ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	191/1186	423/7206	7.44542174108e-47
ko04724	Glutamatergic synapse	88/1186	152/7206	9.21726903504e-32
ko05033	Nicotine addiction	45/1186	56/7206	6.21447520817e-26
ko04713	Circadian entrainment	72/1186	136/7206	6.13105711323e-23
ko04727	GABAergic synapse	63/1186	110/7206	1.18584692117e-22
ko05032	Morphine addiction	62/1186	110/7206	8.32168914062e-22
ko04020	Calcium signaling pathway	101/1186	265/7206	5.61758150685e-18
ko04721	Synaptic vesicle cycle	47/1186	80/7206	8.10484574185e-18
ko04728	Dopaminergic synapse	79/1186	185/7206	1.04779848374e-17
ko04725	Cholinergic synapse	70/1186	160/7206	1.73279078833e-16
ko04024	cAMP signaling pathway	101/1186	279/7206	3.06213279447e-16
ko04911	Insulin secretion	56/1186	117/7206	1.58004139891e-15
ko04723	Retrograde endocannabinoid signaling	72/1186	175/7206	3.3539251492e-15
ko04921	Oxytocin signaling pathway	79/1186	209/7206	6.42340020152e-14
ko04726	Serotonergic synapse	59/1186	137/7206	1.02661198521e-13
ko04742	Taste transduction	34/1186	61/7206	2.47579351938e-12
ko04744	Phototransduction	24/1186	36/7206	2.12323018751e-11
ko05031	Amphetamine addiction	40/1186	91/7206	4.83917657897e-10
ko04970	Salivary secretion	41/1186	95/7206	5.82420975289e-10
ko04261	Adrenergic signaling in cardiomyocytes	68/1186	205/7206	2.43546946952e-09
ko03010	Ribosome	1/1186	129/7206	2.57288947714e-09
ko04720	Long-term potentiation	40/1186	99/7206	9.62393853373e-09
ko03040	Spliceosome	3/1186	145/7206	2.46006785511e-08
ko04022	cGMP-PKG signaling pathway	68/1186	216/7206	3.51004847592e-08
ko05168	Herpes simplex infection	7/1186	182/7206	1.38887630909e-07
ko05203	Viral carcinogenesis	17/1186	277/7206	2.20363040803e-07
ko05322	Systemic lupus erythematosus	5/1186	151/7206	5.88033113225e-07
ko04925	Aldosterone synthesis and secretion	37/1186	105/7206	3.28231795293e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	29/1186	74/7206	3.74785908876e-06
ko03013	RNA transport	8/1186	166/7206	6.18441850421e-06
ko05164	Influenza A	8/1186	167/7206	6.40509099447e-06
ko05030	Cocaine addiction	28/1186	73/7206	7.24560806811e-06
ko04730	Long-term depression	29/1186	78/7206	8.3194583276e-06
ko04060	Cytokine-cytokine receptor interaction	11/1186	191/7206	1.04320293273e-05
ko04966	Collecting duct acid secretion	14/1186	26/7206	1.34986394142e-05
ko04621	NOD-like receptor signaling pathway	8/1186	157/7206	1.75289080472e-05
ko04740	Olfactory transduction	29/1186	80/7206	2.22044674144e-05
ko04971	Gastric acid secretion	33/1186	98/7206	2.50321952204e-05
ko04070	Phosphatidylinositol signaling system	36/1186	112/7206	4.67582325608e-05
ko04120	Ubiquitin mediated proteolysis	7/1186	138/7206	6.49108871215e-05
ko04964	Proximal tubule bicarbonate reclamation	14/1186	29/7206	6.64434494004e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	27/1186	79/7206	9.71180242098e-05
ko04110	Cell cycle	8/1186	145/7206	9.74013492001e-05
ko04514	Cell adhesion molecules (CAMs)	39/1186	130/7206	0.000104626478266
ko04360	Axon guidance	61/1186	233/7206	0.000141623205909
ko04010	MAPK signaling pathway	79/1186	321/7206	0.000146544871301
ko04745	Phototransduction - fly	16/1186	38/7206	0.000156595380762
ko04260	Cardiac muscle contraction	31/1186	98/7206	0.00016810655005
ko03008	Ribosome biogenesis in eukaryotes	2/1186	79/7206	0.000173318221164
ko04972	Pancreatic secretion	34/1186	111/7206	0.000234336626361
ko04141	Protein processing in endoplasmic reticulum	13/1186	184/7206	0.0002487856293
ko05140	Leishmaniasis	2/1186	75/7206	0.000251458505775
ko05161	Hepatitis B	12/1186	173/7206	0.000251785119165
ko05162	Measles	6/1186	120/7206	0.000252320811126
ko04612	Antigen processing and presentation	2/1186	77/7206	0.000264963577571
ko05169	Epstein-Barr virus infection	16/1186	206/7206	0.000273281082589
ko04371	Apelin signaling pathway	48/1186	177/7206	0.000286713998524
ko04072	Phospholipase D signaling pathway	52/1186	197/7206	0.000400994711675
ko04064	NF-kappa B signaling pathway	4/1186	96/7206	0.000413926044423
