ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	35/689	56/7206	1.79813717948e-22
ko04724	Glutamatergic synapse	58/689	152/7206	7.63826484661e-22
ko04080	Neuroactive ligand-receptor interaction	104/689	423/7206	6.36185051741e-21
ko04728	Dopaminergic synapse	57/689	185/7206	1.92857341945e-16
ko04721	Synaptic vesicle cycle	35/689	80/7206	8.29306347403e-16
ko05032	Morphine addiction	39/689	110/7206	8.1097624176e-14
ko04713	Circadian entrainment	43/689	136/7206	4.11323450085e-13
ko04727	GABAergic synapse	38/689	110/7206	4.3887232081e-13
ko04723	Retrograde endocannabinoid signaling	47/689	175/7206	2.32503847513e-11
ko04024	cAMP signaling pathway	62/689	279/7206	1.12422630237e-10
ko04725	Cholinergic synapse	42/689	160/7206	6.04749715169e-10
ko04911	Insulin secretion	34/689	117/7206	1.54858189538e-09
ko05014	Amyotrophic lateral sclerosis (ALS)	25/689	74/7206	8.02825677436e-09
ko05031	Amphetamine addiction	27/689	91/7206	4.72445547141e-08
ko05030	Cocaine addiction	23/689	73/7206	1.39106309417e-07
ko04514	Cell adhesion molecules (CAMs)	32/689	130/7206	3.48600944362e-07
ko04261	Adrenergic signaling in cardiomyocytes	43/689	205/7206	6.91344693093e-07
ko04720	Long-term potentiation	25/689	99/7206	4.09198344383e-06
ko03040	Spliceosome	1/689	145/7206	1.12344649165e-05
ko04360	Axon guidance	44/689	233/7206	1.14715240269e-05
ko05203	Viral carcinogenesis	8/689	277/7206	2.33657769485e-05
ko04742	Taste transduction	17/689	61/7206	3.65561553858e-05
ko04060	Cytokine-cytokine receptor interaction	4/689	191/7206	5.25642124071e-05
ko04744	Phototransduction	12/689	36/7206	7.66253113734e-05
ko04726	Serotonergic synapse	28/689	137/7206	9.18556788224e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/689	14/7206	0.000133432522465
ko05168	Herpes simplex infection	4/689	182/7206	0.000161441885378
ko04120	Ubiquitin mediated proteolysis	2/689	138/7206	0.000192311615756
ko04970	Salivary secretion	21/689	95/7206	0.000258738187293
ko04010	MAPK signaling pathway	51/689	321/7206	0.000285976401962
ko03013	RNA transport	4/689	166/7206	0.000436759330448
ko04966	Collecting duct acid secretion	9/689	26/7206	0.000444246676892
ko04020	Calcium signaling pathway	43/689	265/7206	0.000575179232021
ko04350	TGF-beta signaling pathway	1/689	103/7206	0.000586814096299
ko04730	Long-term depression	17/689	78/7206	0.0012846897027
ko05164	Influenza A	5/689	167/7206	0.00190157978641
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/689	182/7206	0.00193612294049
ko04972	Pancreatic secretion	21/689	111/7206	0.00277263768824
ko04022	cGMP-PKG signaling pathway	34/689	216/7206	0.00313190687993
ko05162	Measles	3/689	120/7206	0.00433066663908
ko05205	Proteoglycans in cancer	13/689	271/7206	0.00433988143379
ko04141	Protein processing in endoplasmic reticulum	7/689	184/7206	0.00481349395083
ko05322	Systemic lupus erythematosus	5/689	151/7206	0.00484393317037
ko03008	Ribosome biogenesis in eukaryotes	1/689	79/7206	0.00606194664221
ko04140	Autophagy - animal	6/689	164/7206	0.00667033234623
ko04921	Oxytocin signaling pathway	32/689	209/7206	0.00804921023513
ko04971	Gastric acid secretion	18/689	98/7206	0.00812375067696
ko04621	NOD-like receptor signaling pathway	6/689	157/7206	0.0089321077703
ko01200	Carbon metabolism	4/689	128/7206	0.00909578786127
ko04214	Apoptosis - fly	1/689	72/7206	0.0134340870534
ko04540	Gap junction	21/689	128/7206	0.0139830959783
ko04915	Estrogen signaling pathway	21/689	131/7206	0.0158647719536
ko05169	Epstein-Barr virus infection	10/689	206/7206	0.0159823775168
ko05110	Vibrio cholerae infection	12/689	63/7206	0.0165935930175
ko00512	Mucin type O-glycan biosynthesis	7/689	29/7206	0.0170458701425
ko05120	Epithelial cell signaling in Helicobacter pylori infection	16/689	92/7206	0.0182776170657
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/689	79/7206	0.0197748089539
ko04740	Olfactory transduction	14/689	80/7206	0.0213089044934
ko04137	Mitophagy - animal	2/689	82/7206	0.0220596485598
ko03018	RNA degradation	2/689	84/7206	0.0227368348121
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/689	59/7206	0.0249746369429
ko05166	HTLV-I infection	17/689	292/7206	0.0250301780879
ko05161	Hepatitis B	8/689	173/7206	0.0250346622448
ko00330	Arginine and proline metabolism	1/689	61/7206	0.0274680371941
ko00561	Glycerolipid metabolism	1/689	63/7206	0.0282190843551
ko04640	Hematopoietic cell lineage	1/689	64/7206	0.0289940312733
ko04391	Hippo signaling pathway - fly	15/689	90/7206	0.02899426374
ko04612	Antigen processing and presentation	2/689	77/7206	0.0311476537177
ko00240	Pyrimidine metabolism	4/689	110/7206	0.03209384119
ko04064	NF-kappa B signaling pathway	3/689	96/7206	0.0334474509163
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/689	8/7206	0.03379340668
ko04014	Ras signaling pathway	37/689	279/7206	0.0374327680706
ko05206	MicroRNAs in cancer	9/689	177/7206	0.038030570633
ko04924	Renin secretion	14/689	86/7206	0.0412545427415
ko04146	Peroxisome	3/689	89/7206	0.0446257290781
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	4/689	15/7206	0.048152320863