ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	159/976	423/7206	5.07691511537e-38
ko04724	Glutamatergic synapse	78/976	152/7206	2.19655095691e-29
ko05033	Nicotine addiction	43/976	56/7206	6.60221541387e-27
ko04721	Synaptic vesicle cycle	48/976	80/7206	2.15266338166e-22
ko05032	Morphine addiction	57/976	110/7206	5.34539965454e-22
ko04713	Circadian entrainment	64/976	136/7206	1.23735967514e-21
ko04728	Dopaminergic synapse	75/976	185/7206	2.50451991452e-20
ko04727	GABAergic synapse	53/976	110/7206	1.10577210562e-18
ko04725	Cholinergic synapse	65/976	160/7206	8.29831544819e-18
ko04723	Retrograde endocannabinoid signaling	68/976	175/7206	2.32424004416e-17
ko04911	Insulin secretion	50/976	117/7206	5.04986933331e-15
ko04024	cAMP signaling pathway	87/976	279/7206	6.78149207087e-15
ko04020	Calcium signaling pathway	83/976	265/7206	2.70427359079e-14
ko04921	Oxytocin signaling pathway	69/976	209/7206	2.39542821917e-13
ko04726	Serotonergic synapse	52/976	137/7206	4.52112412472e-13
ko04742	Taste transduction	30/976	61/7206	2.05932142931e-11
ko05031	Amphetamine addiction	37/976	91/7206	1.10332349746e-10
ko04720	Long-term potentiation	38/976	99/7206	4.59358950587e-10
ko04261	Adrenergic signaling in cardiomyocytes	60/976	205/7206	2.33028852901e-09
ko04744	Phototransduction	20/976	36/7206	3.05847373768e-09
ko04970	Salivary secretion	35/976	95/7206	7.9902186542e-09
ko04925	Aldosterone synthesis and secretion	35/976	105/7206	1.48628308729e-07
ko03010	Ribosome	1/976	129/7206	1.85506039346e-07
ko03040	Spliceosome	2/976	145/7206	2.48032915979e-07
ko04971	Gastric acid secretion	33/976	98/7206	2.57426696561e-07
ko05030	Cocaine addiction	26/976	73/7206	1.43395499005e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	26/976	74/7206	1.93069107523e-06
ko05168	Herpes simplex infection	6/976	182/7206	4.57084453684e-06
ko04730	Long-term depression	26/976	78/7206	5.91988210933e-06
ko05322	Systemic lupus erythematosus	4/976	151/7206	5.96197090143e-06
ko04120	Ubiquitin mediated proteolysis	3/976	138/7206	6.59026387832e-06
ko04966	Collecting duct acid secretion	13/976	26/7206	8.98146044319e-06
ko04740	Olfactory transduction	26/976	80/7206	9.97432765126e-06
ko04745	Phototransduction - fly	16/976	38/7206	1.35452906671e-05
ko05203	Viral carcinogenesis	15/976	277/7206	1.39365548138e-05
ko04010	MAPK signaling pathway	71/976	321/7206	1.76031465745e-05
ko04514	Cell adhesion molecules (CAMs)	36/976	130/7206	2.21088110615e-05
ko04360	Axon guidance	55/976	233/7206	2.31224249119e-05
ko03013	RNA transport	6/976	166/7206	2.67916962294e-05
ko04022	cGMP-PKG signaling pathway	51/976	216/7206	4.48880378044e-05
ko05110	Vibrio cholerae infection	21/976	63/7206	4.61489985513e-05
ko04540	Gap junction	34/976	128/7206	7.06076416341e-05
ko04750	Inflammatory mediator regulation of TRP channels	33/976	122/7206	7.48460707873e-05
ko04621	NOD-like receptor signaling pathway	6/976	157/7206	7.69898187057e-05
ko04060	Cytokine-cytokine receptor interaction	9/976	191/7206	9.2983124212e-05
ko04972	Pancreatic secretion	30/976	111/7206	0.000128244446006
ko04915	Estrogen signaling pathway	33/976	131/7206	0.000269318704238
ko05164	Influenza A	8/976	167/7206	0.000329604905174
ko04070	Phosphatidylinositol signaling system	29/976	112/7206	0.00040745033427
ko04014	Ras signaling pathway	58/976	279/7206	0.000647186630929
ko04072	Phospholipase D signaling pathway	44/976	197/7206	0.000648544550245
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/976	79/7206	0.00070561526972
ko04110	Cell cycle	7/976	145/7206	0.000837480506558
