ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	145/912	423/7206	7.25011416576e-33
ko04724	Glutamatergic synapse	75/912	152/7206	8.06962612975e-29
ko05033	Nicotine addiction	43/912	56/7206	3.80411321948e-28
ko04713	Circadian entrainment	60/912	136/7206	4.14667195206e-20
ko04728	Dopaminergic synapse	69/912	185/7206	4.25333688005e-18
ko04723	Retrograde endocannabinoid signaling	66/912	175/7206	1.20202887878e-17
ko05032	Morphine addiction	50/912	110/7206	1.2870290725e-17
ko04727	GABAergic synapse	48/912	110/7206	4.41075734208e-16
ko04020	Calcium signaling pathway	83/912	265/7206	4.65642901703e-16
ko04921	Oxytocin signaling pathway	69/912	209/7206	6.44304798309e-15
ko04725	Cholinergic synapse	57/912	160/7206	3.98699473175e-14
ko04024	cAMP signaling pathway	81/912	279/7206	1.07308579174e-13
ko04911	Insulin secretion	46/912	117/7206	2.00037168449e-13
ko04721	Synaptic vesicle cycle	36/912	80/7206	7.1900426164e-13
ko04261	Adrenergic signaling in cardiomyocytes	64/912	205/7206	1.75617243364e-12
ko05031	Amphetamine addiction	35/912	91/7206	3.26869769157e-10
ko04720	Long-term potentiation	35/912	99/7206	4.59168871652e-09
ko04742	Taste transduction	26/912	61/7206	4.88121911788e-09
ko04970	Salivary secretion	33/912	95/7206	2.09712140659e-08
ko04022	cGMP-PKG signaling pathway	57/912	216/7206	3.02948213069e-08
ko04744	Phototransduction	18/912	36/7206	5.72119050495e-08
ko04726	Serotonergic synapse	41/912	137/7206	6.35083332496e-08
ko04260	Cardiac muscle contraction	32/912	98/7206	1.79850198106e-07
ko04060	Cytokine-cytokine receptor interaction	4/912	191/7206	2.15038155497e-07
ko05203	Viral carcinogenesis	10/912	277/7206	2.56491995609e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	26/912	74/7206	5.14796333881e-07
ko03010	Ribosome	1/912	129/7206	7.16723673316e-07
ko03040	Spliceosome	2/912	145/7206	9.27855025373e-07
ko05030	Cocaine addiction	25/912	73/7206	1.47309342668e-06
ko04971	Gastric acid secretion	30/912	98/7206	2.02983526221e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/912	79/7206	2.15556727718e-06
ko05168	Herpes simplex infection	5/912	182/7206	4.07591180439e-06
ko04010	MAPK signaling pathway	69/912	321/7206	6.34247949538e-06
ko04740	Olfactory transduction	25/912	80/7206	9.57598179548e-06
ko04730	Long-term depression	24/912	78/7206	1.92671160631e-05
ko04745	Phototransduction - fly	15/912	38/7206	2.78187671593e-05
ko05322	Systemic lupus erythematosus	4/912	151/7206	3.05108934923e-05
ko04925	Aldosterone synthesis and secretion	29/912	105/7206	3.73784888403e-05
ko05164	Influenza A	6/912	167/7206	8.13439351025e-05
ko04120	Ubiquitin mediated proteolysis	4/912	138/7206	8.60879589644e-05
ko04964	Proximal tubule bicarbonate reclamation	12/912	29/7206	0.000103446707723
ko04514	Cell adhesion molecules (CAMs)	32/912	130/7206	0.000152105629148
ko04621	NOD-like receptor signaling pathway	6/912	157/7206	0.000226427556746
ko04550	Signaling pathways regulating pluripotency of stem cells	7/912	165/7206	0.000333889682208
ko04110	Cell cycle	6/912	145/7206	0.000880714970375
ko03013	RNA transport	8/912	166/7206	0.00125327592826
ko04972	Pancreatic secretion	26/912	111/7206	0.00139901739563
ko05161	Hepatitis B	9/912	173/7206	0.00161403146178
ko05410	Hypertrophic cardiomyopathy (HCM)	24/912	100/7206	0.00201349622085
ko04924	Renin secretion	21/912	86/7206	0.00271359884616
ko04930	Type II diabetes mellitus	15/912	54/7206	0.0028524938029
