ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	156/988	423/7206	1.9638757494e-35
ko05033	Nicotine addiction	46/988	56/7206	7.21076765461e-31
ko04724	Glutamatergic synapse	78/988	152/7206	5.14697103972e-29
ko04727	GABAergic synapse	60/988	110/7206	2.28723875784e-24
ko05032	Morphine addiction	59/988	110/7206	1.79613706409e-23
ko04728	Dopaminergic synapse	76/988	185/7206	1.13179766108e-20
ko04713	Circadian entrainment	63/988	136/7206	1.41954445869e-20
ko04723	Retrograde endocannabinoid signaling	71/988	175/7206	5.1791360252e-19
ko04721	Synaptic vesicle cycle	44/988	80/7206	2.32241835956e-18
ko04744	Phototransduction	28/988	36/7206	4.93659903034e-18
ko04725	Cholinergic synapse	65/988	160/7206	1.57514586315e-17
ko04742	Taste transduction	35/988	61/7206	1.23502139876e-15
ko04024	cAMP signaling pathway	85/988	279/7206	1.18953471307e-13
ko04726	Serotonergic synapse	52/988	137/7206	7.39615340054e-13
ko04020	Calcium signaling pathway	79/988	265/7206	3.79919795856e-12
ko04740	Olfactory transduction	36/988	80/7206	8.08099195823e-12
ko04911	Insulin secretion	45/988	117/7206	1.57961365311e-11
ko05031	Amphetamine addiction	38/988	91/7206	3.42495279676e-11
ko04921	Oxytocin signaling pathway	65/988	209/7206	5.23782932424e-11
ko04720	Long-term potentiation	36/988	99/7206	1.020344388e-08
ko03040	Spliceosome	1/988	145/7206	1.46610552466e-08
ko04261	Adrenergic signaling in cardiomyocytes	58/988	205/7206	2.4679084061e-08
ko05164	Influenza A	3/988	167/7206	8.34348405783e-08
ko04970	Salivary secretion	33/988	95/7206	1.49450619915e-07
ko05203	Viral carcinogenesis	12/988	277/7206	2.62575397693e-07
ko04745	Phototransduction - fly	18/988	38/7206	5.6287658715e-07
ko04925	Aldosterone synthesis and secretion	34/988	105/7206	8.19722974228e-07
ko05322	Systemic lupus erythematosus	3/988	151/7206	9.14043016316e-07
ko04060	Cytokine-cytokine receptor interaction	6/988	191/7206	1.02507919431e-06
ko04971	Gastric acid secretion	32/988	98/7206	1.60445218722e-06
ko05030	Cocaine addiction	26/988	73/7206	1.81555848694e-06
ko05162	Measles	2/988	120/7206	6.05801041201e-06
ko05168	Herpes simplex infection	7/988	182/7206	1.50340828088e-05
ko04621	NOD-like receptor signaling pathway	5/988	157/7206	1.64026890137e-05
ko04966	Collecting duct acid secretion	12/988	26/7206	6.24372313465e-05
ko03013	RNA transport	7/988	166/7206	8.25610828633e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/988	74/7206	0.000103145318219
ko05166	HTLV-I infection	19/988	292/7206	0.000116697943701
ko05161	Hepatitis B	8/988	173/7206	0.000120718924953
ko05169	Epstein-Barr virus infection	11/988	206/7206	0.00012519190517
ko04514	Cell adhesion molecules (CAMs)	34/988	130/7206	0.000144387875365
ko04010	MAPK signaling pathway	68/988	321/7206	0.000170275996222
ko04110	Cell cycle	6/988	145/7206	0.000210135597522
ko04972	Pancreatic secretion	30/988	111/7206	0.000217790314421
ko04070	Phosphatidylinositol signaling system	30/988	112/7206	0.000236097876979
ko04120	Ubiquitin mediated proteolysis	6/988	138/7206	0.000412786372634
ko04022	cGMP-PKG signaling pathway	48/988	216/7206	0.000569261701814
ko05205	Proteoglycans in cancer	19/988	271/7206	0.000583159300747
ko04730	Long-term depression	22/988	78/7206	0.00069302291154
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/988	79/7206	0.000795469534631
ko04064	NF-kappa B signaling pathway	3/988	96/7206	0.000844740650757
ko04260	Cardiac muscle contraction	26/988	98/7206	0.000899641615173
ko04964	Proximal tubule bicarbonate reclamation	11/988	29/7206	0.000990506413742
ko03008	Ribosome biogenesis in eukaryotes	2/988	79/7206	0.00144437408269
