ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 31/304 191/7206 5.88964491331e-11 ko04650 Natural killer cell mediated cytotoxicity 20/304 97/7206 2.44345236689e-09 ko05340 Primary immunodeficiency 10/304 30/7206 2.1838090431e-07 ko04380 Osteoclast differentiation 20/304 134/7206 6.96327604476e-07 ko05320 Autoimmune thyroid disease 8/304 29/7206 1.80769706682e-05 ko05164 Influenza A 20/304 167/7206 2.17496597216e-05 ko04137 Mitophagy - animal 13/304 82/7206 3.34881010302e-05 ko04659 Th17 cell differentiation 15/304 106/7206 3.37946085756e-05 ko04630 Jak-STAT signaling pathway 17/304 132/7206 3.56076200643e-05 ko05162 Measles 16/304 120/7206 3.93175336371e-05 ko05330 Allograft rejection 7/304 24/7206 4.13194650428e-05 ko04660 T cell receptor signaling pathway 16/304 124/7206 5.90623465035e-05 ko05168 Herpes simplex infection 20/304 182/7206 7.55514407488e-05 ko05321 Inflammatory bowel disease (IBD) 10/304 56/7206 9.7462637203e-05 ko05145 Toxoplasmosis 15/304 126/7206 0.000250105329838 ko05140 Leishmaniasis 11/304 75/7206 0.000275086642779 ko04612 Antigen processing and presentation 11/304 77/7206 0.000348100860716 ko05144 Malaria 8/304 45/7206 0.000503770988359 ko04658 Th1 and Th2 cell differentiation 12/304 96/7206 0.000663052859067 ko05332 Graft-versus-host disease 5/304 18/7206 0.000703626655473 ko04672 Intestinal immune network for IgA production 7/304 37/7206 0.000766570111758 ko04620 Toll-like receptor signaling pathway 12/304 100/7206 0.000959147468675 ko05152 Tuberculosis 18/304 187/7206 0.00115683686818 ko00120 Primary bile acid biosynthesis 5/304 20/7206 0.00118774047168 ko05167 Kaposi's sarcoma-associated herpesvirus infection 18/304 191/7206 0.00135474939318 ko04610 Complement and coagulation cascades 10/304 79/7206 0.00167276753054 ko03050 Proteasome 8/304 54/7206 0.00174945974226 ko05150 Staphylococcus aureus infection 6/304 36/7206 0.00358278042983 ko04146 Peroxisome 10/304 89/7206 0.00407559038323 ko05323 Rheumatoid arthritis 10/304 89/7206 0.00407559038323 ko04611 Platelet activation 15/304 163/7206 0.0043930163932 ko05034 Alcoholism 2/304 238/7206 0.0045179526248 ko05310 Asthma 4/304 17/7206 0.00477853791111 ko04664 Fc epsilon RI signaling pathway 9/304 77/7206 0.00486050828111 ko04728 Dopaminergic synapse 1/304 185/7206 0.00490700354639 ko04640 Hematopoietic cell lineage 8/304 64/7206 0.0051715564876 ko04064 NF-kappa B signaling pathway 10/304 96/7206 0.00698089488646 ko04310 Wnt signaling pathway 1/304 181/7206 0.00736249315447 ko04621 NOD-like receptor signaling pathway 14/304 157/7206 0.00741822748276 ko00051 Fructose and mannose metabolism 6/304 42/7206 0.00781041275966 ko04145 Phagosome 14/304 162/7206 0.00917336775283 ko04940 Type I diabetes mellitus 5/304 32/7206 0.0101987578318 ko03013 RNA transport 1/304 166/7206 0.0103364368953 ko04068 FoxO signaling pathway 14/304 167/7206 0.0165967654875 ko00220 Arginine biosynthesis 4/304 24/7206 0.0169206578508 ko05161 Hepatitis B 14/304 173/7206 0.0189766943749 ko00590 Arachidonic acid metabolism 6/304 52/7206 0.0213651358588 ko04217 Necroptosis 14/304 178/7206 0.0218092555743 ko04080 Neuroactive ligand-receptor interaction 9/304 423/7206 0.0243097918072 ko04514 Cell adhesion molecules (CAMs) 11/304 130/7206 0.0245641961104 ko04530 Tight junction 3/304 228/7206 0.0271691310285 ko05416 Viral myocarditis 6/304 55/7206 0.0274106095563 ko05133 Pertussis 8/304 87/7206 0.0298052480902 ko04662 B cell receptor signaling pathway 8/304 88/7206 0.0316344494351 ko04916 Melanogenesis 1/304 142/7206 0.0317761531873 ko03040 Spliceosome 1/304 145/7206 0.0328090452956 ko04110 Cell cycle 1/304 145/7206 0.0328090452956 ko04710 Circadian rhythm 5/304 43/7206 0.0335302273634 ko04666 Fc gamma R-mediated phagocytosis 10/304 122/7206 0.0378529009258 ko04136 Autophagy - other 4/304 31/7206 0.0398416203853 ko00592 alpha-Linolenic acid metabolism 3/304 19/7206 0.0436574908762 ko03010 Ribosome 1/304 129/7206 0.0448288228049 ko04622 RIG-I-like receptor signaling pathway 6/304 62/7206 0.0456299986671