ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	161/953	423/7206	1.01580014448e-40
ko04724	Glutamatergic synapse	82/953	152/7206	1.06891344771e-33
ko05033	Nicotine addiction	46/953	56/7206	1.39305699451e-31
ko05032	Morphine addiction	62/953	110/7206	4.29058011854e-27
ko04727	GABAergic synapse	60/953	110/7206	3.23175711434e-25
ko04728	Dopaminergic synapse	77/953	185/7206	2.40274837613e-22
ko04713	Circadian entrainment	64/953	136/7206	3.31491634568e-22
ko04725	Cholinergic synapse	69/953	160/7206	3.62616349113e-21
ko04723	Retrograde endocannabinoid signaling	72/953	175/7206	1.33052518536e-20
ko04024	cAMP signaling pathway	93/953	279/7206	8.86940726535e-19
ko04721	Synaptic vesicle cycle	42/953	80/7206	3.54862674632e-17
ko04911	Insulin secretion	49/953	117/7206	9.5949274281e-15
ko04261	Adrenergic signaling in cardiomyocytes	68/953	205/7206	7.20090701975e-14
ko04742	Taste transduction	32/953	61/7206	2.2421387105e-13
ko04921	Oxytocin signaling pathway	66/953	209/7206	2.34191513419e-12
ko04726	Serotonergic synapse	49/953	137/7206	1.13653018057e-11
ko04020	Calcium signaling pathway	76/953	265/7206	1.37016083854e-11
ko04720	Long-term potentiation	36/953	99/7206	3.82379117883e-09
ko05031	Amphetamine addiction	34/953	91/7206	4.62565371833e-09
ko04744	Phototransduction	19/953	36/7206	1.5921844091e-08
ko03040	Spliceosome	1/953	145/7206	3.63161936222e-08
ko05030	Cocaine addiction	28/953	73/7206	5.53888016632e-08
ko04360	Axon guidance	60/953	233/7206	1.85931188513e-07
ko04010	MAPK signaling pathway	76/953	321/7206	1.87198586419e-07
ko04970	Salivary secretion	32/953	95/7206	2.22873202459e-07
ko05203	Viral carcinogenesis	12/953	277/7206	7.59506700921e-07
ko04925	Aldosterone synthesis and secretion	33/953	105/7206	1.1909318426e-06
ko04972	Pancreatic secretion	34/953	111/7206	1.31145021229e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	27/953	79/7206	1.42117989715e-06
ko04060	Cytokine-cytokine receptor interaction	6/953	191/7206	2.23531821435e-06
ko04971	Gastric acid secretion	31/953	98/7206	2.45544970768e-06
ko04072	Phospholipase D signaling pathway	50/953	197/7206	3.08865927771e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/953	74/7206	4.41432792637e-06
ko03013	RNA transport	5/953	166/7206	7.86561259333e-06
ko04514	Cell adhesion molecules (CAMs)	36/953	130/7206	9.71561584675e-06
ko04022	cGMP-PKG signaling pathway	52/953	216/7206	1.37107396345e-05
ko05414	Dilated cardiomyopathy	32/953	112/7206	1.44426143554e-05
ko05168	Herpes simplex infection	7/953	182/7206	3.11469508898e-05
ko05322	Systemic lupus erythematosus	5/953	151/7206	4.77950458446e-05
ko04260	Cardiac muscle contraction	28/953	98/7206	5.63174491375e-05
ko05164	Influenza A	7/953	167/7206	0.000119066397747
ko04961	Endocrine and other factor-regulated calcium reabsorption	19/953	59/7206	0.000128348325117
ko04730	Long-term depression	23/953	78/7206	0.000135035786713
ko04740	Olfactory transduction	23/953	80/7206	0.000194455245247
ko04120	Ubiquitin mediated proteolysis	5/953	138/7206	0.000196392649205
ko04915	Estrogen signaling pathway	33/953	131/7206	0.00020454559707
ko05205	Proteoglycans in cancer	17/953	271/7206	0.000237938419969
ko03008	Ribosome biogenesis in eukaryotes	1/953	79/7206	0.000316811710924
ko04014	Ras signaling pathway	57/953	279/7206	0.000579863827914
