ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	135/856	423/7206	6.78191429986e-30
ko04724	Glutamatergic synapse	67/856	152/7206	6.62533325981e-24
ko05033	Nicotine addiction	38/856	56/7206	8.45665205074e-23
ko04721	Synaptic vesicle cycle	43/856	80/7206	7.03652635239e-20
ko04713	Circadian entrainment	56/856	136/7206	1.89145477745e-18
ko05032	Morphine addiction	48/856	110/7206	3.31230403583e-17
ko04728	Dopaminergic synapse	65/856	185/7206	5.21254347615e-17
ko04723	Retrograde endocannabinoid signaling	60/856	175/7206	3.2244939054e-15
ko04727	GABAergic synapse	44/856	110/7206	3.3419543046e-14
ko04725	Cholinergic synapse	53/856	160/7206	6.84577907479e-13
ko04024	cAMP signaling pathway	74/856	279/7206	8.64155471879e-12
ko04921	Oxytocin signaling pathway	59/856	209/7206	6.63640304522e-11
ko04911	Insulin secretion	40/856	117/7206	1.6436971436e-10
ko04726	Serotonergic synapse	44/856	137/7206	2.04818869193e-10
ko04020	Calcium signaling pathway	68/856	265/7206	3.54258064034e-10
ko05031	Amphetamine addiction	32/856	91/7206	5.14180315569e-09
ko04744	Phototransduction	18/856	36/7206	2.09892032393e-08
ko04261	Adrenergic signaling in cardiomyocytes	51/856	205/7206	1.46445777551e-07
ko05322	Systemic lupus erythematosus	1/856	151/7206	1.5175906902e-07
ko04970	Salivary secretion	30/856	95/7206	2.44971671785e-07
ko04742	Taste transduction	22/856	61/7206	7.90514884235e-07
ko04060	Cytokine-cytokine receptor interaction	4/856	191/7206	1.11173072854e-06
ko05203	Viral carcinogenesis	10/856	277/7206	1.53191112214e-06
ko04720	Long-term potentiation	29/856	99/7206	2.21068952736e-06
ko03010	Ribosome	1/856	129/7206	2.8083740958e-06
ko03040	Spliceosome	2/856	145/7206	3.31861356355e-06
ko04120	Ubiquitin mediated proteolysis	2/856	138/7206	7.28682939182e-06
ko04925	Aldosterone synthesis and secretion	29/856	105/7206	9.58201149105e-06
ko04966	Collecting duct acid secretion	12/856	26/7206	1.44127213375e-05
ko05030	Cocaine addiction	22/856	73/7206	2.25483354842e-05
ko04971	Gastric acid secretion	26/856	98/7206	5.39598006995e-05
ko05168	Herpes simplex infection	6/856	182/7206	6.17264367834e-05
ko04745	Phototransduction - fly	14/856	38/7206	6.19958116753e-05
ko04730	Long-term depression	22/856	78/7206	6.96037575729e-05
ko03013	RNA transport	5/856	166/7206	7.77145721901e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	21/856	74/7206	9.18416060872e-05
ko04010	MAPK signaling pathway	61/856	321/7206	0.00013737429767
ko04022	cGMP-PKG signaling pathway	45/856	216/7206	0.000153270105547
ko05164	Influenza A	6/856	167/7206	0.000238233350661
ko05110	Vibrio cholerae infection	18/856	63/7206	0.000261818519189
ko04630	Jak-STAT signaling pathway	4/856	132/7206	0.000555133480839
ko04626	Plant-pathogen interaction	8/856	18/7206	0.000561765275336
ko04621	NOD-like receptor signaling pathway	6/856	157/7206	0.000650880550937
ko05166	HTLV-I infection	18/856	292/7206	0.00117651049243
ko03008	Ribosome biogenesis in eukaryotes	1/856	79/7206	0.00120980934992
ko04540	Gap junction	28/856	128/7206	0.001270659218
ko04740	Olfactory transduction	20/856	80/7206	0.00128547396472
ko04514	Cell adhesion molecules (CAMs)	28/856	130/7206	0.00145619303322
ko05162	Measles	4/856	120/7206	0.00153426829011
ko04972	Pancreatic secretion	25/856	111/7206	0.00155358378603
