ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 27/146 191/7206 5.52102395679e-16 ko05140 Leishmaniasis 16/146 75/7206 1.08334689993e-12 ko05321 Inflammatory bowel disease (IBD) 14/146 56/7206 2.93464423672e-12 ko04380 Osteoclast differentiation 19/146 134/7206 1.59845515348e-11 ko05152 Tuberculosis 22/146 187/7206 1.60502229197e-11 ko05145 Toxoplasmosis 17/146 126/7206 4.49600049323e-10 ko04650 Natural killer cell mediated cytotoxicity 15/146 97/7206 7.20572007097e-10 ko05150 Staphylococcus aureus infection 10/146 36/7206 1.38661668648e-09 ko04064 NF-kappa B signaling pathway 14/146 96/7206 6.04897747138e-09 ko05330 Allograft rejection 8/146 24/7206 1.31043774118e-08 ko05144 Malaria 10/146 45/7206 1.48912588189e-08 ko04217 Necroptosis 18/146 178/7206 1.5129561525e-08 ko04659 Th17 cell differentiation 14/146 106/7206 2.24664334119e-08 ko04630 Jak-STAT signaling pathway 15/146 132/7206 5.4706561428e-08 ko04660 T cell receptor signaling pathway 14/146 124/7206 1.69160612993e-07 ko05164 Influenza A 16/146 167/7206 2.1530446924e-07 ko05310 Asthma 6/146 17/7206 6.42761288282e-07 ko05162 Measles 13/146 120/7206 7.73763897097e-07 ko05340 Primary immunodeficiency 7/146 30/7206 1.67221568892e-06 ko04658 Th1 and Th2 cell differentiation 11/146 96/7206 3.26567111791e-06 ko05168 Herpes simplex infection 15/146 182/7206 3.58998178349e-06 ko04620 Toll-like receptor signaling pathway 11/146 100/7206 4.89331440361e-06 ko05133 Pertussis 10/146 87/7206 9.03021803754e-06 ko04662 B cell receptor signaling pathway 10/146 88/7206 1.00133839006e-05 ko04621 NOD-like receptor signaling pathway 13/146 157/7206 1.5765335463e-05 ko05320 Autoimmune thyroid disease 6/146 29/7206 2.01810686091e-05 ko05332 Graft-versus-host disease 5/146 18/7206 2.20819943138e-05 ko04664 Fc epsilon RI signaling pathway 9/146 77/7206 2.24552003864e-05 ko04666 Fc gamma R-mediated phagocytosis 11/146 122/7206 3.31164536061e-05 ko05142 Chagas disease (American trypanosomiasis) 11/146 130/7206 5.97118472211e-05 ko04672 Intestinal immune network for IgA production 6/146 37/7206 8.64191146048e-05 ko04145 Phagosome 12/146 162/7206 0.000100950215602 ko05167 Kaposi's sarcoma-associated herpesvirus infection 13/146 191/7206 0.000122542969513 ko05161 Hepatitis B 12/146 173/7206 0.000188546826038 ko04062 Chemokine signaling pathway 13/146 201/7206 0.000204261921171 ko04940 Type I diabetes mellitus 5/146 32/7206 0.000412925881599 ko05143 African trypanosomiasis 5/146 32/7206 0.000412925881599 ko05323 Rheumatoid arthritis 8/146 89/7206 0.000414228845386 ko04612 Antigen processing and presentation 7/146 77/7206 0.000892596275334 ko05169 Epstein-Barr virus infection 12/146 206/7206 0.000921680314194 ko04670 Leukocyte transendothelial migration 10/146 151/7206 0.000937629004065 ko04640 Hematopoietic cell lineage 6/146 64/7206 0.00177973642243 ko05132 Salmonella infection 7/146 98/7206 0.00361023820657 ko05146 Amoebiasis 7/146 99/7206 0.00382047548711 ko04514 Cell adhesion molecules (CAMs) 8/146 130/7206 0.00475336288212 ko05416 Viral myocarditis 5/146 55/7206 0.00491385831164 ko04610 Complement and coagulation cascades 6/146 79/7206 0.00515145525255 ko04611 Platelet activation 9/146 163/7206 0.00571108253537 ko04622 RIG-I-like receptor signaling pathway 5/146 62/7206 0.00816656845632 ko04144 Endocytosis 14/146 342/7206 0.0100102041556 ko05322 Systemic lupus erythematosus 8/146 151/7206 0.0114043923611 ko05160 Hepatitis C 8/146 153/7206 0.012282220171 ko05131 Shigellosis 5/146 82/7206 0.0250106521992 ko04917 Prolactin signaling pathway 5/146 87/7206 0.0312835290572 ko04668 TNF signaling pathway 6/146 120/7206 0.0346510524106 ko00660 C5-Branched dibasic acid metabolism 1/146 2/7206 0.0401140386719 ko04623 Cytosolic DNA-sensing pathway 3/146 41/7206 0.0496272941476