ko pathway ratio_in_study ratio_in_pop p_value ko04724 Glutamatergic synapse 12/82 152/7206 1.16738862046e-07 ko04727 GABAergic synapse 7/82 110/7206 0.0002363752411 ko04911 Insulin secretion 7/82 117/7206 0.000345613355902 ko04022 cGMP-PKG signaling pathway 9/82 216/7206 0.0007250940656 ko04723 Retrograde endocannabinoid signaling 8/82 175/7206 0.000794813532157 ko04713 Circadian entrainment 7/82 136/7206 0.000855374837542 ko04925 Aldosterone synthesis and secretion 6/82 105/7206 0.00118525556163 ko05030 Cocaine addiction 5/82 73/7206 0.00138336372446 ko04261 Adrenergic signaling in cardiomyocytes 8/82 205/7206 0.00219338572122 ko04912 GnRH signaling pathway 6/82 122/7206 0.00255469065634 ko04924 Renin secretion 5/82 86/7206 0.00285913214162 ko04020 Calcium signaling pathway 9/82 265/7206 0.00300326358573 ko04915 Estrogen signaling pathway 6/82 131/7206 0.00364310304031 ko05033 Nicotine addiction 4/82 56/7206 0.00365103213822 ko05231 Choline metabolism in cancer 6/82 134/7206 0.00407307049998 ko00512 Mucin type O-glycan biosynthesis 3/82 29/7206 0.0041929426062 ko04360 Axon guidance 8/82 233/7206 0.00480842710059 ko04728 Dopaminergic synapse 7/82 185/7206 0.00492524846216 ko04080 Neuroactive ligand-receptor interaction 11/82 423/7206 0.00804558733326 ko05032 Morphine addiction 5/82 110/7206 0.00813266929409 ko04725 Cholinergic synapse 6/82 160/7206 0.00952697878101 ko04024 cAMP signaling pathway 8/82 279/7206 0.0136278236929 ko00562 Inositol phosphate metabolism 4/82 89/7206 0.0183126996668 ko05031 Amphetamine addiction 4/82 91/7206 0.0197081798723 ko04072 Phospholipase D signaling pathway 6/82 197/7206 0.0242972887102 ko04720 Long-term potentiation 4/82 99/7206 0.0259391771962 ko00564 Glycerophospholipid metabolism 4/82 99/7206 0.0259391771962 ko05010 Alzheimer's disease 6/82 202/7206 0.0270648956842 ko04270 Vascular smooth muscle contraction 5/82 154/7206 0.0305688044103 ko04921 Oxytocin signaling pathway 6/82 209/7206 0.0312816223366 ko05213 Endometrial cancer 3/82 62/7206 0.0332233955308 ko04070 Phosphatidylinositol signaling system 4/82 112/7206 0.0383487154716 ko05414 Dilated cardiomyopathy 4/82 112/7206 0.0383487154716 ko04320 Dorso-ventral axis formation 2/82 31/7206 0.0480780190656 ko04666 Fc gamma R-mediated phagocytosis 4/82 122/7206 0.0498601752255