ko04070	Phosphatidylinositol signaling system	25/856	112/7206	0.00165843906542
ko04110	Cell cycle	6/856	145/7206	0.00171188329125
ko04510	Focal adhesion	14/856	240/7206	0.00217733100623
ko04260	Cardiac muscle contraction	22/856	98/7206	0.00254024120091
ko05205	Proteoglycans in cancer	17/856	271/7206	0.00282769427617
ko04141	Protein processing in endoplasmic reticulum	10/856	184/7206	0.00379745629115
ko05161	Hepatitis B	9/856	173/7206	0.00403239144014
ko05169	Epstein-Barr virus infection	12/856	206/7206	0.00433721493118
ko00010	Glycolysis / Gluconeogenesis	17/856	74/7206	0.00604750127131
ko04750	Inflammatory mediator regulation of TRP channels	25/856	122/7206	0.00658162373672
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/856	79/7206	0.00742974614222
ko04330	Notch signaling pathway	1/856	62/7206	0.00859521460415
ko04214	Apoptosis - fly	2/856	72/7206	0.00998048126439
ko04930	Type II diabetes mellitus	13/856	54/7206	0.0101309937795
ko05140	Leishmaniasis	2/856	75/7206	0.0104598448451
ko05215	Prostate cancer	5/856	111/7206	0.0114433607253
ko04922	Glucagon signaling pathway	25/856	128/7206	0.012155834554
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/856	59/7206	0.0129229170569
ko04072	Phospholipase D signaling pathway	35/856	197/7206	0.013574498805
ko04915	Estrogen signaling pathway	25/856	131/7206	0.0138864816692
ko05120	Epithelial cell signaling in Helicobacter pylori infection	19/856	92/7206	0.0140170862542
ko04710	Circadian rhythm	11/856	43/7206	0.0142170310092
ko00680	Methane metabolism	9/856	34/7206	0.0151497367271
ko04064	NF-kappa B signaling pathway	4/856	96/7206	0.0160267448903
ko00240	Pyrimidine metabolism	5/856	110/7206	0.0161985573099
ko04964	Proximal tubule bicarbonate reclamation	8/856	29/7206	0.0168189408809
ko04924	Renin secretion	18/856	86/7206	0.0171088893814
ko00280	Valine, leucine and isoleucine degradation	1/856	54/7206	0.017863803117
ko04014	Ras signaling pathway	46/856	279/7206	0.0182180732467
ko00480	Glutathione metabolism	1/856	55/7206	0.01849431998
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/856	14/7206	0.0186662603087
ko04610	Complement and coagulation cascades	3/856	79/7206	0.0217929496537
ko04360	Axon guidance	39/856	233/7206	0.0234184154587
ko04960	Aldosterone-regulated sodium reabsorption	10/856	41/7206	0.0246171164721
ko05200	Pathways in cancer	43/856	492/7206	0.0250912331471
ko04657	IL-17 signaling pathway	4/856	87/7206	0.0299124129148
ko01524	Platinum drug resistance	3/856	76/7206	0.0306124254683
ko04612	Antigen processing and presentation	3/856	77/7206	0.0312117027791
ko00710	Carbon fixation in photosynthetic organisms	7/856	27/7206	0.0342678683444
ko04550	Signaling pathways regulating pluripotency of stem cells	11/856	165/7206	0.0376266965767
ko05144	Malaria	1/856	45/7206	0.0376418106623
ko03420	Nucleotide excision repair	1/856	46/7206	0.0377237406541
ko05219	Bladder cancer	1/856	48/7206	0.0395615435922
ko05016	Huntington's disease	16/856	215/7206	0.0415658752631
ko00310	Lysine degradation	3/856	73/7206	0.0429333762039
ko04371	Apelin signaling pathway	30/856	177/7206	0.0444681600721
ko05323	Rheumatoid arthritis	17/856	89/7206	0.0457965423712
ko00562	Inositol phosphate metabolism	17/856	89/7206	0.0457965423712