ko04072	Phospholipase D signaling pathway	43/988	197/7206	0.00151805002859
ko05140	Leishmaniasis	2/988	75/7206	0.00208419902678
ko04612	Antigen processing and presentation	2/988	77/7206	0.00218216691085
ko05016	Huntington's disease	15/988	215/7206	0.00239125826353
ko05200	Pathways in cancer	46/988	492/7206	0.0027730833662
ko04510	Focal adhesion	18/988	240/7206	0.00300083078463
ko04141	Protein processing in endoplasmic reticulum	12/988	184/7206	0.00312020059344
ko04924	Renin secretion	22/988	86/7206	0.00383131975342
ko05110	Vibrio cholerae infection	17/988	63/7206	0.00484052385606
ko04750	Inflammatory mediator regulation of TRP channels	28/988	122/7206	0.0049290474168
ko00280	Valine, leucine and isoleucine degradation	1/988	54/7206	0.00502138408756
ko00480	Glutathione metabolism	1/988	55/7206	0.00503304398187
ko04550	Signaling pathways regulating pluripotency of stem cells	11/988	165/7206	0.00572871197123
ko04630	Jak-STAT signaling pathway	8/988	132/7206	0.0070292253179
ko04626	Plant-pathogen interaction	7/988	18/7206	0.00715691526523
ko05130	Pathogenic Escherichia coli infection	3/988	77/7206	0.0072495306349
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/988	14/7206	0.00735796310724
ko04610	Complement and coagulation cascades	3/988	79/7206	0.0074863127251
ko05215	Prostate cancer	6/988	111/7206	0.00768862438867
ko04930	Type II diabetes mellitus	15/988	54/7206	0.00806710171089
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/988	182/7206	0.00834650229544
ko04657	IL-17 signaling pathway	4/988	87/7206	0.0109925839717
ko00562	Inositol phosphate metabolism	21/988	89/7206	0.0119005700023
ko05145	Toxoplasmosis	8/988	126/7206	0.0125579584471
ko04976	Bile secretion	19/988	80/7206	0.0133996196758
ko04140	Autophagy - animal	12/988	164/7206	0.0152596211321
ko04210	Apoptosis	14/988	180/7206	0.0157364030498
ko05144	Malaria	1/988	45/7206	0.016409954831
ko03420	Nucleotide excision repair	1/988	46/7206	0.0164487911606
ko05217	Basal cell carcinoma	3/988	68/7206	0.0204700847779
ko04668	TNF signaling pathway	8/988	120/7206	0.0221159152114
ko03022	Basal transcription factors	1/988	44/7206	0.0249201199254
ko04360	Axon guidance	44/988	233/7206	0.0254262530878
ko05414	Dilated cardiomyopathy	24/988	112/7206	0.0254295562615
ko05224	Breast cancer	14/988	174/7206	0.0254536092603
ko04014	Ras signaling pathway	51/988	279/7206	0.0264867986574
ko05416	Viral myocarditis	2/988	55/7206	0.0281214767252
ko04146	Peroxisome	5/988	89/7206	0.0281713083584
ko01524	Platinum drug resistance	4/988	76/7206	0.028401353504
ko05321	Inflammatory bowel disease (IBD)	2/988	56/7206	0.0290120515885
ko05418	Fluid shear stress and atherosclerosis	14/988	173/7206	0.0326313733848
ko05020	Prion diseases	1/988	40/7206	0.0359052375027
ko04540	Gap junction	26/988	128/7206	0.0369586060585
ko03018	RNA degradation	5/988	84/7206	0.0369828225026
ko05220	Chronic myeloid leukemia	5/988	85/7206	0.0374373381665
ko04214	Apoptosis - fly	4/988	72/7206	0.0389680866517
ko04115	p53 signaling pathway	4/988	74/7206	0.0395139235143
ko04330	Notch signaling pathway	3/988	62/7206	0.0401686932744
ko04622	RIG-I-like receptor signaling pathway	3/988	62/7206	0.0401686932744
ko00590	Arachidonic acid metabolism	2/988	52/7206	0.0402457974169
ko05202	Transcriptional misregulation in cancer	16/988	188/7206	0.040325051989
ko04710	Circadian rhythm	11/988	43/7206	0.0406828787578
ko04810	Regulation of actin cytoskeleton	25/988	264/7206	0.0443736087693
ko05206	MicroRNAs in cancer	15/988	177/7206	0.0454682059327
ko00240	Pyrimidine metabolism	8/988	110/7206	0.0496912347639