ko pathway ratio_in_study ratio_in_pop p_value ko04512 ECM-receptor interaction 13/145 79/7206 4.3659723133e-09 ko04510 Focal adhesion 20/145 240/7206 5.50879530473e-08 ko04668 TNF signaling pathway 13/145 120/7206 7.14802782103e-07 ko05205 Proteoglycans in cancer 18/145 271/7206 7.2619923607e-06 ko04933 AGE-RAGE signaling pathway in diabetic complications 12/145 135/7206 1.54785893495e-05 ko05146 Amoebiasis 10/145 99/7206 2.6926313509e-05 ko04060 Cytokine-cytokine receptor interaction 14/145 191/7206 2.72063657779e-05 ko04621 NOD-like receptor signaling pathway 12/145 157/7206 6.97221248731e-05 ko04912 GnRH signaling pathway 10/145 122/7206 0.000160630406251 ko01522 Endocrine resistance 10/145 124/7206 0.000183782650526 ko04670 Leukocyte transendothelial migration 11/145 151/7206 0.000215913297852 ko05131 Shigellosis 8/145 82/7206 0.000224649648658 ko05120 Epithelial cell signaling in Helicobacter pylori infection 8/145 92/7206 0.000495465361945 ko05164 Influenza A 11/145 167/7206 0.000515246992472 ko04974 Protein digestion and absorption 8/145 96/7206 0.000659740979446 ko05410 Hypertrophic cardiomyopathy (HCM) 8/145 100/7206 0.000865441977598 ko05145 Toxoplasmosis 9/145 126/7206 0.000941640134612 ko04210 Apoptosis 11/145 180/7206 0.000964023834022 ko05160 Hepatitis C 10/145 153/7206 0.00098410097335 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 7/145 79/7206 0.000999173000917 ko04151 PI3K-Akt signaling pathway 18/145 390/7206 0.00107078406403 ko04611 Platelet activation 10/145 163/7206 0.0015924315429 ko04657 IL-17 signaling pathway 7/145 87/7206 0.00176260060189 ko05133 Pertussis 7/145 87/7206 0.00176260060189 ko04144 Endocytosis 16/145 342/7206 0.00215202946859 ko05161 Hepatitis B 10/145 173/7206 0.00247639224257 ko05219 Bladder cancer 5/145 48/7206 0.00262838760288 ko04658 Th1 and Th2 cell differentiation 7/145 96/7206 0.00309521552896 ko05134 Legionellosis 6/145 74/7206 0.00360366953099 ko05100 Bacterial invasion of epithelial cells 7/145 99/7206 0.00367791733117 ko05142 Chagas disease (American trypanosomiasis) 8/145 130/7206 0.00456056682825 ko04380 Osteoclast differentiation 8/145 134/7206 0.00547130101579 ko05414 Dilated cardiomyopathy 7/145 112/7206 0.00721463222312 ko05418 Fluid shear stress and atherosclerosis 9/145 173/7206 0.00798999414817 ko04623 Cytosolic DNA-sensing pathway 4/145 41/7206 0.00894162667036 ko04932 Non-alcoholic fatty liver disease (NAFLD) 9/145 182/7206 0.0109528325886 ko05144 Malaria 4/145 45/7206 0.0123685995231 ko04064 NF-kappa B signaling pathway 6/145 96/7206 0.0125964865052 ko05152 Tuberculosis 9/145 187/7206 0.0129206050063 ko05132 Salmonella infection 6/145 98/7206 0.0138456258089 ko04215 Apoptosis - multiple species 4/145 47/7206 0.0143579421597 ko05167 Kaposi's sarcoma-associated herpesvirus infection 9/145 191/7206 0.0146758052469 ko04620 Toll-like receptor signaling pathway 6/145 100/7206 0.0151789685738 ko04071 Sphingolipid signaling pathway 8/145 162/7206 0.0162352501262 ko04915 Estrogen signaling pathway 7/145 131/7206 0.0162409214325 ko05014 Amyotrophic lateral sclerosis (ALS) 5/145 74/7206 0.0163272387892 ko00512 Mucin type O-glycan biosynthesis 3/145 29/7206 0.0198922575484 ko05212 Pancreatic cancer 5/145 83/7206 0.025521293046 ko05206 MicroRNAs in cancer 8/145 177/7206 0.026085423452 ko04218 Cellular senescence 8/145 177/7206 0.026085423452 ko04217 Necroptosis 8/145 178/7206 0.0268636361001 ko05200 Pathways in cancer 17/145 492/7206 0.0283969797946 ko05210 Colorectal cancer 5/145 86/7206 0.0291972465883 ko04662 B cell receptor signaling pathway 5/145 88/7206 0.0318248753217 ko05222 Small cell lung cancer 5/145 89/7206 0.0331925344772 ko04622 RIG-I-like receptor signaling pathway 4/145 62/7206 0.035698026458 ko04672 Intestinal immune network for IgA production 3/145 37/7206 0.0376735743481 ko04010 MAPK signaling pathway 12/145 321/7206 0.0378932725565 ko04660 T cell receptor signaling pathway 6/145 124/7206 0.0385967145418 ko04722 Neurotrophin signaling pathway 7/145 160/7206 0.0421857819565 ko04080 Neuroactive ligand-receptor interaction 3/145 423/7206 0.048115349854