ko pathway ratio_in_study ratio_in_pop p_value ko04974 Protein digestion and absorption 25/432 96/7206 2.00019011042e-10 ko00380 Tryptophan metabolism 17/432 50/7206 1.91758157401e-09 ko04610 Complement and coagulation cascades 20/432 79/7206 2.28345254877e-08 ko00590 Arachidonic acid metabolism 16/432 52/7206 2.95902089862e-08 ko00120 Primary bile acid biosynthesis 10/432 20/7206 5.80881969348e-08 ko00360 Phenylalanine metabolism 9/432 17/7206 1.45583533173e-07 ko04976 Bile secretion 19/432 80/7206 1.55666696882e-07 ko00591 Linoleic acid metabolism 10/432 22/7206 1.82286765633e-07 ko00350 Tyrosine metabolism 12/432 33/7206 2.0723219057e-07 ko04614 Renin-angiotensin system 9/432 18/7206 2.75821435983e-07 ko00592 alpha-Linolenic acid metabolism 9/432 19/7206 4.96454010056e-07 ko00071 Fatty acid degradation 13/432 45/7206 1.34782520305e-06 ko00140 Steroid hormone biosynthesis 12/432 41/7206 2.96971043064e-06 ko00983 Drug metabolism - other enzymes 12/432 42/7206 3.93515989487e-06 ko00830 Retinol metabolism 12/432 42/7206 3.93515989487e-06 ko04146 Peroxisome 18/432 89/7206 4.05832261295e-06 ko03320 PPAR signaling pathway 15/432 69/7206 1.03133193962e-05 ko00982 Drug metabolism - cytochrome P450 10/432 37/7206 4.34355071786e-05 ko00040 Pentose and glucuronate interconversions 8/432 26/7206 9.35919721916e-05 ko05204 Chemical carcinogenesis 11/432 48/7206 9.47265862636e-05 ko00950 Isoquinoline alkaloid biosynthesis 5/432 10/7206 0.000148296537244 ko04975 Fat digestion and absorption 9/432 35/7206 0.000160255893167 ko04144 Endocytosis 6/432 342/7206 0.000163406608792 ko00362 Benzoate degradation 4/432 6/7206 0.000173498856943 ko00053 Ascorbate and aldarate metabolism 7/432 22/7206 0.000205510337621 ko02010 ABC transporters 9/432 39/7206 0.000388219370319 ko00260 Glycine, serine and threonine metabolism 10/432 48/7206 0.00045007955878 ko03013 RNA transport 1/432 166/7206 0.000712735705801 ko01212 Fatty acid metabolism 11/432 60/7206 0.000748829335588 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 3/432 4/7206 0.000817977651779 ko00643 Styrene degradation 3/432 4/7206 0.000817977651779 ko04972 Pancreatic secretion 16/432 111/7206 0.000879250721315 ko04390 Hippo signaling pathway 2/432 188/7206 0.00148983505499 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 3/432 5/7206 0.00195387349946 ko04310 Wnt signaling pathway 2/432 181/7206 0.00212744259416 ko00980 Metabolism of xenobiotics by cytochrome P450 8/432 40/7206 0.00219683878305 ko03040 Spliceosome 1/432 145/7206 0.0022127603077 ko04110 Cell cycle 1/432 145/7206 0.0022127603077 ko00340 Histidine metabolism 6/432 25/7206 0.0029885805776 ko00330 Arginine and proline metabolism 10/432 61/7206 0.00308755808536 ko00640 Propanoate metabolism 7/432 34/7206 0.00346886234552 ko00561 Glycerolipid metabolism 10/432 63/7206 0.00393223971971 ko00410 beta-Alanine metabolism 7/432 35/7206 0.00411731095868 ko00500 Starch and sucrose metabolism 7/432 35/7206 0.00411731095868 ko04550 Signaling pathways regulating pluripotency of stem cells 2/432 165/7206 0.00423812967068 ko05150 Staphylococcus aureus infection 7/432 36/7206 0.00485353878282 ko00620 Pyruvate metabolism 8/432 46/7206 0.00544062638355 ko05200 Pathways in cancer 16/432 492/7206 0.00572830289534 ko04360 Axon guidance 5/432 233/7206 0.00737335772386 ko05034 Alcoholism 5/432 238/7206 0.00757629384259 ko04977 Vitamin digestion and absorption 5/432 22/7206 0.00851689878777 ko04724 Glutamatergic synapse 2/432 152/7206 0.00861536649225 ko04978 Mineral absorption 7/432 40/7206 0.00881912620161 ko04723 Retrograde endocannabinoid signaling 3/432 175/7206 0.00952772465512 ko05224 Breast cancer 3/432 174/7206 0.0137963469228 ko00860 Porphyrin and chlorophyll metabolism 6/432 34/7206 0.014385936181 ko04270 Vascular smooth muscle contraction 17/432 154/7206 0.0145315325129 ko01040 Biosynthesis of unsaturated fatty acids 5/432 25/7206 0.0148224244088 ko04114 Oocyte meiosis 2/432 139/7206 0.0173530652894 ko05016 Huntington's disease 5/432 215/7206 0.0185002156688 ko00920 Sulfur metabolism 3/432 10/7206 0.0187107882343 ko04520 Adherens junction 1/432 103/7206 0.020811849678 ko00630 Glyoxylate and dicarboxylate metabolism 6/432 38/7206 0.0241579187189 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 3/432 11/7206 0.024603121026 ko04080 Neuroactive ligand-receptor interaction 15/432 423/7206 0.0263365554271 ko05203 Viral carcinogenesis 8/432 277/7206 0.026995872433 ko05211 Renal cell carcinoma 1/432 96/7206 0.0300790434718 ko05100 Bacterial invasion of epithelial cells 1/432 99/7206 0.0304094615794 ko00281 Geraniol degradation 2/432 5/7206 0.0317689381526 ko00100 Steroid biosynthesis 4/432 21/7206 0.033810402918 ko04666 Fc gamma R-mediated phagocytosis 2/432 122/7206 0.0338865450241 ko05322 Systemic lupus erythematosus 3/432 151/7206 0.035443192523 ko00565 Ether lipid metabolism 6/432 42/7206 0.0375985347878 ko04630 Jak-STAT signaling pathway 14/432 132/7206 0.0383844781464 ko05134 Legionellosis 9/432 74/7206 0.0419372230307 ko04611 Platelet activation 16/432 163/7206 0.0445369357395 ko04612 Antigen processing and presentation 9/432 77/7206 0.0481483069052