ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	75/693	145/7206	6.21721875756e-39
ko03030	DNA replication	26/693	38/7206	2.07296269224e-18
ko04080	Neuroactive ligand-receptor interaction	1/693	423/7206	7.42746623867e-18
ko03008	Ribosome biogenesis in eukaryotes	35/693	79/7206	6.13930709794e-16
ko03013	RNA transport	47/693	166/7206	3.66511802417e-12
ko04110	Cell cycle	43/693	145/7206	5.73465205532e-12
ko04111	Cell cycle - yeast	31/693	90/7206	8.32368925408e-11
ko03410	Base excision repair	19/693	38/7206	2.2866302878e-10
ko04020	Calcium signaling pathway	2/693	265/7206	9.66920491075e-10
ko03015	mRNA surveillance pathway	30/693	93/7206	1.04490375899e-09
ko03050	Proteasome	22/693	54/7206	1.22387133321e-09
ko04144	Endocytosis	6/693	342/7206	4.51462820427e-09
ko00240	Pyrimidine metabolism	31/693	110/7206	2.11625982974e-08
ko03420	Nucleotide excision repair	18/693	46/7206	8.45153546083e-08
ko03430	Mismatch repair	12/693	22/7206	1.49032870368e-07
ko05217	Basal cell carcinoma	22/693	68/7206	1.70383970927e-07
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/693	182/7206	2.78913777637e-06
ko04062	Chemokine signaling pathway	3/693	201/7206	4.38451598551e-06
ko04113	Meiosis - yeast	20/693	70/7206	5.48392689289e-06
ko04550	Signaling pathways regulating pluripotency of stem cells	35/693	165/7206	5.70977296869e-06
ko04723	Retrograde endocannabinoid signaling	2/693	175/7206	6.1250625175e-06
ko04060	Cytokine-cytokine receptor interaction	3/693	191/7206	9.1517099648e-06
ko04726	Serotonergic synapse	1/693	137/7206	2.52099957947e-05
ko05169	Epstein-Barr virus infection	39/693	206/7206	3.24574915561e-05
ko03020	RNA polymerase	11/693	29/7206	4.11412749719e-05
ko05202	Transcriptional misregulation in cancer	36/693	188/7206	4.55516811081e-05
ko04921	Oxytocin signaling pathway	5/693	209/7206	6.43459770654e-05
ko04725	Cholinergic synapse	3/693	160/7206	0.000185382342948
ko04072	Phospholipase D signaling pathway	5/693	197/7206	0.000185403445356
ko04950	Maturity onset diabetes of the young	10/693	29/7206	0.000232777607885
ko04070	Phosphatidylinositol signaling system	1/693	112/7206	0.000270239122152
ko00230	Purine metabolism	35/693	194/7206	0.000272111457323
ko04022	cGMP-PKG signaling pathway	7/693	216/7206	0.000399478698985
ko04727	GABAergic synapse	1/693	110/7206	0.000428497716176
ko04371	Apelin signaling pathway	5/693	177/7206	0.00068521474476
ko03460	Fanconi anemia pathway	13/693	51/7206	0.000812127071608
ko04971	Gastric acid secretion	1/693	98/7206	0.000864550118433
ko04340	Hedgehog signaling pathway	14/693	58/7206	0.000931577564316
ko04713	Circadian entrainment	3/693	136/7206	0.0010633921617
ko04024	cAMP signaling pathway	12/693	279/7206	0.00121063740348
ko04310	Wnt signaling pathway	31/693	181/7206	0.00126888701378
ko03440	Homologous recombination	11/693	41/7206	0.00128439120331
ko04970	Salivary secretion	1/693	95/7206	0.0012845313329
ko04010	MAPK signaling pathway	15/693	321/7206	0.00129032564385
ko04390	Hippo signaling pathway	32/693	188/7206	0.0014902139769
ko05224	Breast cancer	30/693	174/7206	0.00153727315375
ko04330	Notch signaling pathway	14/693	62/7206	0.00186084521108
ko04712	Circadian rhythm - plant	4/693	7/7206	0.00234123080516
ko04014	Ras signaling pathway	13/693	279/7206	0.00255103235823
ko04662	B cell receptor signaling pathway	1/693	88/7206	0.00286762235206
ko04920	Adipocytokine signaling pathway	1/693	89/7206	0.0029665041502
ko00562	Inositol phosphate metabolism	1/693	89/7206	0.0029665041502
ko04912	GnRH signaling pathway	3/693	122/7206	0.00304527776441
