ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 22/275 79/7206 7.56161384185e-14 ko04974 Protein digestion and absorption 19/275 96/7206 2.4081542636e-09 ko04976 Bile secretion 17/275 80/7206 5.48790397999e-09 ko00140 Steroid hormone biosynthesis 12/275 41/7206 2.20633704007e-08 ko00380 Tryptophan metabolism 12/275 50/7206 2.49225161199e-07 ko00983 Drug metabolism - other enzymes 11/275 42/7206 3.05589279868e-07 ko00830 Retinol metabolism 11/275 42/7206 3.05589279868e-07 ko00591 Linoleic acid metabolism 8/275 22/7206 8.1578027418e-07 ko00590 Arachidonic acid metabolism 11/275 52/7206 3.06802745291e-06 ko00120 Primary bile acid biosynthesis 7/275 20/7206 5.52376208572e-06 ko05204 Chemical carcinogenesis 10/275 48/7206 1.00643357271e-05 ko00260 Glycine, serine and threonine metabolism 10/275 48/7206 1.00643357271e-05 ko00350 Tyrosine metabolism 8/275 33/7206 2.45524020014e-05 ko04975 Fat digestion and absorption 8/275 35/7206 3.89434680587e-05 ko05150 Staphylococcus aureus infection 8/275 36/7206 4.84342716369e-05 ko00592 alpha-Linolenic acid metabolism 6/275 19/7206 5.21513241653e-05 ko04972 Pancreatic secretion 14/275 111/7206 7.53416780832e-05 ko02010 ABC transporters 8/275 39/7206 8.91407883045e-05 ko04146 Peroxisome 12/275 89/7206 0.000128871778469 ko05200 Pathways in cancer 5/275 492/7206 0.00020585780783 ko00643 Styrene degradation 3/275 4/7206 0.000213760042269 ko00360 Phenylalanine metabolism 5/275 17/7206 0.000330972955107 ko00040 Pentose and glucuronate interconversions 6/275 26/7206 0.00035315962538 ko00982 Drug metabolism - cytochrome P450 7/275 37/7206 0.000420062769897 ko04614 Renin-angiotensin system 5/275 18/7206 0.000444095521438 ko00232 Caffeine metabolism 3/275 5/7206 0.000519292820141 ko00980 Metabolism of xenobiotics by cytochrome P450 7/275 40/7206 0.000689737083591 ko04978 Mineral absorption 7/275 40/7206 0.000689737083591 ko00100 Steroid biosynthesis 5/275 21/7206 0.000960016699407 ko03320 PPAR signaling pathway 9/275 69/7206 0.00114363892838 ko00053 Ascorbate and aldarate metabolism 5/275 22/7206 0.0012040854908 ko04144 Endocytosis 3/275 342/7206 0.0012742198929 ko05166 HTLV-I infection 2/275 292/7206 0.00151389883273 ko04080 Neuroactive ligand-receptor interaction 5/275 423/7206 0.00152229572628 ko00860 Porphyrin and chlorophyll metabolism 6/275 34/7206 0.00159625063294 ko00340 Histidine metabolism 5/275 25/7206 0.00221193088439 ko04973 Carbohydrate digestion and absorption 6/275 42/7206 0.00482467206036 ko00950 Isoquinoline alkaloid biosynthesis 3/275 10/7206 0.00540351608639 ko00071 Fatty acid degradation 6/275 45/7206 0.00681073965064 ko00330 Arginine and proline metabolism 7/275 61/7206 0.00817281981266 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/275 4/7206 0.00827400570607 ko00640 Propanoate metabolism 5/275 34/7206 0.00875922293866 ko04977 Vitamin digestion and absorption 4/275 22/7206 0.00881474882006 ko00500 Starch and sucrose metabolism 5/275 35/7206 0.0099081082995 ko04141 Protein processing in endoplasmic reticulum 1/275 184/7206 0.0104035674253 ko04390 Hippo signaling pathway 1/275 188/7206 0.0105845561002 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/275 5/7206 0.0134438142968 ko04151 PI3K-Akt signaling pathway 6/275 390/7206 0.0134989800613 ko04723 Retrograde endocannabinoid signaling 1/275 175/7206 0.0151080626107 ko04217 Necroptosis 1/275 178/7206 0.0153698064832 ko04310 Wnt signaling pathway 1/275 181/7206 0.0158407261043 ko04212 Longevity regulating pathway - worm 8/275 87/7206 0.0175258127454 ko05133 Pertussis 8/275 87/7206 0.0175258127454 ko05016 Huntington's disease 2/275 215/7206 0.0177888201043 ko00362 Benzoate degradation 2/275 6/7206 0.0196610816757 ko03013 RNA transport 1/275 166/7206 0.0219657210815 ko04010 MAPK signaling pathway 5/275 321/7206 0.0250412578232 ko01212 Fatty acid metabolism 6/275 60/7206 0.026095527024 ko00620 Pyruvate metabolism 5/275 46/7206 0.0298450776662 ko04913 Ovarian steroidogenesis 6/275 63/7206 0.0322457610698 ko00561 Glycerolipid metabolism 6/275 63/7206 0.0322457610698 ko00270 Cysteine and methionine metabolism 5/275 47/7206 0.0323948109047 ko04725 Cholinergic synapse 1/275 160/7206 0.032874636139 ko00740 Riboflavin metabolism 2/275 8/7206 0.0348954942973 ko00052 Galactose metabolism 4/275 33/7206 0.0355873295449 ko05203 Viral carcinogenesis 4/275 277/7206 0.0356612971551 ko04360 Axon guidance 3/275 233/7206 0.0359510384611 ko05034 Alcoholism 3/275 238/7206 0.0365745496988 ko00401 Novobiocin biosynthesis 1/275 1/7206 0.0381626422426 ko00410 beta-Alanine metabolism 4/275 35/7206 0.0429394171508 ko01230 Biosynthesis of amino acids 7/275 85/7206 0.0429725068925