ko04070	Phosphatidylinositol signaling system	28/953	112/7206	0.000627165263626
ko04371	Apelin signaling pathway	40/953	177/7206	0.000649465717899
ko04141	Protein processing in endoplasmic reticulum	10/953	184/7206	0.000837558622755
ko00240	Pyrimidine metabolism	4/953	110/7206	0.00100567361745
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/953	14/7206	0.00101875850331
ko04966	Collecting duct acid secretion	10/953	26/7206	0.0011162210639
ko04621	NOD-like receptor signaling pathway	8/953	157/7206	0.00117510951047
ko05410	Hypertrophic cardiomyopathy (HCM)	25/953	100/7206	0.0014632564824
ko04640	Hematopoietic cell lineage	1/953	64/7206	0.0023765340743
ko04745	Phototransduction - fly	12/953	38/7206	0.0026668226072
ko05140	Leishmaniasis	2/953	75/7206	0.0031201177837
ko04612	Antigen processing and presentation	2/953	77/7206	0.00330424616755
ko00515	Mannose type O-glycan biosynthesis	9/953	25/7206	0.00335109711797
ko04540	Gap junction	29/953	128/7206	0.00336062105125
ko05321	Inflammatory bowel disease (IBD)	1/953	56/7206	0.00513249389023
ko03018	RNA degradation	3/953	84/7206	0.00525090567816
ko04924	Renin secretion	21/953	86/7206	0.00558473098783
ko04064	NF-kappa B signaling pathway	4/953	96/7206	0.00567693834649
ko04923	Regulation of lipolysis in adipocytes	19/953	77/7206	0.00594946787165
ko00520	Amino sugar and nucleotide sugar metabolism	1/953	55/7206	0.00786181020623
ko00480	Glutathione metabolism	1/953	55/7206	0.00786181020623
ko05110	Vibrio cholerae infection	16/953	63/7206	0.00794757216752
ko04015	Rap1 signaling pathway	52/953	278/7206	0.00857216868656
ko04110	Cell cycle	9/953	145/7206	0.00896233326614
ko04964	Proximal tubule bicarbonate reclamation	9/953	29/7206	0.0100779651841
ko04146	Peroxisome	4/953	89/7206	0.0109492120759
ko04976	Bile secretion	19/953	80/7206	0.0113637372325
ko00590	Arachidonic acid metabolism	1/953	52/7206	0.0116831186683
ko05161	Hepatitis B	12/953	173/7206	0.0119505441851
ko04930	Type II diabetes mellitus	14/953	54/7206	0.0131092093388
ko05162	Measles	7/953	120/7206	0.0137128562055
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/953	182/7206	0.0141363010298
ko04750	Inflammatory mediator regulation of TRP channels	26/953	122/7206	0.0142617914774
ko00310	Lysine degradation	3/953	73/7206	0.0147998371026
ko05169	Epstein-Barr virus infection	16/953	206/7206	0.0162460649279
ko01200	Carbon metabolism	8/953	128/7206	0.0170384741901
ko00330	Arginine and proline metabolism	2/953	61/7206	0.0204225302175
ko04912	GnRH signaling pathway	25/953	122/7206	0.0215792542784
ko03022	Basal transcription factors	1/953	44/7206	0.0246023291668
ko00071	Fatty acid degradation	1/953	45/7206	0.0248913859359
ko00620	Pyruvate metabolism	1/953	46/7206	0.0256736112328
ko03420	Nucleotide excision repair	1/953	46/7206	0.0256736112328
ko03320	PPAR signaling pathway	3/953	69/7206	0.0298894851382
ko05034	Alcoholism	43/953	238/7206	0.0317039460398
ko04217	Necroptosis	14/953	178/7206	0.0326864021808
ko04071	Sphingolipid signaling pathway	31/953	162/7206	0.0337250332705
ko00983	Drug metabolism - other enzymes	1/953	42/7206	0.0367582903087
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/953	15/7206	0.0384302048062
ko00280	Valine, leucine and isoleucine degradation	2/953	54/7206	0.0408676866421
ko04722	Neurotrophin signaling pathway	30/953	160/7206	0.0441345139702