ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	91/763	145/7206	1.51937075185e-53
ko03013	RNA transport	83/763	166/7206	2.67752762947e-38
ko04110	Cell cycle	64/763	145/7206	9.73065628517e-26
ko03008	Ribosome biogenesis in eukaryotes	44/763	79/7206	3.47351939563e-23
ko05322	Systemic lupus erythematosus	58/763	151/7206	8.63708598647e-20
ko04111	Cell cycle - yeast	43/763	90/7206	2.89834896402e-19
ko03030	DNA replication	27/763	38/7206	1.18189728447e-18
ko03460	Fanconi anemia pathway	30/763	51/7206	4.2611546689e-17
ko03440	Homologous recombination	26/763	41/7206	4.00434166874e-16
ko03015	mRNA surveillance pathway	39/763	93/7206	3.45658088721e-15
ko03420	Nucleotide excision repair	25/763	46/7206	2.28695410973e-13
ko03018	RNA degradation	34/763	84/7206	7.27000819416e-13
ko00240	Pyrimidine metabolism	39/763	110/7206	2.19658313174e-12
ko04113	Meiosis - yeast	30/763	70/7206	2.85054950423e-12
ko04020	Calcium signaling pathway	1/763	265/7206	5.9391793547e-12
ko05034	Alcoholism	62/763	238/7206	7.52367617136e-12
ko03430	Mismatch repair	16/763	22/7206	8.72187706453e-12
ko04144	Endocytosis	5/763	342/7206	2.6955021151e-11
ko03020	RNA polymerase	16/763	29/7206	3.86719594509e-09
ko05010	Alzheimer's disease	1/763	202/7206	4.35979178092e-09
ko03410	Base excision repair	17/763	38/7206	7.46484762249e-08
ko05203	Viral carcinogenesis	59/763	277/7206	1.2228228319e-07
ko04921	Oxytocin signaling pathway	3/763	209/7206	2.70522696875e-07
ko03022	Basal transcription factors	17/763	44/7206	9.62405472615e-07
ko04151	PI3K-Akt signaling pathway	15/763	390/7206	1.05866526024e-06
ko04723	Retrograde endocannabinoid signaling	2/763	175/7206	1.18701380959e-06
ko04024	cAMP signaling pathway	8/763	279/7206	1.36951075072e-06
ko04724	Glutamatergic synapse	1/763	152/7206	1.43238326051e-06
ko04810	Regulation of actin cytoskeleton	8/763	264/7206	5.43830192286e-06
ko04015	Rap1 signaling pathway	9/763	278/7206	5.92698696631e-06
ko04010	MAPK signaling pathway	12/763	321/7206	6.79487859146e-06
ko04510	Focal adhesion	7/763	240/7206	9.64163733961e-06
ko04360	Axon guidance	7/763	233/7206	1.90829959282e-05
ko04062	Chemokine signaling pathway	5/763	201/7206	2.05943654726e-05
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/763	182/7206	2.38566883285e-05
ko04022	cGMP-PKG signaling pathway	6/763	216/7206	2.42393920953e-05
ko04725	Cholinergic synapse	3/763	160/7206	3.87095512637e-05
ko04270	Vascular smooth muscle contraction	3/763	154/7206	5.48083039984e-05
ko04713	Circadian entrainment	2/763	136/7206	5.70045968515e-05
ko04726	Serotonergic synapse	2/763	137/7206	5.8111236231e-05
ko04014	Ras signaling pathway	11/763	279/7206	6.11071092056e-05
ko05169	Epstein-Barr virus infection	41/763	206/7206	7.13997403262e-05
ko05414	Dilated cardiomyopathy	1/763	112/7206	7.60761670187e-05
ko04142	Lysosome	3/763	151/7206	7.95351554564e-05
ko04120	Ubiquitin mediated proteolysis	30/763	138/7206	0.000112661040856
ko04727	GABAergic synapse	1/763	110/7206	0.000116387067721
ko05032	Morphine addiction	1/763	110/7206	0.000116387067721
ko04972	Pancreatic secretion	1/763	111/7206	0.000120954853797
ko01200	Carbon metabolism	2/763	128/7206	0.000122054725123
ko04072	Phospholipase D signaling pathway	6/763	197/7206	0.000136053678505
ko05145	Toxoplasmosis	2/763	126/7206	0.000185007924869
ko04261	Adrenergic signaling in cardiomyocytes	7/763	205/7206	0.000197738878124
ko05418	Fluid shear stress and atherosclerosis	5/763	173/7206	0.000235699420206
ko04114	Oocyte meiosis	29/763	139/7206	0.000379930124983
ko04911	Insulin secretion	2/763	117/7206	0.000382263884623
ko05410	Hypertrophic cardiomyopathy (HCM)	1/763	100/7206	0.00040291326876
ko04670	Leukocyte transendothelial migration	4/763	151/7206	0.000415835538256
ko03450	Non-homologous end-joining	7/763	15/7206	0.000435163948765
ko04218	Cellular senescence	34/763	177/7206	0.000471298329062
ko05168	Herpes simplex infection	35/763	182/7206	0.000526354816204
ko04145	Phagosome	5/763	162/7206	0.000659693744707
ko04611	Platelet activation	5/763	163/7206	0.000674269213275
ko04514	Cell adhesion molecules (CAMs)	3/763	130/7206	0.000741724318627
ko04146	Peroxisome	1/763	89/7206	0.000818973678701
