ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04110	Cell cycle	62/439	145/7206	4.83646498637e-38
ko04111	Cell cycle - yeast	44/439	90/7206	3.27474074406e-30
ko03030	DNA replication	30/439	38/7206	4.18033794727e-30
ko04113	Meiosis - yeast	31/439	70/7206	5.99171652393e-20
ko03440	Homologous recombination	23/439	41/7206	4.67098659309e-18
ko03460	Fanconi anemia pathway	25/439	51/7206	1.21602504158e-17
ko03410	Base excision repair	21/439	38/7206	2.08470562204e-16
ko03040	Spliceosome	39/439	145/7206	6.964887147e-16
ko03430	Mismatch repair	16/439	22/7206	1.47175663841e-15
ko03420	Nucleotide excision repair	18/439	46/7206	5.46984636261e-11
ko00240	Pyrimidine metabolism	26/439	110/7206	1.22467661009e-09
ko04144	Endocytosis	1/439	342/7206	1.02793283663e-08
ko05166	HTLV-I infection	42/439	292/7206	1.24123754323e-07
ko04114	Oocyte meiosis	25/439	139/7206	7.82342681743e-07
ko03013	RNA transport	27/439	166/7206	2.20342429799e-06
ko03015	mRNA surveillance pathway	18/439	93/7206	9.74296524808e-06
ko04072	Phospholipase D signaling pathway	1/439	197/7206	0.000104872034127
ko04810	Regulation of actin cytoskeleton	3/439	264/7206	0.000105659362736
ko04115	p53 signaling pathway	14/439	74/7206	0.000122915509748
ko04914	Progesterone-mediated oocyte maturation	17/439	104/7206	0.000160069627511
ko04218	Cellular senescence	24/439	177/7206	0.000181460234256
ko03008	Ribosome biogenesis in eukaryotes	14/439	79/7206	0.000253452159686
ko04723	Retrograde endocannabinoid signaling	1/439	175/7206	0.00032499155723
ko00230	Purine metabolism	25/439	194/7206	0.000338228487262
ko04014	Ras signaling pathway	5/439	279/7206	0.000789479530699
ko05152	Tuberculosis	2/439	187/7206	0.000998436021211
ko04060	Cytokine-cytokine receptor interaction	2/439	191/7206	0.00102356024756
ko04270	Vascular smooth muscle contraction	1/439	154/7206	0.00102484395237
ko05012	Parkinson's disease	1/439	155/7206	0.001025864479
ko04330	Notch signaling pathway	11/439	62/7206	0.00113716792791
ko04022	cGMP-PKG signaling pathway	3/439	216/7206	0.00124963981899
ko04724	Glutamatergic synapse	1/439	152/7206	0.00156495275176
ko05203	Viral carcinogenesis	30/439	277/7206	0.00188257016123
ko04062	Chemokine signaling pathway	3/439	201/7206	0.00246852221083
ko04024	cAMP signaling pathway	6/439	279/7206	0.00297996649691
ko05231	Choline metabolism in cancer	1/439	134/7206	0.00320617785201
ko04726	Serotonergic synapse	1/439	137/7206	0.00324364495809
ko04010	MAPK signaling pathway	8/439	321/7206	0.00383640342694
ko04725	Cholinergic synapse	2/439	160/7206	0.00421012354957
ko04514	Cell adhesion molecules (CAMs)	1/439	130/7206	0.00470893150856
ko00670	One carbon pool by folate	5/439	20/7206	0.0059268288368
ko04912	GnRH signaling pathway	1/439	122/7206	0.00680296543743
ko04750	Inflammatory mediator regulation of TRP channels	1/439	122/7206	0.00680296543743
ko04066	HIF-1 signaling pathway	1/439	123/7206	0.00683273642396
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/439	182/7206	0.00687663950064
ko04015	Rap1 signaling pathway	7/439	278/7206	0.00705228166081
ko04921	Oxytocin signaling pathway	4/439	209/7206	0.00742280478844
ko04910	Insulin signaling pathway	3/439	172/7206	0.00950818148877
ko04371	Apelin signaling pathway	3/439	177/7206	0.0097671109731
ko04911	Insulin secretion	1/439	117/7206	0.0099742247062
ko05222	Small cell lung cancer	12/439	89/7206	0.0109737624367
ko04510	Focal adhesion	6/439	240/7206	0.0131329131326
ko04727	GABAergic synapse	1/439	110/7206	0.0144240102693
ko05032	Morphine addiction	1/439	110/7206	0.0144240102693
ko04380	Osteoclast differentiation	2/439	134/7206	0.0170768936817
ko04713	Circadian entrainment	2/439	136/7206	0.0172045234613
ko04611	Platelet activation	3/439	163/7206	0.018741124389
ko04915	Estrogen signaling pathway	2/439	131/7206	0.0246409197965
ko04261	Adrenergic signaling in cardiomyocytes	5/439	205/7206	0.0248829704342
ko04630	Jak-STAT signaling pathway	2/439	132/7206	0.0249636015614
ko05160	Hepatitis C	3/439	153/7206	0.0253650720675
ko04120	Ubiquitin mediated proteolysis	15/439	138/7206	0.0284306599674
ko04064	NF-kappa B signaling pathway	1/439	96/7206	0.0300640214419
ko04650	Natural killer cell mediated cytotoxicity	1/439	97/7206	0.0302369305357
ko04971	Gastric acid secretion	1/439	98/7206	0.030520271507
ko00564	Glycerophospholipid metabolism	1/439	99/7206	0.0309140355028
ko05146	Amoebiasis	1/439	99/7206	0.0309140355028
ko04620	Toll-like receptor signaling pathway	1/439	100/7206	0.0314183114043
ko01523	Antifolate resistance	5/439	30/7206	0.0330673104734
ko04668	TNF signaling pathway	2/439	120/7206	0.0338209374709
ko05217	Basal cell carcinoma	9/439	68/7206	0.0349883422091
ko05145	Toxoplasmosis	2/439	126/7206	0.0354299935307
ko04151	PI3K-Akt signaling pathway	14/439	390/7206	0.0376185215797
ko04662	B cell receptor signaling pathway	1/439	88/7206	0.0432667340744
ko05120	Epithelial cell signaling in Helicobacter pylori infection	1/439	92/7206	0.0443313777502
ko04530	Tight junction	7/439	228/7206	0.0490115186648