ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	162/1066	423/7206	6.81458832726e-35
ko04724	Glutamatergic synapse	83/1066	152/7206	5.94703587238e-31
ko05033	Nicotine addiction	45/1066	56/7206	5.73606739721e-28
ko05032	Morphine addiction	65/1066	110/7206	4.08731719687e-27
ko04713	Circadian entrainment	68/1066	136/7206	1.3613427438e-22
ko04727	GABAergic synapse	58/1066	110/7206	6.64740036414e-21
ko04723	Retrograde endocannabinoid signaling	75/1066	175/7206	1.01974738512e-19
ko04725	Cholinergic synapse	70/1066	160/7206	4.49501473843e-19
ko04020	Calcium signaling pathway	95/1066	265/7206	3.50459966586e-18
ko04728	Dopaminergic synapse	75/1066	185/7206	4.93979796251e-18
ko04024	cAMP signaling pathway	95/1066	279/7206	1.90033536696e-16
ko04921	Oxytocin signaling pathway	73/1066	209/7206	2.16556076876e-13
ko04726	Serotonergic synapse	55/1066	137/7206	2.54425211629e-13
ko04911	Insulin secretion	48/1066	117/7206	3.3959512128e-12
ko04742	Taste transduction	30/1066	61/7206	1.9578218886e-10
ko04744	Phototransduction	22/1066	36/7206	2.14365527872e-10
ko04721	Synaptic vesicle cycle	35/1066	80/7206	3.66253242427e-10
ko04720	Long-term potentiation	39/1066	99/7206	1.54365105571e-09
ko04261	Adrenergic signaling in cardiomyocytes	63/1066	205/7206	5.15859703867e-09
ko05031	Amphetamine addiction	36/1066	91/7206	5.77814248471e-09
ko03040	Spliceosome	2/1066	145/7206	4.09490034022e-08
ko03010	Ribosome	1/1066	129/7206	4.69802801406e-08
ko04925	Aldosterone synthesis and secretion	37/1066	105/7206	1.73745560167e-07
ko04022	cGMP-PKG signaling pathway	60/1066	216/7206	4.91854089173e-07
ko03013	RNA transport	5/1066	166/7206	7.08035294322e-07
ko05322	Systemic lupus erythematosus	4/1066	151/7206	1.15490578569e-06
ko05203	Viral carcinogenesis	16/1066	277/7206	2.5320594986e-06
ko04970	Salivary secretion	32/1066	95/7206	3.057293708e-06
ko04072	Phospholipase D signaling pathway	54/1066	197/7206	3.29822774069e-06
ko04710	Circadian rhythm	19/1066	43/7206	3.37521326171e-06
ko04010	MAPK signaling pathway	78/1066	321/7206	3.90586393472e-06
ko05030	Cocaine addiction	26/1066	73/7206	7.65196443921e-06
ko04971	Gastric acid secretion	32/1066	98/7206	8.51424485285e-06
ko04730	Long-term depression	27/1066	78/7206	1.29836085825e-05
ko04110	Cell cycle	5/1066	145/7206	1.43367587264e-05
ko04070	Phosphatidylinositol signaling system	34/1066	112/7206	2.13738333729e-05
ko04972	Pancreatic secretion	33/1066	111/7206	6.26057934988e-05
ko04060	Cytokine-cytokine receptor interaction	11/1066	191/7206	0.000115480701314
ko04612	Antigen processing and presentation	1/1066	77/7206	0.000128605472742
ko04514	Cell adhesion molecules (CAMs)	36/1066	130/7206	0.000139650120016
ko04745	Phototransduction - fly	15/1066	38/7206	0.000174536765477
ko04922	Glucagon signaling pathway	35/1066	128/7206	0.000212371237353
ko04360	Axon guidance	55/1066	233/7206	0.000323781171637
ko04740	Olfactory transduction	24/1066	80/7206	0.000408665410234
ko05014	Amyotrophic lateral sclerosis (ALS)	22/1066	74/7206	0.000829431451839
ko05168	Herpes simplex infection	12/1066	182/7206	0.000940172225789
ko04750	Inflammatory mediator regulation of TRP channels	32/1066	122/7206	0.00110538595375
ko05164	Influenza A	11/1066	167/7206	0.00131163437583
