ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 28/296 191/7206 3.12492842728e-09 ko05164 Influenza A 25/296 167/7206 1.47997385162e-08 ko05145 Toxoplasmosis 20/296 126/7206 1.6195811265e-07 ko05152 Tuberculosis 24/296 187/7206 5.67090498938e-07 ko00120 Primary bile acid biosynthesis 8/296 20/7206 6.03866660213e-07 ko04650 Natural killer cell mediated cytotoxicity 16/296 97/7206 1.70710973213e-06 ko05340 Primary immunodeficiency 9/296 30/7206 1.96937025247e-06 ko04380 Osteoclast differentiation 19/296 134/7206 1.9738054347e-06 ko05321 Inflammatory bowel disease (IBD) 12/296 56/7206 2.03418424293e-06 ko04621 NOD-like receptor signaling pathway 20/296 157/7206 5.74893397124e-06 ko05140 Leishmaniasis 13/296 75/7206 9.29757344196e-06 ko04217 Necroptosis 21/296 178/7206 1.13407466282e-05 ko04672 Intestinal immune network for IgA production 9/296 37/7206 1.32815634468e-05 ko05162 Measles 16/296 120/7206 2.8382838609e-05 ko00590 Arachidonic acid metabolism 10/296 52/7206 4.00743098701e-05 ko05160 Hepatitis C 18/296 153/7206 5.03485000733e-05 ko04610 Complement and coagulation cascades 12/296 79/7206 7.99409039921e-05 ko04658 Th1 and Th2 cell differentiation 13/296 96/7206 0.00013649120163 ko05168 Herpes simplex infection 19/296 182/7206 0.000159409633751 ko04612 Antigen processing and presentation 11/296 77/7206 0.000276653387779 ko05167 Kaposi's sarcoma-associated herpesvirus infection 19/296 191/7206 0.00029900035519 ko05330 Allograft rejection 6/296 24/7206 0.000328303894038 ko04611 Platelet activation 17/296 163/7206 0.000356217290064 ko04668 TNF signaling pathway 14/296 120/7206 0.000376923650748 ko04670 Leukocyte transendothelial migration 16/296 151/7206 0.000443022274626 ko05310 Asthma 5/296 17/7206 0.000465338366451 ko04064 NF-kappa B signaling pathway 12/296 96/7206 0.000522507313444 ko04660 T cell receptor signaling pathway 14/296 124/7206 0.000528432232699 ko05150 Staphylococcus aureus infection 7/296 36/7206 0.000549256997914 ko04620 Toll-like receptor signaling pathway 12/296 100/7206 0.000758920234634 ko00592 alpha-Linolenic acid metabolism 5/296 19/7206 0.000817180169759 ko04145 Phagosome 16/296 162/7206 0.000961847092253 ko05320 Autoimmune thyroid disease 6/296 29/7206 0.000974351002546 ko04630 Jak-STAT signaling pathway 14/296 132/7206 0.000990433143494 ko04664 Fc epsilon RI signaling pathway 10/296 77/7206 0.00112098559132 ko04659 Th17 cell differentiation 12/296 106/7206 0.00127676495384 ko05161 Hepatitis B 16/296 173/7206 0.00257088762986 ko05323 Rheumatoid arthritis 10/296 89/7206 0.00336985081547 ko05332 Graft-versus-host disease 4/296 18/7206 0.00540642014277 ko04070 Phosphatidylinositol signaling system 11/296 112/7206 0.00609169384412 ko05416 Viral myocarditis 7/296 55/7206 0.00686452174991 ko04390 Hippo signaling pathway 1/296 188/7206 0.00757690989027 ko05133 Pertussis 9/296 87/7206 0.00908887337588 ko04072 Phospholipase D signaling pathway 16/296 197/7206 0.00916554296762 ko05144 Malaria 6/296 45/7206 0.00964153994987 ko04662 B cell receptor signaling pathway 9/296 88/7206 0.00977104655998 ko05231 Choline metabolism in cancer 12/296 134/7206 0.0122531611226 ko01524 Platinum drug resistance 8/296 76/7206 0.0123022631728 ko04622 RIG-I-like receptor signaling pathway 7/296 62/7206 0.0130478494812 ko04640 Hematopoietic cell lineage 7/296 64/7206 0.015379743819 ko00982 Drug metabolism - cytochrome P450 5/296 37/7206 0.0167620924778 ko04666 Fc gamma R-mediated phagocytosis 11/296 122/7206 0.0170897208181 ko05230 Central carbon metabolism in cancer 8/296 81/7206 0.0176131493217 ko05146 Amoebiasis 9/296 99/7206 0.020054137814 ko04514 Cell adhesion molecules (CAMs) 11/296 130/7206 0.0217167963775 ko03320 PPAR signaling pathway 7/296 69/7206 0.0224785728257 ko00140 Steroid hormone biosynthesis 5/296 41/7206 0.0252457993067 ko04623 Cytosolic DNA-sensing pathway 5/296 41/7206 0.0252457993067 ko04917 Prolactin signaling pathway 8/296 87/7206 0.0259513417693 ko04933 AGE-RAGE signaling pathway in diabetic complications 11/296 135/7206 0.0259997736687 ko04062 Chemokine signaling pathway 15/296 201/7206 0.0275661416083 ko00051 Fructose and mannose metabolism 5/296 42/7206 0.027727676089 ko00565 Ether lipid metabolism 5/296 42/7206 0.027727676089 ko03040 Spliceosome 1/296 145/7206 0.031630413463 ko04142 Lysosome 12/296 151/7206 0.0338312433802 ko04725 Cholinergic synapse 12/296 160/7206 0.0405725637318 ko04940 Type I diabetes mellitus 4/296 32/7206 0.0405834698207 ko05215 Prostate cancer 9/296 111/7206 0.0475447652669