ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	173/936	423/7206	2.70314540464e-50
ko05033	Nicotine addiction	46/936	56/7206	6.12403920136e-32
ko04724	Glutamatergic synapse	76/936	152/7206	6.44528396885e-29
ko05032	Morphine addiction	57/936	110/7206	6.38341606029e-23
ko04727	GABAergic synapse	56/936	110/7206	4.78699660383e-22
ko04713	Circadian entrainment	60/936	136/7206	1.56002284141e-19
ko04728	Dopaminergic synapse	72/936	185/7206	2.04725894323e-19
ko04725	Cholinergic synapse	65/936	160/7206	9.04765568272e-19
ko04723	Retrograde endocannabinoid signaling	68/936	175/7206	2.39099963857e-18
ko04721	Synaptic vesicle cycle	42/936	80/7206	1.81128404585e-17
ko04024	cAMP signaling pathway	88/936	279/7206	1.35772340818e-16
ko04911	Insulin secretion	48/936	117/7206	2.32555513189e-14
ko04742	Taste transduction	31/936	61/7206	1.00030086731e-12
ko04921	Oxytocin signaling pathway	66/936	209/7206	1.11595460482e-12
ko04020	Calcium signaling pathway	76/936	265/7206	4.80832458409e-12
ko04726	Serotonergic synapse	49/936	137/7206	5.805068033e-12
ko05031	Amphetamine addiction	37/936	91/7206	3.17957841791e-11
ko04261	Adrenergic signaling in cardiomyocytes	61/936	205/7206	1.26012700962e-10
ko04720	Long-term potentiation	38/936	99/7206	1.32378862027e-10
ko04970	Salivary secretion	35/936	95/7206	2.60343635932e-09
ko04744	Phototransduction	19/936	36/7206	1.17714044058e-08
ko05203	Viral carcinogenesis	9/936	277/7206	2.53913918812e-08
ko05030	Cocaine addiction	28/936	73/7206	3.7322167745e-08
ko03040	Spliceosome	1/936	145/7206	5.75471806877e-08
ko04010	MAPK signaling pathway	75/936	321/7206	2.35875514759e-07
ko04971	Gastric acid secretion	32/936	98/7206	3.28969861233e-07
ko04060	Cytokine-cytokine receptor interaction	5/936	191/7206	9.25132305996e-07
ko05168	Herpes simplex infection	5/936	182/7206	1.84698086642e-06
ko04925	Aldosterone synthesis and secretion	32/936	105/7206	2.25389163806e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/936	74/7206	3.17350061076e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/936	79/7206	3.52833482241e-06
ko04740	Olfactory transduction	26/936	80/7206	4.59325776678e-06
ko04360	Axon guidance	55/936	233/7206	6.28076110874e-06
ko05164	Influenza A	5/936	167/7206	1.15981794738e-05
ko04514	Cell adhesion molecules (CAMs)	35/936	130/7206	1.63366233411e-05
ko04072	Phospholipase D signaling pathway	47/936	197/7206	2.19849913238e-05
ko04972	Pancreatic secretion	31/936	111/7206	2.24546310727e-05
ko04022	cGMP-PKG signaling pathway	50/936	216/7206	3.14014195968e-05
ko04730	Long-term depression	24/936	78/7206	4.80045718188e-05
ko05169	Epstein-Barr virus infection	9/936	206/7206	5.10833518491e-05
ko03013	RNA transport	6/936	166/7206	5.60758298738e-05
ko04120	Ubiquitin mediated proteolysis	4/936	138/7206	5.81292545729e-05
ko05322	Systemic lupus erythematosus	5/936	151/7206	6.98632499259e-05
ko04961	Endocrine and other factor-regulated calcium reabsorption	19/936	59/7206	0.000100495625894
ko04260	Cardiac muscle contraction	27/936	98/7206	0.000102289432463
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/936	182/7206	0.000127368523633
ko04745	Phototransduction - fly	14/936	38/7206	0.000165705701885
ko04540	Gap junction	32/936	128/7206	0.000172697087787
ko04014	Ras signaling pathway	58/936	279/7206	0.000248518674565
ko04924	Renin secretion	24/936	86/7206	0.000249891416423
ko04621	NOD-like receptor signaling pathway	7/936	157/7206	0.000453758096395
ko04612	Antigen processing and presentation	1/936	77/7206	0.000478167083041
