ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 63/305 145/7206 2.08033502905e-49 ko03013 RNA transport 36/305 166/7206 1.32089067457e-16 ko04110 Cell cycle 31/305 145/7206 2.9938950699e-14 ko04111 Cell cycle - yeast 23/305 90/7206 1.37113116548e-12 ko03022 Basal transcription factors 16/305 44/7206 1.02339219545e-11 ko03018 RNA degradation 19/305 84/7206 1.25151812089e-09 ko03008 Ribosome biogenesis in eukaryotes 18/305 79/7206 3.04661887401e-09 ko03030 DNA replication 12/305 38/7206 2.68261368422e-08 ko03420 Nucleotide excision repair 13/305 46/7206 3.13055937991e-08 ko00240 Pyrimidine metabolism 19/305 110/7206 1.34148302132e-07 ko04113 Meiosis - yeast 15/305 70/7206 1.55613311758e-07 ko03020 RNA polymerase 9/305 29/7206 1.83567178862e-06 ko03410 Base excision repair 10/305 38/7206 2.61900818251e-06 ko03015 mRNA surveillance pathway 15/305 93/7206 6.96440858961e-06 ko04144 Endocytosis 1/305 342/7206 1.09428544656e-05 ko04120 Ubiquitin mediated proteolysis 18/305 138/7206 1.83802108565e-05 ko03440 Homologous recombination 9/305 41/7206 4.0980363059e-05 ko04114 Oocyte meiosis 17/305 139/7206 7.22585158931e-05 ko04151 PI3K-Akt signaling pathway 3/305 390/7206 7.53352053977e-05 ko04015 Rap1 signaling pathway 1/305 278/7206 0.000107175822121 ko04014 Ras signaling pathway 1/305 279/7206 0.000107276447332 ko04024 cAMP signaling pathway 1/305 279/7206 0.000107276447332 ko05200 Pathways in cancer 6/305 492/7206 0.000165022802806 ko04010 MAPK signaling pathway 2/305 321/7206 0.000167344803717 ko03430 Mismatch repair 6/305 22/7206 0.00022978004884 ko03460 Fanconi anemia pathway 9/305 51/7206 0.000245113386528 ko04914 Progesterone-mediated oocyte maturation 13/305 104/7206 0.00041150053749 ko04510 Focal adhesion 1/305 240/7206 0.000503945571938 ko05203 Viral carcinogenesis 24/305 277/7206 0.000698823196522 ko05166 HTLV-I infection 25/305 292/7206 0.00084392964642 ko04530 Tight junction 1/305 228/7206 0.00112939996974 ko05322 Systemic lupus erythematosus 15/305 151/7206 0.00174959819774 ko05169 Epstein-Barr virus infection 18/305 206/7206 0.00393851029645 ko00230 Purine metabolism 17/305 194/7206 0.00540599037947 ko05224 Breast cancer 1/305 174/7206 0.00713007458498 ko04210 Apoptosis 1/305 180/7206 0.00732828583232 ko05012 Parkinson's disease 1/305 155/7206 0.0149611255724 ko04722 Neurotrophin signaling pathway 1/305 160/7206 0.0152126222617 ko04152 AMPK signaling pathway 1/305 161/7206 0.0153479655873 ko04145 Phagosome 1/305 162/7206 0.0155119045275 ko04611 Platelet activation 1/305 163/7206 0.0157045833868 ko04062 Chemokine signaling pathway 2/305 201/7206 0.0186269033621 ko04670 Leukocyte transendothelial migration 1/305 151/7206 0.0220497380617 ko05160 Hepatitis C 1/305 153/7206 0.0225062215078 ko04141 Protein processing in endoplasmic reticulum 2/305 184/7206 0.0249144112997 ko05152 Tuberculosis 2/305 187/7206 0.0251981685139 ko04390 Hippo signaling pathway 2/305 188/7206 0.0253628063213 ko04623 Cytosolic DNA-sensing pathway 5/305 41/7206 0.0282794772687 ko04916 Melanogenesis 1/305 142/7206 0.0318987078325 ko04910 Insulin signaling pathway 2/305 172/7206 0.0349153927223 ko04115 p53 signaling pathway 7/305 74/7206 0.0362938260279 ko04310 Wnt signaling pathway 2/305 181/7206 0.0363770373988 ko01200 Carbon metabolism 1/305 128/7206 0.0447649599946 ko04540 Gap junction 1/305 128/7206 0.0447649599946 ko04630 Jak-STAT signaling pathway 1/305 132/7206 0.0456464964611