ko04621	NOD-like receptor signaling pathway	5/693	157/7206	0.00359869457191
ko04925	Aldosterone synthesis and secretion	2/693	105/7206	0.00383426561786
ko04138	Autophagy - yeast	1/693	81/7206	0.00407941547425
ko05100	Bacterial invasion of epithelial cells	2/693	99/7206	0.00532445163792
ko00564	Glycerophospholipid metabolism	2/693	99/7206	0.00532445163792
ko04923	Regulation of lipolysis in adipocytes	1/693	77/7206	0.00598715352495
ko04730	Long-term depression	1/693	78/7206	0.00600808684941
ko04610	Complement and coagulation cascades	1/693	79/7206	0.00609741002321
ko04740	Olfactory transduction	1/693	80/7206	0.00625650638894
ko04630	Jak-STAT signaling pathway	4/693	132/7206	0.00659355845916
ko05414	Dilated cardiomyopathy	3/693	112/7206	0.0087181587926
ko04218	Cellular senescence	28/693	177/7206	0.00908432725394
ko04722	Neurotrophin signaling pathway	6/693	160/7206	0.00918170045308
ko04350	TGF-beta signaling pathway	18/693	103/7206	0.0107977185334
ko04146	Peroxisome	2/693	89/7206	0.0108340829706
ko05120	Epithelial cell signaling in Helicobacter pylori infection	2/693	92/7206	0.0111963524854
ko04270	Vascular smooth muscle contraction	6/693	154/7206	0.0121180059094
ko03320	PPAR signaling pathway	1/693	69/7206	0.0128570637985
ko04924	Renin secretion	2/693	86/7206	0.0155172225869
ko04911	Insulin secretion	4/693	117/7206	0.0170199838841
ko04612	Antigen processing and presentation	14/693	77/7206	0.0176874320669
ko05166	HTLV-I infection	40/693	292/7206	0.0195266042446
ko04976	Bile secretion	2/693	80/7206	0.0219708714958
ko04015	Rap1 signaling pathway	16/693	278/7206	0.0224531803397
ko01200	Carbon metabolism	5/693	128/7206	0.0226606074451
ko04922	Glucagon signaling pathway	5/693	128/7206	0.0226606074451
ko04728	Dopaminergic synapse	9/693	185/7206	0.0226628646149
ko05142	Chagas disease (American trypanosomiasis)	5/693	130/7206	0.0229807697977
ko05211	Renal cell carcinoma	3/693	96/7206	0.0232167661516
ko04915	Estrogen signaling pathway	5/693	131/7206	0.0233118352069
ko05132	Salmonella infection	3/693	98/7206	0.0234113685926
ko04260	Cardiac muscle contraction	3/693	98/7206	0.0234113685926
ko04720	Long-term potentiation	3/693	99/7206	0.0237365969368
ko05146	Amoebiasis	3/693	99/7206	0.0237365969368
ko05410	Hypertrophic cardiomyopathy (HCM)	3/693	100/7206	0.0242145817976
ko04810	Regulation of actin cytoskeleton	15/693	264/7206	0.0251602088036
ko05222	Small cell lung cancer	15/693	89/7206	0.0282068797361
ko04913	Ovarian steroidogenesis	1/693	63/7206	0.028426920828
ko00561	Glycerolipid metabolism	1/693	63/7206	0.028426920828
ko00600	Sphingolipid metabolism	1/693	63/7206	0.028426920828
ko04141	Protein processing in endoplasmic reticulum	9/693	184/7206	0.0300558711447
ko04972	Pancreatic secretion	4/693	111/7206	0.0327760147626
ko03022	Basal transcription factors	9/693	44/7206	0.0335167666483
ko00670	One carbon pool by folate	5/693	20/7206	0.0371129674355
ko04380	Osteoclast differentiation	6/693	134/7206	0.0381412853747
ko05231	Choline metabolism in cancer	6/693	134/7206	0.0381412853747
ko03018	RNA degradation	14/693	84/7206	0.0381781081946
ko04931	Insulin resistance	6/693	137/7206	0.0388128738633
ko04961	Endocrine and other factor-regulated calcium reabsorption	1/693	59/7206	0.0416016982395
ko04071	Sphingolipid signaling pathway	8/693	162/7206	0.0421251320114
ko05030	Cocaine addiction	2/693	73/7206	0.0440996278774
ko04510	Focal adhesion	14/693	240/7206	0.0443732545471
ko05140	Leishmaniasis	2/693	75/7206	0.0454334847535
ko05322	Systemic lupus erythematosus	22/693	151/7206	0.0490771804904