ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	164/994	423/7206	3.25432804414e-40
ko04724	Glutamatergic synapse	81/994	152/7206	1.94679267737e-31
ko05033	Nicotine addiction	46/994	56/7206	9.49901936703e-31
ko05032	Morphine addiction	65/994	110/7206	6.2726578782e-29
ko04727	GABAergic synapse	64/994	110/7206	5.90384756511e-28
ko04728	Dopaminergic synapse	78/994	185/7206	7.19909034499e-22
ko04723	Retrograde endocannabinoid signaling	74/994	175/7206	6.93492864324e-21
ko04713	Circadian entrainment	63/994	136/7206	1.96377674325e-20
ko04725	Cholinergic synapse	66/994	160/7206	4.69023419965e-18
ko04744	Phototransduction	26/994	36/7206	2.04088772073e-15
ko04024	cAMP signaling pathway	89/994	279/7206	2.29658868642e-15
ko04721	Synaptic vesicle cycle	40/994	80/7206	7.98058914326e-15
ko04742	Taste transduction	33/994	61/7206	9.93857865252e-14
ko04726	Serotonergic synapse	53/994	137/7206	2.30192435392e-13
ko04020	Calcium signaling pathway	81/994	265/7206	5.51373518099e-13
ko04911	Insulin secretion	46/994	117/7206	4.66643714077e-12
ko04261	Adrenergic signaling in cardiomyocytes	65/994	205/7206	1.99471976973e-11
ko04921	Oxytocin signaling pathway	65/994	209/7206	6.09963847127e-11
ko05031	Amphetamine addiction	34/994	91/7206	1.38448535317e-08
ko03040	Spliceosome	1/994	145/7206	1.4403680421e-08
ko05030	Cocaine addiction	28/994	73/7206	1.38143537387e-07
ko04720	Long-term potentiation	34/994	99/7206	1.54381873376e-07
ko04970	Salivary secretion	33/994	95/7206	1.72889514966e-07
ko05203	Viral carcinogenesis	12/994	277/7206	2.69984094695e-07
ko04072	Phospholipase D signaling pathway	53/994	197/7206	8.81008614705e-07
ko04514	Cell adhesion molecules (CAMs)	38/994	130/7206	3.81987145591e-06
ko05322	Systemic lupus erythematosus	4/994	151/7206	3.98994041361e-06
ko04925	Aldosterone synthesis and secretion	32/994	105/7206	9.56507609837e-06
ko04060	Cytokine-cytokine receptor interaction	8/994	191/7206	1.60860676619e-05
ko05164	Influenza A	6/994	167/7206	1.88961684073e-05
ko04740	Olfactory transduction	26/994	80/7206	2.04134748963e-05
ko04010	MAPK signaling pathway	71/994	321/7206	3.07278368547e-05
ko04022	cGMP-PKG signaling pathway	52/994	216/7206	3.39531170158e-05
ko04972	Pancreatic secretion	32/994	111/7206	3.52885250482e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	24/994	74/7206	4.67718102652e-05
ko03013	RNA transport	7/994	166/7206	8.42199415455e-05
ko04070	Phosphatidylinositol signaling system	31/994	112/7206	8.59941476071e-05
ko05205	Proteoglycans in cancer	17/994	271/7206	9.89575329588e-05
ko04260	Cardiac muscle contraction	28/994	98/7206	0.000153409420243
ko04971	Gastric acid secretion	28/994	98/7206	0.000153409420243
ko05168	Herpes simplex infection	9/994	182/7206	0.000176863241197
ko04610	Complement and coagulation cascades	1/994	79/7206	0.000204483837562
ko04110	Cell cycle	6/994	145/7206	0.000211923887808
ko05169	Epstein-Barr virus infection	12/994	206/7206	0.000302997490993
ko04730	Long-term depression	23/994	78/7206	0.000348097143755
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/994	79/7206	0.000385314035934
ko04120	Ubiquitin mediated proteolysis	6/994	138/7206	0.000411577628846
ko05162	Measles	5/994	120/7206	0.000754541022866
ko04745	Phototransduction - fly	13/994	38/7206	0.00115771679117
ko04915	Estrogen signaling pathway	32/994	131/7206	0.00118349380368
ko05414	Dilated cardiomyopathy	28/994	112/7206	0.00130155983017
ko03008	Ribosome biogenesis in eukaryotes	2/994	79/7206	0.00145691569423
ko04976	Bile secretion	22/994	80/7206	0.00152346409131