ko04064	NF-kappa B signaling pathway	3/976	96/7206	0.000853049003394
ko04626	Plant-pathogen interaction	8/976	18/7206	0.00136724098997
ko04141	Protein processing in endoplasmic reticulum	11/976	184/7206	0.00141459204935
ko03008	Ribosome biogenesis in eukaryotes	2/976	79/7206	0.00144086077923
ko04260	Cardiac muscle contraction	25/976	98/7206	0.00147366233318
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/976	59/7206	0.00175260917363
ko04612	Antigen processing and presentation	2/976	77/7206	0.00213287120004
ko04922	Glucagon signaling pathway	30/976	128/7206	0.0023881343361
ko04146	Peroxisome	3/976	89/7206	0.00258657231055
ko05140	Leishmaniasis	2/976	75/7206	0.00322113764229
ko04964	Proximal tubule bicarbonate reclamation	10/976	29/7206	0.00346746807194
ko04371	Apelin signaling pathway	38/976	177/7206	0.00354534257975
ko05162	Measles	6/976	120/7206	0.00423974699073
ko04976	Bile secretion	20/976	80/7206	0.00486832886156
ko05414	Dilated cardiomyopathy	26/976	112/7206	0.00490273168055
ko04710	Circadian rhythm	13/976	43/7206	0.00531231614312
ko04924	Renin secretion	21/976	86/7206	0.00621560152243
ko05169	Epstein-Barr virus infection	15/976	206/7206	0.00687467270189
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/976	14/7206	0.00692343030529
ko04610	Complement and coagulation cascades	3/976	79/7206	0.00736489479107
ko00590	Arachidonic acid metabolism	1/976	52/7206	0.00750265090148
ko00280	Valine, leucine and isoleucine degradation	1/976	54/7206	0.00784925897786
ko04114	Oocyte meiosis	30/976	139/7206	0.00814601533506
ko04960	Aldosterone-regulated sodium reabsorption	12/976	41/7206	0.00899852716104
ko05161	Hepatitis B	12/976	173/7206	0.00919522880338
ko05205	Proteoglycans in cancer	23/976	271/7206	0.011155475407
ko05120	Epithelial cell signaling in Helicobacter pylori infection	21/976	92/7206	0.0134165054406
ko00330	Arginine and proline metabolism	2/976	61/7206	0.0135120506014
ko04330	Notch signaling pathway	2/976	62/7206	0.0137664604516
ko04214	Apoptosis - fly	3/976	72/7206	0.0146253774756
ko04912	GnRH signaling pathway	26/976	122/7206	0.0158145309592
ko03420	Nucleotide excision repair	1/976	46/7206	0.0164787978301
ko05410	Hypertrophic cardiomyopathy (HCM)	22/976	100/7206	0.0178945093171
ko05166	HTLV-I infection	26/976	292/7206	0.0180417056297
ko00562	Inositol phosphate metabolism	20/976	89/7206	0.018649919282
ko04630	Jak-STAT signaling pathway	9/976	132/7206	0.0203072379607
ko04973	Carbohydrate digestion and absorption	11/976	42/7206	0.0232307635889
ko00240	Pyrimidine metabolism	7/976	110/7206	0.0240329466796
ko03022	Basal transcription factors	1/976	44/7206	0.0246703398587
ko04916	Melanogenesis	29/976	142/7206	0.0247343717927
ko05144	Malaria	1/976	45/7206	0.0255009658919
ko00071	Fatty acid degradation	1/976	45/7206	0.0255009658919
ko00480	Glutathione metabolism	2/976	55/7206	0.0279258164086
ko04962	Vasopressin-regulated water reabsorption	14/976	58/7206	0.0310096703751
ko04015	Rap1 signaling pathway	50/976	278/7206	0.0316865845414
ko00980	Metabolism of xenobiotics by cytochrome P450	1/976	40/7206	0.0359245249686
ko04115	p53 signaling pathway	4/976	74/7206	0.0392328681198
ko00680	Methane metabolism	9/976	34/7206	0.0400786403347
ko04622	RIG-I-like receptor signaling pathway	3/976	62/7206	0.0402804623824
ko04640	Hematopoietic cell lineage	3/976	64/7206	0.0410822028831
ko04510	Focal adhesion	22/976	240/7206	0.043745776297
ko05206	MicroRNAs in cancer	15/976	177/7206	0.0451728254395
ko05214	Glioma	17/976	79/7206	0.0460405342088