ko05166	HTLV-I infection	21/912	292/7206	0.00292548290762
ko05162	Measles	5/912	120/7206	0.00319185197581
ko04630	Jak-STAT signaling pathway	6/912	132/7206	0.00324115676809
ko04610	Complement and coagulation cascades	2/912	79/7206	0.00324171757021
ko03008	Ribosome biogenesis in eukaryotes	2/912	79/7206	0.00324171757021
ko04960	Aldosterone-regulated sodium reabsorption	12/912	41/7206	0.003715827871
ko05414	Dilated cardiomyopathy	25/912	112/7206	0.00380429853992
ko04371	Apelin signaling pathway	36/912	177/7206	0.00387639063394
ko05169	Epstein-Barr virus infection	13/912	206/7206	0.00388473255889
ko04350	TGF-beta signaling pathway	4/912	103/7206	0.00411736747778
ko00710	Carbon fixation in photosynthetic organisms	9/912	27/7206	0.00447602794978
ko04626	Plant-pathogen interaction	7/912	18/7206	0.00456266265914
ko04973	Carbohydrate digestion and absorption	12/912	42/7206	0.0046164877692
ko04141	Protein processing in endoplasmic reticulum	11/912	184/7206	0.00463715097375
ko05140	Leishmaniasis	2/912	75/7206	0.00464872447933
ko01230	Biosynthesis of amino acids	20/912	85/7206	0.00478392809359
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/912	14/7206	0.00492352660141
ko05215	Prostate cancer	5/912	111/7206	0.00588464430091
ko05200	Pathways in cancer	43/912	492/7206	0.0060377235912
ko04360	Axon guidance	44/912	233/7206	0.00650214312878
ko05205	Proteoglycans in cancer	20/912	271/7206	0.00666426605754
ko04214	Apoptosis - fly	2/912	72/7206	0.00674077351482
ko05010	Alzheimer's disease	39/912	202/7206	0.00688416990855
ko00010	Glycolysis / Gluconeogenesis	18/912	74/7206	0.00713533271585
ko00471	D-Glutamine and D-glutamate metabolism	3/912	4/7206	0.00732032034766
ko04064	NF-kappa B signaling pathway	4/912	96/7206	0.00801817387488
ko04150	mTOR signaling pathway	12/912	184/7206	0.00938172459288
ko04915	Estrogen signaling pathway	27/912	131/7206	0.0108976520699
ko04072	Phospholipase D signaling pathway	37/912	197/7206	0.012109134829
ko04978	Mineral absorption	11/912	40/7206	0.0133464938324
ko04922	Glucagon signaling pathway	26/912	128/7206	0.0147618742932
ko04612	Antigen processing and presentation	3/912	77/7206	0.0150928458066
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/912	59/7206	0.0167014156575
ko00240	Pyrimidine metabolism	6/912	110/7206	0.0198501158216
ko04330	Notch signaling pathway	2/912	62/7206	0.0200296614007
ko04070	Phosphatidylinositol signaling system	23/912	112/7206	0.020564763103
ko04115	p53 signaling pathway	3/912	74/7206	0.0212319608611
ko04657	IL-17 signaling pathway	4/912	87/7206	0.021635107102
ko00250	Alanine, aspartate and glutamate metabolism	10/912	38/7206	0.0228110115277
ko04210	Apoptosis	13/912	180/7206	0.0230918052823
ko00512	Mucin type O-glycan biosynthesis	8/912	29/7206	0.0239289033818
ko04142	Lysosome	10/912	151/7206	0.0250084903495
ko03420	Nucleotide excision repair	1/912	46/7206	0.0250470570775
ko00220	Arginine biosynthesis	7/912	24/7206	0.0251920293015
ko04750	Inflammatory mediator regulation of TRP channels	24/912	122/7206	0.0267818904806
ko04014	Ras signaling pathway	48/912	279/7206	0.0269524033764
ko04976	Bile secretion	17/912	80/7206	0.0269561038672
ko00680	Methane metabolism	9/912	34/7206	0.0321769086814
ko04510	Focal adhesion	20/912	240/7206	0.0382129574474
ko05321	Inflammatory bowel disease (IBD)	2/912	56/7206	0.041141458864
ko05217	Basal cell carcinoma	3/912	68/7206	0.0416937380342