ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	159/746	423/7206	2.41007645931e-54
ko05033	Nicotine addiction	47/746	56/7206	4.13122368287e-38
ko04724	Glutamatergic synapse	71/746	152/7206	4.86068910693e-31
ko04727	GABAergic synapse	54/746	110/7206	3.94672770616e-25
ko05032	Morphine addiction	51/746	110/7206	2.40011332899e-22
ko04713	Circadian entrainment	57/746	136/7206	3.76705641677e-22
ko04723	Retrograde endocannabinoid signaling	63/746	175/7206	3.27325954745e-20
ko04728	Dopaminergic synapse	65/746	185/7206	3.58017267493e-20
ko04024	cAMP signaling pathway	79/746	279/7206	8.21443838855e-18
ko04721	Synaptic vesicle cycle	35/746	80/7206	9.77824272678e-15
ko04911	Insulin secretion	43/746	117/7206	1.63639894228e-14
ko04725	Cholinergic synapse	51/746	160/7206	4.40629131533e-14
ko05031	Amphetamine addiction	34/746	91/7206	5.67153081867e-12
ko04921	Oxytocin signaling pathway	56/746	209/7206	7.82188927601e-12
ko04020	Calcium signaling pathway	65/746	265/7206	1.64336098289e-11
ko04726	Serotonergic synapse	42/746	137/7206	3.42029683972e-11
ko05030	Cocaine addiction	29/746	73/7206	3.62862106525e-11
ko04261	Adrenergic signaling in cardiomyocytes	54/746	205/7206	3.85141190945e-11
ko04742	Taste transduction	26/746	61/7206	5.78306378998e-11
ko04720	Long-term potentiation	34/746	99/7206	8.53390853518e-11
ko05014	Amyotrophic lateral sclerosis (ALS)	26/746	74/7206	8.39773850318e-09
ko04010	MAPK signaling pathway	66/746	321/7206	2.9378524817e-08
ko04970	Salivary secretion	28/746	95/7206	1.72034569837e-07
ko04971	Gastric acid secretion	28/746	98/7206	3.52698307836e-07
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/746	79/7206	7.09599053261e-07
ko04925	Aldosterone synthesis and secretion	28/746	105/7206	1.642827941e-06
ko04972	Pancreatic secretion	29/746	111/7206	1.69481761757e-06
ko04514	Cell adhesion molecules (CAMs)	32/746	130/7206	2.64416067637e-06
ko04060	Cytokine-cytokine receptor interaction	3/746	191/7206	2.82272569954e-06
ko03040	Spliceosome	1/746	145/7206	3.13040644912e-06
ko04360	Axon guidance	47/746	233/7206	5.30482639028e-06
ko05203	Viral carcinogenesis	9/746	277/7206	1.1799816982e-05
ko04260	Cardiac muscle contraction	25/746	98/7206	1.37961074193e-05
ko04072	Phospholipase D signaling pathway	40/746	197/7206	2.41457498306e-05
ko05164	Influenza A	3/746	167/7206	2.68515358894e-05
ko05168	Herpes simplex infection	4/746	182/7206	3.48556978595e-05
ko05414	Dilated cardiomyopathy	26/746	112/7206	5.94602877607e-05
ko04730	Long-term depression	20/746	78/7206	9.15045021386e-05
ko04540	Gap junction	27/746	128/7206	0.00031950083297
ko04120	Ubiquitin mediated proteolysis	3/746	138/7206	0.00034806424812
ko04915	Estrogen signaling pathway	27/746	131/7206	0.000404872543637
ko04022	cGMP-PKG signaling pathway	39/746	216/7206	0.000571667312554
ko05322	Systemic lupus erythematosus	4/746	151/7206	0.000603342425432
ko03013	RNA transport	5/746	166/7206	0.000672343669824
ko05169	Epstein-Barr virus infection	8/746	206/7206	0.00101925519106
ko04621	NOD-like receptor signaling pathway	5/746	157/7206	0.0012899108958
ko04350	TGF-beta signaling pathway	2/746	103/7206	0.00171155476689
ko03018	RNA degradation	1/746	84/7206	0.00181721838915
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/746	182/7206	0.00186818238128
