ko pathway ratio_in_study ratio_in_pop p_value ko04668 TNF signaling pathway 8/84 120/7206 7.09420355291e-05 ko01522 Endocrine resistance 7/84 124/7206 0.000569947562889 ko05146 Amoebiasis 6/84 99/7206 0.000989164488499 ko05160 Hepatitis C 7/84 153/7206 0.00195642500421 ko04072 Phospholipase D signaling pathway 8/84 197/7206 0.00199283307619 ko04730 Long-term depression 5/84 78/7206 0.00206966396849 ko04071 Sphingolipid signaling pathway 7/84 162/7206 0.00270504174151 ko04915 Estrogen signaling pathway 6/84 131/7206 0.00410637313069 ko04217 Necroptosis 7/84 178/7206 0.00455989512254 ko04931 Insulin resistance 6/84 137/7206 0.00510985776642 ko05100 Bacterial invasion of epithelial cells 5/84 99/7206 0.00579795000188 ko04060 Cytokine-cytokine receptor interaction 7/84 191/7206 0.00667241796995 ko05200 Pathways in cancer 13/84 492/7206 0.00679776447847 ko01521 EGFR tyrosine kinase inhibitor resistance 5/84 106/7206 0.00771209944003 ko05215 Prostate cancer 5/84 111/7206 0.00932356771607 ko04810 Regulation of actin cytoskeleton 8/84 264/7206 0.0114734231634 ko04611 Platelet activation 6/84 163/7206 0.0116224498928 ko00565 Ether lipid metabolism 3/84 42/7206 0.0126488173373 ko04068 FoxO signaling pathway 6/84 167/7206 0.0129877653866 ko04610 Complement and coagulation cascades 4/84 79/7206 0.0133152397985 ko05214 Glioma 4/84 79/7206 0.0133152397985 ko04912 GnRH signaling pathway 5/84 122/7206 0.01365845913 ko04750 Inflammatory mediator regulation of TRP channels 5/84 122/7206 0.01365845913 ko04211 Longevity regulating pathway 5/84 123/7206 0.0141098486461 ko05161 Hepatitis B 6/84 173/7206 0.0152419675341 ko04014 Ras signaling pathway 8/84 279/7206 0.0156059166086 ko05224 Breast cancer 6/84 174/7206 0.015642552282 ko05212 Pancreatic cancer 4/84 83/7206 0.0157265686552 ko05220 Chronic myeloid leukemia 4/84 85/7206 0.017028915413 ko05210 Colorectal cancer 4/84 86/7206 0.0177046950582 ko04918 Thyroid hormone synthesis 4/84 86/7206 0.0177046950582 ko04380 Osteoclast differentiation 5/84 134/7206 0.0197525212914 ko00592 alpha-Linolenic acid metabolism 2/84 19/7206 0.0201918281275 ko04933 AGE-RAGE signaling pathway in diabetic complications 5/84 135/7206 0.0203292622282 ko00590 Arachidonic acid metabolism 3/84 52/7206 0.0224128376677 ko04064 NF-kappa B signaling pathway 4/84 96/7206 0.0253898896106 ko00591 Linoleic acid metabolism 2/84 22/7206 0.0266699808793 ko00564 Glycerophospholipid metabolism 4/84 99/7206 0.028032255652 ko04962 Vasopressin-regulated water reabsorption 3/84 58/7206 0.0297806679635 ko04270 Vascular smooth muscle contraction 5/84 154/7206 0.0334470926958 ko00261 Monobactam biosynthesis 1/84 3/7206 0.0345695296182 ko05213 Endometrial cancer 3/84 62/7206 0.035319589144 ko04621 NOD-like receptor signaling pathway 5/84 157/7206 0.0359079185632 ko05221 Acute myeloid leukemia 3/84 63/7206 0.0367819467145 ko04012 ErbB signaling pathway 4/84 109/7206 0.0379937208016 ko05223 Non-small cell lung cancer 3/84 66/7206 0.0413533932767 ko04015 Rap1 signaling pathway 7/84 278/7206 0.0427535790821 ko00512 Mucin type O-glycan biosynthesis 2/84 29/7206 0.0444883517654 ko04151 PI3K-Akt signaling pathway 9/84 390/7206 0.0460572806526 ko04910 Insulin signaling pathway 5/84 172/7206 0.0498734524983