ko05323	Rheumatoid arthritis	1/763	89/7206	0.000818973678701
ko04920	Adipocytokine signaling pathway	1/763	89/7206	0.000818973678701
ko05166	HTLV-I infection	49/763	292/7206	0.000905878908848
ko04621	NOD-like receptor signaling pathway	5/763	157/7206	0.000910061112614
ko04530	Tight junction	10/763	228/7206	0.000948667166809
ko04924	Renin secretion	1/763	86/7206	0.00121450318875
ko05133	Pertussis	1/763	87/7206	0.00123394088561
ko04912	GnRH signaling pathway	3/763	122/7206	0.00150165642215
ko05202	Transcriptional misregulation in cancer	34/763	188/7206	0.00161639823693
ko04380	Osteoclast differentiation	4/763	134/7206	0.00163520990728
ko04620	Toll-like receptor signaling pathway	2/763	100/7206	0.00169440051442
ko04071	Sphingolipid signaling pathway	6/763	162/7206	0.00182455005389
ko04371	Apelin signaling pathway	7/763	177/7206	0.00183920309945
ko04915	Estrogen signaling pathway	4/763	131/7206	0.00230972380925
ko04650	Natural killer cell mediated cytotoxicity	2/763	97/7206	0.0024466826703
ko05132	Salmonella infection	2/763	98/7206	0.00247069853538
ko00564	Glycerophospholipid metabolism	2/763	99/7206	0.00252514211418
ko04976	Bile secretion	1/763	80/7206	0.00273922438508
ko00230	Purine metabolism	34/763	194/7206	0.00286714088615
ko04070	Phosphatidylinositol signaling system	3/763	112/7206	0.0029187455239
ko04914	Progesterone-mediated oocyte maturation	21/763	104/7206	0.00329295593508
ko04728	Dopaminergic synapse	8/763	185/7206	0.00335400601987
ko04712	Circadian rhythm - plant	4/763	7/7206	0.0033575733212
ko05140	Leishmaniasis	1/763	75/7206	0.00393205715058
ko04750	Inflammatory mediator regulation of TRP channels	4/763	122/7206	0.00448460854721
ko05205	Proteoglycans in cancer	15/763	271/7206	0.0045829524454
ko05120	Epithelial cell signaling in Helicobacter pylori infection	2/763	92/7206	0.00536338788407
ko05030	Cocaine addiction	1/763	73/7206	0.00607612197742
ko04668	TNF signaling pathway	4/763	120/7206	0.00636131860093
ko05231	Choline metabolism in cancer	5/763	134/7206	0.00647547852955
ko04933	AGE-RAGE signaling pathway in diabetic complications	5/763	135/7206	0.00658881964644
ko01230	Biosynthesis of amino acids	2/763	85/7206	0.00730131938972
ko04662	B cell receptor signaling pathway	2/763	88/7206	0.00766788516496
ko04540	Gap junction	5/763	128/7206	0.00875919391509
ko05142	Chagas disease (American trypanosomiasis)	5/763	130/7206	0.00887175857909
ko04660	T cell receptor signaling pathway	5/763	124/7206	0.0119589679559
ko00561	Glycerolipid metabolism	1/763	63/7206	0.0124464098296
ko00600	Sphingolipid metabolism	1/763	63/7206	0.0124464098296
ko04139	Mitophagy - yeast	9/763	37/7206	0.0130078721447
ko04140	Autophagy - animal	8/763	164/7206	0.0140230743227
ko05200	Pathways in cancer	36/763	492/7206	0.014864402244
ko04923	Regulation of lipolysis in adipocytes	2/763	77/7206	0.0149580608532
ko04730	Long-term depression	2/763	78/7206	0.0150109002264
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	2/763	79/7206	0.0152172155661
ko04512	ECM-receptor interaction	2/763	79/7206	0.0152172155661
ko05152	Tuberculosis	10/763	187/7206	0.0155603009027
ko00330	Arginine and proline metabolism	1/763	61/7206	0.0188675936389
ko04330	Notch signaling pathway	13/763	62/7206	0.0195368485442
ko05134	Legionellosis	2/763	74/7206	0.0213800518338
ko00562	Inositol phosphate metabolism	3/763	89/7206	0.0227557149061
ko04925	Aldosterone synthesis and secretion	4/763	105/7206	0.0234838318653
ko05321	Inflammatory bowel disease (IBD)	1/763	56/7206	0.0269060632325
ko04962	Vasopressin-regulated water reabsorption	1/763	58/7206	0.0283649119712
ko05100	Bacterial invasion of epithelial cells	4/763	99/7206	0.0311516445628
ko04214	Apoptosis - fly	2/763	72/7206	0.031343033144
ko04918	Thyroid hormone synthesis	3/763	86/7206	0.0320977445994
ko04722	Neurotrophin signaling pathway	9/763	160/7206	0.0371837777495
ko04152	AMPK signaling pathway	9/763	161/7206	0.037310661925
ko00590	Arachidonic acid metabolism	1/763	52/7206	0.0392112165886
ko04658	Th1 and Th2 cell differentiation	4/763	96/7206	0.0429071693579
ko04910	Insulin signaling pathway	10/763	172/7206	0.0435160930133
ko04210	Apoptosis	11/763	180/7206	0.049037446645