ko04110	Cell cycle	6/936	145/7206	0.000628635283305
ko04750	Inflammatory mediator regulation of TRP channels	29/936	122/7206	0.000957217074657
ko04966	Collecting duct acid secretion	10/936	26/7206	0.000967781113509
ko04214	Apoptosis - fly	1/936	72/7206	0.00111332931244
ko04141	Protein processing in endoplasmic reticulum	10/936	184/7206	0.00114396421098
ko04915	Estrogen signaling pathway	30/936	131/7206	0.00148554724583
ko04070	Phosphatidylinositol signaling system	27/936	112/7206	0.00152395152393
ko05414	Dilated cardiomyopathy	27/936	112/7206	0.00152395152393
ko05166	HTLV-I infection	21/936	292/7206	0.00178029230748
ko03008	Ribosome biogenesis in eukaryotes	2/936	79/7206	0.0021661152698
ko05205	Proteoglycans in cancer	19/936	271/7206	0.00222512205317
ko05162	Measles	5/936	120/7206	0.00224461802439
ko04640	Hematopoietic cell lineage	1/936	64/7206	0.00234884323057
ko04964	Proximal tubule bicarbonate reclamation	10/936	29/7206	0.00253243572295
ko04350	TGF-beta signaling pathway	4/936	103/7206	0.0028709644244
ko04976	Bile secretion	20/936	80/7206	0.00367793833085
ko05140	Leishmaniasis	2/936	75/7206	0.00480222304078
ko03018	RNA degradation	3/936	84/7206	0.00527585592081
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/936	14/7206	0.0056135223546
ko04064	NF-kappa B signaling pathway	4/936	96/7206	0.00565235148745
ko05161	Hepatitis B	11/936	173/7206	0.00589697505196
ko00240	Pyrimidine metabolism	5/936	110/7206	0.00595573730965
ko04140	Autophagy - animal	10/936	164/7206	0.00644877188302
ko00480	Glutathione metabolism	1/936	55/7206	0.00773051358669
ko05410	Hypertrophic cardiomyopathy (HCM)	22/936	100/7206	0.0104936258247
ko04630	Jak-STAT signaling pathway	8/936	132/7206	0.0128709168801
ko04015	Rap1 signaling pathway	50/936	278/7206	0.0139626111898
ko05215	Prostate cancer	6/936	111/7206	0.0146536029911
ko04657	IL-17 signaling pathway	4/936	87/7206	0.0152762992107
ko04146	Peroxisome	4/936	89/7206	0.0158622028876
ko05219	Bladder cancer	1/936	48/7206	0.0168052402454
ko00380	Tryptophan metabolism	1/936	50/7206	0.0175586446668
ko04973	Carbohydrate digestion and absorption	11/936	42/7206	0.0185953334222
ko04142	Lysosome	10/936	151/7206	0.0192122623381
ko04912	GnRH signaling pathway	25/936	122/7206	0.0198506843571
ko00330	Arginine and proline metabolism	2/936	61/7206	0.0199782489212
ko04330	Notch signaling pathway	2/936	62/7206	0.0205099532064
ko05110	Vibrio cholerae infection	15/936	63/7206	0.0213523228474
ko04626	Plant-pathogen interaction	6/936	18/7206	0.0219862822952
ko01200	Carbon metabolism	8/936	128/7206	0.0229914877938
ko04217	Necroptosis	13/936	178/7206	0.0231732069287
ko04930	Type II diabetes mellitus	13/936	54/7206	0.0232934748723
ko00071	Fatty acid degradation	1/936	45/7206	0.0248050743996
ko03420	Nucleotide excision repair	1/936	46/7206	0.0251846310509
ko05321	Inflammatory bowel disease (IBD)	2/936	56/7206	0.0283117389688
ko03320	PPAR signaling pathway	3/936	69/7206	0.0294466075612
ko04978	Mineral absorption	10/936	40/7206	0.0322706150082
ko00983	Drug metabolism - other enzymes	1/936	42/7206	0.036559462082
ko00140	Steroid hormone biosynthesis	1/936	41/7206	0.0365614977666
ko05231	Choline metabolism in cancer	26/936	134/7206	0.0366115209762
ko03022	Basal transcription factors	1/936	44/7206	0.0385445680843
ko04668	TNF signaling pathway	8/936	120/7206	0.0389308543075
ko01524	Platinum drug resistance	4/936	76/7206	0.039723914903
ko04071	Sphingolipid signaling pathway	30/936	162/7206	0.0434778003892
ko04658	Th1 and Th2 cell differentiation	6/936	96/7206	0.0466392703227