ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	171/1014	423/7206	1.10952867595e-43
ko05033	Nicotine addiction	43/1014	56/7206	3.27224995719e-26
ko04724	Glutamatergic synapse	75/1014	152/7206	9.12505146686e-26
ko04721	Synaptic vesicle cycle	47/1014	80/7206	1.08427070517e-20
ko04728	Dopaminergic synapse	73/1014	185/7206	4.7793935939e-18
ko05032	Morphine addiction	52/1014	110/7206	3.69025918602e-17
ko04713	Circadian entrainment	59/1014	136/7206	4.36421411576e-17
ko04020	Calcium signaling pathway	87/1014	265/7206	1.96098662447e-15
ko04723	Retrograde endocannabinoid signaling	66/1014	175/7206	2.90775090944e-15
ko04921	Oxytocin signaling pathway	73/1014	209/7206	1.06099428446e-14
ko04725	Cholinergic synapse	61/1014	160/7206	1.90713313119e-14
ko04727	GABAergic synapse	48/1014	110/7206	3.02635540912e-14
ko04024	cAMP signaling pathway	84/1014	279/7206	1.76118271091e-12
ko04911	Insulin secretion	47/1014	117/7206	2.25287914283e-12
ko04726	Serotonergic synapse	51/1014	137/7206	8.09373198357e-12
ko04261	Adrenergic signaling in cardiomyocytes	65/1014	205/7206	5.77839529918e-11
ko04742	Taste transduction	29/1014	61/7206	3.26160031596e-10
ko05031	Amphetamine addiction	37/1014	91/7206	3.38243614677e-10
ko04720	Long-term potentiation	37/1014	99/7206	5.48370892971e-09
ko04970	Salivary secretion	36/1014	95/7206	5.72987553379e-09
ko04022	cGMP-PKG signaling pathway	59/1014	216/7206	2.35968192949e-07
ko04120	Ubiquitin mediated proteolysis	2/1014	138/7206	3.52193326429e-07
ko05168	Herpes simplex infection	5/1014	182/7206	3.75857433994e-07
ko03040	Spliceosome	3/1014	145/7206	1.33980866846e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	28/1014	79/7206	1.39801598352e-06
ko05203	Viral carcinogenesis	14/1014	277/7206	1.45007011267e-06
ko04966	Collecting duct acid secretion	14/1014	26/7206	2.0233496726e-06
ko04060	Cytokine-cytokine receptor interaction	7/1014	191/7206	2.42202146832e-06
ko05322	Systemic lupus erythematosus	4/1014	151/7206	2.64978637537e-06
ko04730	Long-term depression	27/1014	78/7206	3.62754941342e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	26/1014	74/7206	3.99693965833e-06
ko04010	MAPK signaling pathway	75/1014	321/7206	5.07319654836e-06
ko04260	Cardiac muscle contraction	31/1014	98/7206	6.44267001864e-06
ko04971	Gastric acid secretion	31/1014	98/7206	6.44267001864e-06
ko04744	Phototransduction	16/1014	36/7206	9.60234510013e-06
ko05030	Cocaine addiction	25/1014	73/7206	1.02798433623e-05
ko04745	Phototransduction - fly	16/1014	38/7206	2.2151651389e-05
ko04360	Axon guidance	56/1014	233/7206	3.26378671731e-05
ko04514	Cell adhesion molecules (CAMs)	36/1014	130/7206	3.60109115638e-05
ko04621	NOD-like receptor signaling pathway	6/1014	157/7206	3.64673988024e-05
ko04740	Olfactory transduction	25/1014	80/7206	6.5110327087e-05
ko04925	Aldosterone synthesis and secretion	30/1014	105/7206	9.41078823415e-05
ko03013	RNA transport	8/1014	166/7206	0.000163638474478
ko05164	Influenza A	8/1014	167/7206	0.000166389311327
ko04924	Renin secretion	25/1014	86/7206	0.000249631315395
ko04964	Proximal tubule bicarbonate reclamation	12/1014	29/7206	0.000289821292641
ko04626	Plant-pathogen interaction	9/1014	18/7206	0.000306771239117
ko05110	Vibrio cholerae infection	20/1014	63/7206	0.00032218454573
ko05010	Alzheimer's disease	47/1014	202/7206	0.000422430626161
ko04110	Cell cycle	7/1014	145/7206	0.000423217030788
ko04540	Gap junction	33/1014	128/7206	0.000431652468815
ko04214	Apoptosis - fly	1/1014	72/7206	0.000456928267868
ko04064	NF-kappa B signaling pathway	3/1014	96/7206	0.000569566333326
ko05410	Hypertrophic cardiomyopathy (HCM)	27/1014	100/7206	0.000675657295351
ko04972	Pancreatic secretion	29/1014	111/7206	0.000778924926984
ko04610	Complement and coagulation cascades	2/1014	79/7206	0.000953943380086
ko03008	Ribosome biogenesis in eukaryotes	2/1014	79/7206	0.000953943380086
ko04915	Estrogen signaling pathway	32/1014	131/7206	0.00135149643876