ko04964	Proximal tubule bicarbonate reclamation	9/746	29/7206	0.00193081088695
ko05162	Measles	3/746	120/7206	0.00212043736965
ko04750	Inflammatory mediator regulation of TRP channels	24/746	122/7206	0.00225393359759
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/746	59/7206	0.00226747430519
ko04015	Rap1 signaling pathway	45/746	278/7206	0.00240476796375
ko03008	Ribosome biogenesis in eukaryotes	1/746	79/7206	0.00268364652647
ko04612	Antigen processing and presentation	1/746	77/7206	0.00399341402494
ko05410	Hypertrophic cardiomyopathy (HCM)	20/746	100/7206	0.00410517553128
ko00240	Pyrimidine metabolism	3/746	110/7206	0.00416951072249
ko04976	Bile secretion	17/746	80/7206	0.00446582078727
ko04740	Olfactory transduction	17/746	80/7206	0.00446582078727
ko04150	mTOR signaling pathway	8/746	184/7206	0.00449487062055
ko04141	Protein processing in endoplasmic reticulum	8/746	184/7206	0.00449487062055
ko04014	Ras signaling pathway	44/746	279/7206	0.0047212652522
ko05205	Proteoglycans in cancer	15/746	271/7206	0.0058822479265
ko04070	Phosphatidylinositol signaling system	21/746	112/7206	0.00694999200522
ko04110	Cell cycle	6/746	145/7206	0.00869712245061
ko04930	Type II diabetes mellitus	12/746	54/7206	0.0106353272925
ko05034	Alcoholism	37/746	238/7206	0.0122451633824
ko04745	Phototransduction - fly	9/746	38/7206	0.0134881893087
ko05231	Choline metabolism in cancer	23/746	134/7206	0.0140844057861
ko04064	NF-kappa B signaling pathway	3/746	96/7206	0.0166634610517
ko04510	Focal adhesion	14/746	240/7206	0.0173469857445
ko00330	Arginine and proline metabolism	1/746	61/7206	0.0184756466323
ko04330	Notch signaling pathway	1/746	62/7206	0.0188193373406
ko04924	Renin secretion	16/746	86/7206	0.0188556742043
ko05140	Leishmaniasis	2/746	75/7206	0.0214700118759
ko05161	Hepatitis B	9/746	173/7206	0.0223060055647
ko04146	Peroxisome	3/746	89/7206	0.0227468176133
ko05321	Inflammatory bowel disease (IBD)	1/746	56/7206	0.0268345770511
ko04630	Jak-STAT signaling pathway	6/746	132/7206	0.0289682105942
ko04214	Apoptosis - fly	2/746	72/7206	0.0306652895621
ko00310	Lysine degradation	2/746	73/7206	0.0311166692136
ko04722	Neurotrophin signaling pathway	25/746	160/7206	0.0347111946196
ko04912	GnRH signaling pathway	20/746	122/7206	0.034801242955
ko04973	Carbohydrate digestion and absorption	9/746	42/7206	0.0354422869722
ko04923	Regulation of lipolysis in adipocytes	14/746	77/7206	0.0356229910301
ko04140	Autophagy - animal	9/746	164/7206	0.0374121147785
ko05145	Toxoplasmosis	6/746	126/7206	0.0376820565545
ko00515	Mannose type O-glycan biosynthesis	6/746	25/7206	0.0384435931718
ko01200	Carbon metabolism	6/746	128/7206	0.038558579012
ko05016	Huntington's disease	13/746	215/7206	0.0397170351507
ko05215	Prostate cancer	5/746	111/7206	0.0402636902935
ko00480	Glutathione metabolism	1/746	55/7206	0.0410742087469
ko04940	Type I diabetes mellitus	7/746	32/7206	0.0417884636297
ko04138	Autophagy - yeast	3/746	81/7206	0.0436948921895
ko04966	Collecting duct acid secretion	6/746	26/7206	0.0457624388574
ko04962	Vasopressin-regulated water reabsorption	11/746	58/7206	0.046827804714
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/746	14/7206	0.0490471176838