ko pathway ratio_in_study ratio_in_pop p_value ko04724 Glutamatergic synapse 23/154 152/7206 7.31894592307e-14 ko05033 Nicotine addiction 13/154 56/7206 9.98708566536e-11 ko04727 GABAergic synapse 13/154 110/7206 5.1871074629e-07 ko04744 Phototransduction 8/154 36/7206 6.60675176602e-07 ko04740 Olfactory transduction 11/154 80/7206 8.75256895957e-07 ko04723 Retrograde endocannabinoid signaling 15/154 175/7206 4.2964813697e-06 ko04728 Dopaminergic synapse 15/154 185/7206 8.51188854119e-06 ko04080 Neuroactive ligand-receptor interaction 24/154 423/7206 9.1833802909e-06 ko05032 Morphine addiction 11/154 110/7206 2.05331169504e-05 ko05030 Cocaine addiction 9/154 73/7206 2.22269350786e-05 ko04024 cAMP signaling pathway 17/154 279/7206 8.74342061415e-05 ko04974 Protein digestion and absorption 9/154 96/7206 0.000195400593664 ko04713 Circadian entrainment 10/154 136/7206 0.000628512701697 ko04725 Cholinergic synapse 10/154 160/7206 0.00217292571606 ko04726 Serotonergic synapse 9/154 137/7206 0.00256993047676 ko04911 Insulin secretion 8/154 117/7206 0.00345841082255 ko05014 Amyotrophic lateral sclerosis (ALS) 6/154 74/7206 0.0048408969416 ko04721 Synaptic vesicle cycle 6/154 80/7206 0.00707461662649 ko04742 Taste transduction 5/154 61/7206 0.00949806982489 ko00830 Retinol metabolism 4/154 42/7206 0.0119540023905 ko05031 Amphetamine addiction 6/154 91/7206 0.0129691077562 ko04020 Calcium signaling pathway 12/154 265/7206 0.0139637154321 ko04970 Salivary secretion 6/154 95/7206 0.0157807493056 ko04514 Cell adhesion molecules (CAMs) 7/154 130/7206 0.0210576089337 ko00512 Mucin type O-glycan biosynthesis 3/154 29/7206 0.0232920276276 ko05205 Proteoglycans in cancer 1/154 271/7206 0.031322180276 ko05034 Alcoholism 10/154 238/7206 0.0363466809666 ko02024 Quorum sensing 2/154 15/7206 0.0397114566221 ko01051 Biosynthesis of ansamycins 1/154 2/7206 0.0422883390225 ko04261 Adrenergic signaling in cardiomyocytes 9/154 205/7206 0.042430039527 ko04810 Regulation of actin cytoskeleton 1/154 264/7206 0.0465053403159