ko05205	Proteoglycans in cancer	21/1014	271/7206	0.00171803125197
ko00190	Oxidative phosphorylation	31/1014	127/7206	0.00175231384513
ko04146	Peroxisome	3/1014	89/7206	0.00177416133099
ko04371	Apelin signaling pathway	40/1014	177/7206	0.00199360707343
ko05140	Leishmaniasis	2/1014	75/7206	0.0021349342806
ko04750	Inflammatory mediator regulation of TRP channels	30/1014	122/7206	0.00220492642403
ko05414	Dilated cardiomyopathy	28/1014	112/7206	0.0022233662407
ko04070	Phosphatidylinositol signaling system	28/1014	112/7206	0.0022233662407
ko05166	HTLV-I infection	24/1014	292/7206	0.00252453773351
ko04014	Ras signaling pathway	57/1014	279/7206	0.00275994519402
ko04141	Protein processing in endoplasmic reticulum	13/1014	184/7206	0.00364642525842
ko04922	Glucagon signaling pathway	30/1014	128/7206	0.00433187017337
ko00520	Amino sugar and nucleotide sugar metabolism	1/1014	55/7206	0.00518343513023
ko00480	Glutathione metabolism	1/1014	55/7206	0.00518343513023
ko05161	Hepatitis B	12/1014	173/7206	0.00530098725108
ko00240	Pyrimidine metabolism	6/1014	110/7206	0.00551181044127
ko05169	Epstein-Barr virus infection	16/1014	206/7206	0.00598613604897
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/1014	59/7206	0.00745382953558
ko05162	Measles	7/1014	120/7206	0.00746370226839
ko00590	Arachidonic acid metabolism	1/1014	52/7206	0.00767456057153
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1014	14/7206	0.00836950748301
ko04330	Notch signaling pathway	2/1014	62/7206	0.0092033788463
ko05120	Epithelial cell signaling in Helicobacter pylori infection	22/1014	92/7206	0.0098085671537
ko00310	Lysine degradation	3/1014	73/7206	0.0102106044885
ko04115	p53 signaling pathway	3/1014	74/7206	0.0104599144466
ko00260	Glycine, serine and threonine metabolism	1/1014	48/7206	0.0109905396568
ko04630	Jak-STAT signaling pathway	9/1014	132/7206	0.0155269242717
ko03022	Basal transcription factors	1/1014	44/7206	0.0161826442963
ko05144	Malaria	1/1014	45/7206	0.0162811326303
ko00071	Fatty acid degradation	1/1014	45/7206	0.0162811326303
ko03420	Nucleotide excision repair	1/1014	46/7206	0.0167711721167
ko04930	Type II diabetes mellitus	14/1014	54/7206	0.0176470424816
ko05321	Inflammatory bowel disease (IBD)	2/1014	56/7206	0.0191485093849
ko04657	IL-17 signaling pathway	5/1014	87/7206	0.0197969827887
ko04612	Antigen processing and presentation	4/1014	77/7206	0.0203402586177
ko04072	Phospholipase D signaling pathway	39/1014	197/7206	0.0222780496551
ko00140	Steroid hormone biosynthesis	1/1014	41/7206	0.0239676410801
ko00983	Drug metabolism - other enzymes	1/1014	42/7206	0.0240793997458
ko00561	Glycerolipid metabolism	3/1014	63/7206	0.0283882597432
ko04640	Hematopoietic cell lineage	3/1014	64/7206	0.0286182532704
ko01524	Platinum drug resistance	4/1014	76/7206	0.0290623769094
ko00562	Inositol phosphate metabolism	20/1014	89/7206	0.0303543635375
ko05200	Pathways in cancer	53/1014	492/7206	0.0313450665448
ko04976	Bile secretion	18/1014	80/7206	0.0352792191382
ko03410	Base excision repair	1/1014	38/7206	0.0354190467419
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1014	40/7206	0.0364462418698
ko04916	Melanogenesis	29/1014	142/7206	0.0371854578523
ko00380	Tryptophan metabolism	2/1014	50/7206	0.0393473184923
ko04550	Signaling pathways regulating pluripotency of stem cells	14/1014	165/7206	0.0405669975954
ko04973	Carbohydrate digestion and absorption	11/1014	42/7206	0.0405687611796
ko04622	RIG-I-like receptor signaling pathway	3/1014	62/7206	0.0409114215651
ko00010	Glycolysis / Gluconeogenesis	17/1014	74/7206	0.0412950372765
ko04015	Rap1 signaling pathway	51/1014	278/7206	0.0426554949329
ko00710	Carbon fixation in photosynthetic organisms	8/1014	27/7206	0.0445939866356
ko05222	Small cell lung cancer	6/1014	89/7206	0.0454365427892
ko04217	Necroptosis	16/1014	178/7206	0.049139641473
ko05206	MicroRNAs in cancer	16/1014	177/7206	0.049160156273