ko pathway ratio_in_study ratio_in_pop p_value ko03030 DNA replication 24/186 38/7206 1.1997265637e-29 ko03460 Fanconi anemia pathway 20/186 51/7206 2.38485174865e-19 ko04110 Cell cycle 29/186 145/7206 2.0496753294e-18 ko03430 Mismatch repair 13/186 22/7206 6.03166854811e-16 ko03440 Homologous recombination 16/186 41/7206 1.19315485685e-15 ko03420 Nucleotide excision repair 14/186 46/7206 4.16180941753e-12 ko03410 Base excision repair 13/186 38/7206 4.57444159564e-12 ko04111 Cell cycle - yeast 18/186 90/7206 8.50672845819e-12 ko00240 Pyrimidine metabolism 17/186 110/7206 2.28643165382e-09 ko04113 Meiosis - yeast 12/186 70/7206 1.76533470778e-07 ko04218 Cellular senescence 16/186 177/7206 1.1829727251e-05 ko05222 Small cell lung cancer 11/186 89/7206 1.59411962119e-05 ko05166 HTLV-I infection 19/186 292/7206 0.000177836198252 ko03040 Spliceosome 12/186 145/7206 0.000346531254548 ko04115 p53 signaling pathway 8/186 74/7206 0.000595467893075 ko05212 Pancreatic cancer 8/186 83/7206 0.00127948282227 ko05219 Bladder cancer 6/186 48/7206 0.0013589733063 ko00230 Purine metabolism 13/186 194/7206 0.0014704006865 ko05161 Hepatitis B 12/186 173/7206 0.00166294620123 ko05215 Prostate cancer 9/186 111/7206 0.00219833783724 ko03450 Non-homologous end-joining 3/186 15/7206 0.00612380372933 ko05223 Non-small cell lung cancer 6/186 66/7206 0.00686645438377 ko04024 cAMP signaling pathway 1/186 279/7206 0.0106365661082 ko01522 Endocrine resistance 8/186 124/7206 0.0146362840667 ko04020 Calcium signaling pathway 1/186 265/7206 0.0155631374831 ko05214 Glioma 6/186 79/7206 0.0159737049063 ko05203 Viral carcinogenesis 14/186 277/7206 0.0175372446838 ko04010 MAPK signaling pathway 2/186 321/7206 0.0177742879419 ko04510 Focal adhesion 1/186 240/7206 0.0218350897277 ko05218 Melanoma 6/186 85/7206 0.0221629375863 ko05220 Chronic myeloid leukemia 6/186 85/7206 0.0221629375863 ko05210 Colorectal cancer 6/186 86/7206 0.0233318482968 ko03013 RNA transport 9/186 166/7206 0.0400045219883 ko01524 Platinum drug resistance 5/186 76/7206 0.0460316078734 ko04022 cGMP-PKG signaling pathway 1/186 216/7206 0.0460956291393 ko05206 MicroRNAs in cancer 9/186 177/7206 0.0485445915182