ko05414	Dilated cardiomyopathy	33/1186	112/7206	0.000467478483858
ko05110	Vibrio cholerae infection	21/1186	63/7206	0.000907564202727
ko04014	Ras signaling pathway	67/1186	279/7206	0.000934601617654
ko04540	Gap junction	36/1186	128/7206	0.00100784033555
ko04610	Complement and coagulation cascades	3/1186	79/7206	0.00107547652642
ko04976	Bile secretion	25/1186	80/7206	0.0011497137016
ko04710	Circadian rhythm	16/1186	43/7206	0.00125249407536
ko05205	Proteoglycans in cancer	26/1186	271/7206	0.0014263519643
ko04924	Renin secretion	26/1186	86/7206	0.00177012772032
ko00562	Inositol phosphate metabolism	26/1186	89/7206	0.0022628227329
ko04930	Type II diabetes mellitus	18/1186	54/7206	0.00244315606645
ko05166	HTLV-I infection	30/1186	292/7206	0.00279014860388
ko04750	Inflammatory mediator regulation of TRP channels	33/1186	122/7206	0.00284770918845
ko05410	Hypertrophic cardiomyopathy (HCM)	28/1186	100/7206	0.00386318024277
ko03420	Nucleotide excision repair	1/1186	46/7206	0.00440935163356
ko04510	Focal adhesion	24/1186	240/7206	0.00454933502513
ko04350	TGF-beta signaling pathway	7/1186	103/7206	0.0048217829028
ko04626	Plant-pathogen interaction	8/1186	18/7206	0.00487591342415
ko04657	IL-17 signaling pathway	5/1186	87/7206	0.00509292382515
ko00520	Amino sugar and nucleotide sugar metabolism	2/1186	55/7206	0.00565192170223
ko05321	Inflammatory bowel disease (IBD)	2/1186	56/7206	0.0057387908898
ko04915	Estrogen signaling pathway	34/1186	131/7206	0.00579153421881
ko03022	Basal transcription factors	1/1186	44/7206	0.00671997025124
ko05145	Toxoplasmosis	10/1186	126/7206	0.00730083470987
ko00710	Carbon fixation in photosynthetic organisms	10/1186	27/7206	0.00802587439583
ko04330	Notch signaling pathway	3/1186	62/7206	0.00919128638856
ko04622	RIG-I-like receptor signaling pathway	3/1186	62/7206	0.00919128638856
ko04214	Apoptosis - fly	4/1186	72/7206	0.00968434928694
ko04217	Necroptosis	17/1186	178/7206	0.0102339435942
ko04922	Glucagon signaling pathway	32/1186	128/7206	0.01136964045
ko05200	Pathways in cancer	61/1186	492/7206	0.0116284803424
ko05133	Pertussis	6/1186	87/7206	0.0127752769913
ko03410	Base excision repair	1/1186	38/7206	0.0147989272586
ko05219	Bladder cancer	2/1186	48/7206	0.017612131668
ko04630	Jak-STAT signaling pathway	12/1186	132/7206	0.0178183508127
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1186	14/7206	0.0178773477486
ko00010	Glycolysis / Gluconeogenesis	20/1186	74/7206	0.0179633639155
ko04210	Apoptosis	18/1186	180/7206	0.0186660958599
ko00240	Pyrimidine metabolism	9/1186	110/7206	0.0187563890915
ko05131	Shigellosis	6/1186	82/7206	0.0236549246068
ko04142	Lysosome	15/1186	151/7206	0.0264629371128
ko05416	Viral myocarditis	3/1186	55/7206	0.0266825231624
ko04658	Th1 and Th2 cell differentiation	8/1186	96/7206	0.0267377469034
ko04146	Peroxisome	7/1186	89/7206	0.0296548475963
ko05222	Small cell lung cancer	7/1186	89/7206	0.0296548475963
ko04923	Regulation of lipolysis in adipocytes	20/1186	77/7206	0.0298719868556
ko05016	Huntington's disease	24/1186	215/7206	0.0317479177451
ko00860	Porphyrin and chlorophyll metabolism	1/1186	34/7206	0.0336665847305
ko04668	TNF signaling pathway	11/1186	120/7206	0.0337258271724
ko04960	Aldosterone-regulated sodium reabsorption	12/1186	41/7206	0.0340820223814
ko04113	Meiosis - yeast	5/1186	70/7206	0.0341930317448
ko04270	Vascular smooth muscle contraction	35/1186	154/7206	0.0371052377847
ko00590	Arachidonic acid metabolism	3/1186	52/7206	0.0373194159328
ko05215	Prostate cancer	10/1186	111/7206	0.0377896168569
ko05206	MicroRNAs in cancer	19/1186	177/7206	0.0395588314773
ko04620	Toll-like receptor signaling pathway	9/1186	100/7206	0.0415002777011
ko01524	Platinum drug resistance	6/1186	76/7206	0.0426380357575
ko05130	Pathogenic Escherichia coli infection	6/1186	77/7206	0.0430489779162
ko05010	Alzheimer's disease	44/1186	202/7206	0.0430833086904
ko00220	Arginine biosynthesis	8/1186	24/7206	0.046146316473
ko05340	Primary immunodeficiency	1/1186	30/7206	0.0490534230314