ko pathway ratio_in_study ratio_in_pop p_value ko04080 Neuroactive ligand-receptor interaction 94/514 423/7206 5.15172930726e-25 ko04724 Glutamatergic synapse 50/514 152/7206 2.47275241612e-21 ko04744 Phototransduction 24/514 36/7206 1.00620985529e-19 ko04727 GABAergic synapse 40/514 110/7206 4.75862431075e-19 ko05033 Nicotine addiction 27/514 56/7206 5.93527444619e-17 ko05032 Morphine addiction 36/514 110/7206 1.44455912403e-15 ko04723 Retrograde endocannabinoid signaling 43/514 175/7206 2.23477580715e-13 ko04713 Circadian entrainment 37/514 136/7206 3.95886462099e-13 ko04728 Dopaminergic synapse 41/514 185/7206 2.9817145583e-11 ko04725 Cholinergic synapse 37/514 160/7206 7.74494063061e-11 ko04740 Olfactory transduction 25/514 80/7206 1.08190869253e-10 ko04742 Taste transduction 21/514 61/7206 4.57942870943e-10 ko04024 cAMP signaling pathway 49/514 279/7206 2.73107539263e-09 ko04911 Insulin secretion 28/514 117/7206 7.38611785646e-09 ko04726 Serotonergic synapse 30/514 137/7206 1.9602929541e-08 ko04721 Synaptic vesicle cycle 20/514 80/7206 5.02181804587e-07 ko04972 Pancreatic secretion 24/514 111/7206 6.73651728724e-07 ko04976 Bile secretion 19/514 80/7206 2.2463203183e-06 ko05031 Amphetamine addiction 20/514 91/7206 4.42159206596e-06 ko04921 Oxytocin signaling pathway 34/514 209/7206 6.68160386654e-06 ko04261 Adrenergic signaling in cardiomyocytes 33/514 205/7206 1.05903272869e-05 ko04925 Aldosterone synthesis and secretion 21/514 105/7206 1.23005913475e-05 ko04970 Salivary secretion 19/514 95/7206 3.18368461879e-05 ko05014 Amyotrophic lateral sclerosis (ALS) 16/514 74/7206 4.94746916105e-05 ko05164 Influenza A 1/514 167/7206 9.6971708749e-05 ko05203 Viral carcinogenesis 5/514 277/7206 0.000106729571312 ko04020 Calcium signaling pathway 36/514 265/7206 0.000139392512861 ko05030 Cocaine addiction 15/514 73/7206 0.000156117603419 ko04720 Long-term potentiation 18/514 99/7206 0.000186136907823 ko05322 Systemic lupus erythematosus 1/514 151/7206 0.000314279341928 ko04730 Long-term depression 15/514 78/7206 0.000336512029331 ko05168 Herpes simplex infection 2/514 182/7206 0.00033983479026 ko03040 Spliceosome 1/514 145/7206 0.000459656015133 ko03013 RNA transport 2/514 166/7206 0.000664383161827 ko04060 Cytokine-cytokine receptor interaction 3/514 191/7206 0.000856334051094 ko04550 Signaling pathways regulating pluripotency of stem cells 2/514 165/7206 0.00102070255828 ko04932 Non-alcoholic fatty liver disease (NAFLD) 3/514 182/7206 0.00118983102136 ko04978 Mineral absorption 9/514 40/7206 0.00165274537222 ko05162 Measles 1/514 120/7206 0.0021102710011 ko00830 Retinol metabolism 9/514 42/7206 0.00237227889587 ko04540 Gap junction 19/514 128/7206 0.00248190545746 ko05016 Huntington's disease 5/514 215/7206 0.00280230511464 ko04110 Cell cycle 2/514 145/7206 0.00286696687615 ko04062 Chemokine signaling pathway 26/514 201/7206 0.00305381908393 ko05166 HTLV-I infection 9/514 292/7206 0.00355209916936 ko04120 Ubiquitin mediated proteolysis 2/514 138/7206 0.00406788539221 ko04971 Gastric acid secretion 15/514 98/7206 0.0044299177923 ko04745 Phototransduction - fly 8/514 38/7206 0.00460088273641 ko04141 Protein processing in endoplasmic reticulum 4/514 184/7206 0.00520460700204 ko05169 Epstein-Barr virus infection 5/514 206/7206 0.00540818658358 ko04974 Protein digestion and absorption 14/514 96/7206 0.00854309285218 ko04924 Renin secretion 13/514 86/7206 0.00916189933084 ko04010 MAPK signaling pathway 35/514 321/7206 0.0104104176985 ko04750 Inflammatory mediator regulation of TRP channels 16/514 122/7206 0.0187839789452 ko02010 ABC transporters 7/514 39/7206 0.0188054565182 ko05215 Prostate cancer 2/514 111/7206 0.0237870590727 ko05224 Breast cancer 5/514 174/7206 0.0242092085414 ko05206 MicroRNAs in cancer 5/514 177/7206 0.0248898883505 ko04260 Cardiac muscle contraction 13/514 98/7206 0.0271163095516 ko05230 Central carbon metabolism in cancer 1/514 81/7206 0.0292704903816 ko03018 RNA degradation 1/514 84/7206 0.0298962739626 ko05220 Chronic myeloid leukemia 1/514 85/7206 0.0304058654826 ko04371 Apelin signaling pathway 20/514 177/7206 0.037237124004 ko05414 Dilated cardiomyopathy 14/514 112/7206 0.0387323616806 ko04150 mTOR signaling pathway 6/514 184/7206 0.0406021792945 ko05130 Pathogenic Escherichia coli infection 1/514 77/7206 0.0425826017225 ko04612 Antigen processing and presentation 1/514 77/7206 0.0425826017225 ko00230 Purine metabolism 21/514 194/7206 0.0477148067775