7206	0.0489497862439