ko04141	Protein processing in endoplasmic reticulum	13/1066	184/7206	0.00154116065669
ko04930	Type II diabetes mellitus	17/1066	54/7206	0.00160292578153
ko04014	Ras signaling pathway	60/1066	279/7206	0.0019247310452
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/1066	79/7206	0.00222799873679
ko04260	Cardiac muscle contraction	26/1066	98/7206	0.00228175734635
ko04540	Gap junction	32/1066	128/7206	0.00229260510728
ko05130	Pathogenic Escherichia coli infection	3/1066	77/7206	0.00338699646846
ko05133	Pertussis	4/1066	87/7206	0.00370602728951
ko04371	Apelin signaling pathway	40/1066	177/7206	0.00504207961655
ko05169	Epstein-Barr virus infection	17/1066	206/7206	0.00523825692646
ko04915	Estrogen signaling pathway	31/1066	131/7206	0.00604496565651
ko04964	Proximal tubule bicarbonate reclamation	10/1066	29/7206	0.00661187115154
ko04711	Circadian rhythm - fly	6/1066	13/7206	0.00697552861447
ko05131	Shigellosis	4/1066	82/7206	0.00732280368783
ko04924	Renin secretion	22/1066	86/7206	0.00850194390781
ko04621	NOD-like receptor signaling pathway	12/1066	157/7206	0.0086343815098
ko05231	Choline metabolism in cancer	31/1066	134/7206	0.009404197645
ko00240	Pyrimidine metabolism	7/1066	110/7206	0.00958668128414
ko05414	Dilated cardiomyopathy	27/1066	112/7206	0.0100066923431
ko04146	Peroxisome	5/1066	89/7206	0.0102439771899
ko04120	Ubiquitin mediated proteolysis	10/1066	138/7206	0.0104343290798
ko00071	Fatty acid degradation	1/1066	45/7206	0.0105909350642
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1066	14/7206	0.0107005954319
ko03420	Nucleotide excision repair	1/1066	46/7206	0.0107635317416
ko05416	Viral myocarditis	2/1066	55/7206	0.0128757387615
ko00562	Inositol phosphate metabolism	22/1066	89/7206	0.0149581505862
ko03022	Basal transcription factors	1/1066	44/7206	0.0165101136636
ko04630	Jak-STAT signaling pathway	10/1066	132/7206	0.0179497280429
ko00280	Valine, leucine and isoleucine degradation	2/1066	54/7206	0.0189805315541
ko05162	Measles	9/1066	120/7206	0.0194950556037
ko05161	Hepatitis B	15/1066	173/7206	0.0221773972318
ko04923	Regulation of lipolysis in adipocytes	19/1066	77/7206	0.0222537769171
ko04145	Phagosome	14/1066	162/7206	0.024710708153
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/1066	59/7206	0.0269027367464
ko04113	Meiosis - yeast	4/1066	70/7206	0.0274467598844
ko04270	Vascular smooth muscle contraction	33/1066	154/7206	0.0283448610663
ko04622	RIG-I-like receptor signaling pathway	3/1066	62/7206	0.0287712014009
ko05410	Hypertrophic cardiomyopathy (HCM)	23/1066	100/7206	0.0318409646355
ko04213	Longevity regulating pathway - multiple species	20/1066	86/7206	0.0320286042658
ko04918	Thyroid hormone synthesis	20/1066	86/7206	0.0320286042658
ko03410	Base excision repair	1/1066	38/7206	0.0356205305852
ko05230	Central carbon metabolism in cancer	19/1066	81/7206	0.0388457066146
ko04626	Plant-pathogen interaction	6/1066	18/7206	0.0392584653669
ko04722	Neurotrophin signaling pathway	33/1066	160/7206	0.0421211784955
ko04960	Aldosterone-regulated sodium reabsorption	11/1066	41/7206	0.0433415159622
ko04966	Collecting duct acid secretion	8/1066	26/7206	0.0449707158025
ko04973	Carbohydrate digestion and absorption	11/1066	42/7206	0.0476442570044
ko05140	Leishmaniasis	5/1066	75/7206	0.0485377821185