ko05140	Leishmaniasis	2/994	75/7206	0.00208064065316
ko04621	NOD-like receptor signaling pathway	9/994	157/7206	0.00210828077148
ko04141	Protein processing in endoplasmic reticulum	12/994	184/7206	0.00230161739334
ko05161	Hepatitis B	11/994	173/7206	0.00246116264574
ko04014	Ras signaling pathway	56/994	279/7206	0.00331281795534
ko04360	Axon guidance	48/994	233/7206	0.00359226161976
ko04964	Proximal tubule bicarbonate reclamation	10/994	29/7206	0.00397123277635
ko04064	NF-kappa B signaling pathway	4/994	96/7206	0.0040390919426
ko00480	Glutathione metabolism	1/994	55/7206	0.00504487122679
ko04966	Collecting duct acid secretion	9/994	26/7206	0.00602562080395
ko04540	Gap junction	29/994	128/7206	0.00610014296299
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/994	182/7206	0.00628103403418
ko04924	Renin secretion	21/994	86/7206	0.00698236632749
ko04612	Antigen processing and presentation	3/994	77/7206	0.00723559764598
ko05231	Choline metabolism in cancer	30/994	134/7206	0.00731238162748
ko00590	Arachidonic acid metabolism	1/994	52/7206	0.00749594065102
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/994	14/7206	0.00758276753199
ko00240	Pyrimidine metabolism	6/994	110/7206	0.0076387549297
ko00290	Valine, leucine and isoleucine biosynthesis	3/994	4/7206	0.00939090928029
ko04750	Inflammatory mediator regulation of TRP channels	27/994	122/7206	0.011201262645
ko04710	Circadian rhythm	12/994	43/7206	0.0128851966938
ko04371	Apelin signaling pathway	36/994	177/7206	0.0147100496451
ko04630	Jak-STAT signaling pathway	9/994	132/7206	0.0153171241577
ko04930	Type II diabetes mellitus	14/994	54/7206	0.0157971235294
ko05144	Malaria	1/994	45/7206	0.0163354334575
ko00071	Fatty acid degradation	1/994	45/7206	0.0163354334575
ko03420	Nucleotide excision repair	1/994	46/7206	0.0164760931159
ko05321	Inflammatory bowel disease (IBD)	2/994	56/7206	0.0192339065361
ko04923	Regulation of lipolysis in adipocytes	18/994	77/7206	0.0194914919906
ko04146	Peroxisome	5/994	89/7206	0.0199673310296
ko03320	PPAR signaling pathway	3/994	69/7206	0.0208300787561
ko04510	Focal adhesion	21/994	240/7206	0.02181479916
ko04062	Chemokine signaling pathway	39/994	201/7206	0.0224812544241
ko04711	Circadian rhythm - fly	5/994	13/7206	0.0244276500214
ko03022	Basal transcription factors	1/994	44/7206	0.0251001200421
ko05145	Toxoplasmosis	9/994	126/7206	0.0263332813871
ko05410	Hypertrophic cardiomyopathy (HCM)	22/994	100/7206	0.0269272376479
ko05110	Vibrio cholerae infection	15/994	63/7206	0.0270644734308
ko05133	Pertussis	5/994	87/7206	0.0273361228199
ko04640	Hematopoietic cell lineage	3/994	64/7206	0.0286345670864
ko04140	Autophagy - animal	13/994	164/7206	0.0287185873506
ko05016	Huntington's disease	19/994	215/7206	0.0343513684427
ko04658	Th1 and Th2 cell differentiation	6/994	96/7206	0.0352390470695
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/994	59/7206	0.0353459080055
ko05034	Alcoholism	44/994	238/7206	0.0356169051943
ko04217	Necroptosis	15/994	178/7206	0.0359624267262
ko04810	Regulation of actin cytoskeleton	25/994	264/7206	0.0364617387956
ko05166	HTLV-I infection	28/994	292/7206	0.0370610737551
ko03018	RNA degradation	5/994	84/7206	0.0370849056583
ko04918	Thyroid hormone synthesis	19/994	86/7206	0.0387351488774
ko04115	p53 signaling pathway	4/994	74/7206	0.0397827226091
ko00330	Arginine and proline metabolism	3/994	61/7206	0.0400017308002
ko04622	RIG-I-like receptor signaling pathway	3/994	62/7206	0.0402207561339
ko00562	Inositol phosphate metabolism	19/994	89/7206	0.0439640567014