ko pathway ratio_in_study ratio_in_pop p_value ko00590 Arachidonic acid metabolism 6/80 52/7206 2.09975347478e-05 ko04630 Jak-STAT signaling pathway 8/80 132/7206 9.81616807285e-05 ko04659 Th17 cell differentiation 7/80 106/7206 0.000160701486605 ko04060 Cytokine-cytokine receptor interaction 9/80 191/7206 0.000244267423594 ko05321 Inflammatory bowel disease (IBD) 5/80 56/7206 0.000364665165099 ko04658 Th1 and Th2 cell differentiation 6/80 96/7206 0.000649132948607 ko04064 NF-kappa B signaling pathway 6/80 96/7206 0.000649132948607 ko04380 Osteoclast differentiation 7/80 134/7206 0.000675059917385 ko04640 Hematopoietic cell lineage 5/80 64/7206 0.000679236262297 ko05310 Asthma 3/80 17/7206 0.000800964277559 ko05152 Tuberculosis 8/80 187/7206 0.00103971333382 ko00592 alpha-Linolenic acid metabolism 3/80 19/7206 0.00112326044144 ko05140 Leishmaniasis 5/80 75/7206 0.00139827100722 ko04611 Platelet activation 7/80 163/7206 0.00211740283224 ko05340 Primary immunodeficiency 3/80 30/7206 0.0043110619601 ko05150 Staphylococcus aureus infection 3/80 36/7206 0.00722865558644 ko04664 Fc epsilon RI signaling pathway 4/80 77/7206 0.0103279579703 ko05162 Measles 5/80 120/7206 0.010490192186 ko00983 Drug metabolism - other enzymes 3/80 42/7206 0.0110831051141 ko04610 Complement and coagulation cascades 4/80 79/7206 0.0112778521947 ko04662 B cell receptor signaling pathway 4/80 88/7206 0.01624427474 ko04146 Peroxisome 4/80 89/7206 0.0168684428302 ko00120 Primary bile acid biosynthesis 2/80 20/7206 0.0203190906052 ko04650 Natural killer cell mediated cytotoxicity 4/80 97/7206 0.0224052499794 ko00480 Glutathione metabolism 3/80 55/7206 0.0228606551276 ko05416 Viral myocarditis 3/80 55/7206 0.0228606551276 ko00591 Linoleic acid metabolism 2/80 22/7206 0.0243537627373 ko04620 Toll-like receptor signaling pathway 4/80 100/7206 0.0247362816005 ko05330 Allograft rejection 2/80 24/7206 0.0286864744451 ko00561 Glycerolipid metabolism 3/80 63/7206 0.0324990731244 ko00633 Nitrotoluene degradation 1/80 3/7206 0.0329417140559 ko05320 Autoimmune thyroid disease 2/80 29/7206 0.040726369803 ko04136 Autophagy - other 2/80 31/7206 0.0459890018366 ko04666 Fc gamma R-mediated phagocytosis 4/80 122/7206 0.046243249005 ko04217 Necroptosis 5/80 178/7206 0.0473179321399