ko pathway ratio_in_study ratio_in_pop p_value ko05150 Staphylococcus aureus infection 13/272 36/7206 2.52265141391e-10 ko04060 Cytokine-cytokine receptor interaction 28/272 191/7206 4.48219492867e-10 ko04380 Osteoclast differentiation 23/272 134/7206 7.47804929655e-10 ko04610 Complement and coagulation cascades 16/272 79/7206 2.77378197166e-08 ko04621 NOD-like receptor signaling pathway 22/272 157/7206 8.36062964988e-08 ko05164 Influenza A 22/272 167/7206 2.54764691979e-07 ko04630 Jak-STAT signaling pathway 19/272 132/7206 4.30510223683e-07 ko05140 Leishmaniasis 14/272 75/7206 6.04721076941e-07 ko04611 Platelet activation 21/272 163/7206 7.03190463176e-07 ko04640 Hematopoietic cell lineage 12/272 64/7206 3.7292853526e-06 ko05133 Pertussis 14/272 87/7206 3.88207759091e-06 ko04620 Toll-like receptor signaling pathway 15/272 100/7206 4.32125234836e-06 ko05162 Measles 16/272 120/7206 9.88501300285e-06 ko05168 Herpes simplex infection 20/272 182/7206 1.53320020598e-05 ko04662 B cell receptor signaling pathway 13/272 88/7206 2.25019743914e-05 ko05321 Inflammatory bowel disease (IBD) 10/272 56/7206 3.80772361706e-05 ko04660 T cell receptor signaling pathway 15/272 124/7206 6.02338242735e-05 ko04650 Natural killer cell mediated cytotoxicity 13/272 97/7206 6.44569427244e-05 ko00120 Primary bile acid biosynthesis 6/272 20/7206 6.78451964545e-05 ko05145 Toxoplasmosis 15/272 126/7206 7.26012711387e-05 ko05152 Tuberculosis 19/272 187/7206 7.47055799682e-05 ko04622 RIG-I-like receptor signaling pathway 10/272 62/7206 9.41376318777e-05 ko04658 Th1 and Th2 cell differentiation 12/272 96/7206 0.000241557892334 ko04064 NF-kappa B signaling pathway 12/272 96/7206 0.000241557892334 ko05310 Asthma 5/272 17/7206 0.000314518308799 ko04672 Intestinal immune network for IgA production 7/272 37/7206 0.000393033432245 ko04659 Th17 cell differentiation 12/272 106/7206 0.000608543642957 ko04623 Cytosolic DNA-sensing pathway 7/272 41/7206 0.000754361248393 ko05340 Primary immunodeficiency 6/272 30/7206 0.000756116414318 ko05161 Hepatitis B 16/272 173/7206 0.000792265098763 ko05131 Shigellosis 10/272 82/7206 0.000963926692062 ko05144 Malaria 7/272 45/7206 0.00133872267489 ko05034 Alcoholism 1/272 238/7206 0.00159226463596 ko05323 Rheumatoid arthritis 10/272 89/7206 0.00181757054887 ko04668 TNF signaling pathway 12/272 120/7206 0.00182496905196 ko05160 Hepatitis C 14/272 153/7206 0.00184551329176 ko04062 Chemokine signaling pathway 17/272 201/7206 0.00188189559241 ko04666 Fc gamma R-mediated phagocytosis 12/272 122/7206 0.00210171439671 ko04664 Fc epsilon RI signaling pathway 9/272 77/7206 0.00231718778244 ko05167 Kaposi's sarcoma-associated herpesvirus infection 16/272 191/7206 0.00283182476497 ko05134 Legionellosis 8/272 74/7206 0.00646913792873 ko00643 Styrene degradation 2/272 4/7206 0.00809873717832 ko04512 ECM-receptor interaction 8/272 79/7206 0.0095308207587 ko05132 Salmonella infection 9/272 98/7206 0.0113917504393 ko05330 Allograft rejection 4/272 24/7206 0.0116196325566 ko00281 Geraniol degradation 2/272 5/7206 0.0131627325364 ko04670 Leukocyte transendothelial migration 12/272 151/7206 0.0143732106087 ko00140 Steroid hormone biosynthesis 5/272 41/7206 0.0182176459755 ko04920 Adipocytokine signaling pathway 8/272 89/7206 0.0187146326443 ko00830 Retinol metabolism 5/272 42/7206 0.0200614609563 ko04145 Phagosome 12/272 162/7206 0.0210955460879 ko05320 Autoimmune thyroid disease 4/272 29/7206 0.0224247567591 ko04217 Necroptosis 13/272 178/7206 0.0248452670495 ko04612 Antigen processing and presentation 7/272 77/7206 0.0256120367015 ko05332 Graft-versus-host disease 3/272 18/7206 0.0285152347612 ko05142 Chagas disease (American trypanosomiasis) 10/272 130/7206 0.0312290283766 ko00592 alpha-Linolenic acid metabolism 3/272 19/7206 0.0329404775843 ko04110 Cell cycle 1/272 145/7206 0.0451948636521 ko00590 Arachidonic acid metabolism 5/272 52/7206 0.0453355874587 ko04917 Prolactin signaling pathway 7/272 87/7206 0.0454716090727 ko04210 Apoptosis 12/272 180/7206 0.046775408218 ko04020 Calcium signaling pathway 4/272 265/7206 0.0475005661825 ko04724 Glutamatergic synapse 1/272 152/7206 0.0476711805551 ko04141 Protein processing in endoplasmic reticulum 2/272 184/7206 0.0489771506887 ko04390 Hippo signaling pathway 2/272 188/7206 0.0495635986256