ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	185/1173	423/7206	1.38082684028e-43
ko04724	Glutamatergic synapse	90/1173	152/7206	6.35601250891e-34
ko05033	Nicotine addiction	47/1173	56/7206	6.77041879655e-29
ko04727	GABAergic synapse	66/1173	110/7206	1.42102871275e-25
ko05032	Morphine addiction	65/1173	110/7206	1.13263264711e-24
ko04713	Circadian entrainment	72/1173	136/7206	3.09881394789e-23
ko04728	Dopaminergic synapse	82/1173	185/7206	7.13267886527e-20
ko04725	Cholinergic synapse	73/1173	160/7206	1.1145329259e-18
ko04723	Retrograde endocannabinoid signaling	77/1173	175/7206	1.71189581176e-18
ko04721	Synaptic vesicle cycle	47/1173	80/7206	5.12145190183e-18
ko04024	cAMP signaling pathway	101/1173	279/7206	1.74376905879e-16
ko04020	Calcium signaling pathway	95/1173	265/7206	2.75558283887e-15
ko04744	Phototransduction	27/1173	36/7206	8.39997220414e-15
ko04726	Serotonergic synapse	59/1173	137/7206	6.21526479569e-14
ko04742	Taste transduction	35/1173	61/7206	2.59109298694e-13
ko04911	Insulin secretion	52/1173	117/7206	4.35292799806e-13
ko04921	Oxytocin signaling pathway	75/1173	209/7206	2.70775277384e-12
ko05031	Amphetamine addiction	41/1173	91/7206	7.99310836667e-11
ko04720	Long-term potentiation	42/1173	99/7206	4.8210493579e-10
ko03040	Spliceosome	2/1173	145/7206	4.04094098683e-09
ko03010	Ribosome	1/1173	129/7206	4.09232945467e-09
ko04970	Salivary secretion	39/1173	95/7206	6.27503593076e-09
ko04261	Adrenergic signaling in cardiomyocytes	65/1173	205/7206	2.55079184194e-08
ko04925	Aldosterone synthesis and secretion	40/1173	105/7206	5.64153178252e-08
ko05030	Cocaine addiction	31/1173	73/7206	8.95895953504e-08
ko04971	Gastric acid secretion	37/1173	98/7206	2.30126510554e-07
ko05322	Systemic lupus erythematosus	5/1173	151/7206	5.86131389801e-07
ko04070	Phosphatidylinositol signaling system	39/1173	112/7206	1.62369263148e-06
ko04740	Olfactory transduction	30/1173	80/7206	4.03794265129e-06
ko04621	NOD-like receptor signaling pathway	7/1173	157/7206	5.58085062564e-06
ko04022	cGMP-PKG signaling pathway	61/1173	216/7206	8.3249970494e-06
ko03013	RNA transport	8/1173	166/7206	9.19253929146e-06
ko04966	Collecting duct acid secretion	14/1173	26/7206	1.18346080797e-05
ko05168	Herpes simplex infection	10/1173	182/7206	1.46545603579e-05
ko04750	Inflammatory mediator regulation of TRP channels	39/1173	122/7206	1.6927126064e-05
ko04730	Long-term depression	28/1173	78/7206	1.97008466653e-05
ko05203	Viral carcinogenesis	21/1173	277/7206	1.98596657762e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	27/1173	74/7206	2.06231829747e-05
ko04972	Pancreatic secretion	36/1173	111/7206	2.24080149003e-05
ko04141	Protein processing in endoplasmic reticulum	11/1173	184/7206	2.83852464331e-05
ko04612	Antigen processing and presentation	1/1173	77/7206	3.13202732963e-05
ko04110	Cell cycle	7/1173	145/7206	3.29409202297e-05
ko04010	MAPK signaling pathway	80/1173	321/7206	5.12436321233e-05
ko04710	Circadian rhythm	18/1173	43/7206	5.78903546628e-05
ko04014	Ras signaling pathway	71/1173	279/7206	6.38782290093e-05
ko04072	Phospholipase D signaling pathway	54/1173	197/7206	7.51536027067e-05
ko04976	Bile secretion	27/1173	80/7206	0.000101587339297
ko04060	Cytokine-cytokine receptor interaction	13/1173	191/7206	0.000136204465646
ko04745	Phototransduction - fly	16/1173	38/7206	0.000136947311562
ko04514	Cell adhesion molecules (CAMs)	38/1173	130/7206	0.000170528744177
ko03008	Ribosome biogenesis in eukaryotes	2/1173	79/7206	0.000171640997083
ko05162	Measles	6/1173	120/7206	0.000245501811246
ko04540	Gap junction	37/1173	128/7206	0.000258008545085
ko05164	Influenza A	11/1173	167/7206	0.000267179619131
ko04120	Ubiquitin mediated proteolysis	8/1173	138/7206	0.000267322893765
ko05169	Epstein-Barr virus infection	16/1173	206/7206	0.000367053945068
ko04915	Estrogen signaling pathway	37/1173	131/7206	0.000465312940462
ko04924	Renin secretion	26/1173	86/7206	0.00105531951922
ko04964	Proximal tubule bicarbonate reclamation	12/1173	29/7206	0.00113145649718
ko00520	Amino sugar and nucleotide sugar metabolism	1/1173	55/7206	0.00135077874691
ko05140	Leishmaniasis	3/1173	75/7206	0.00150639102369
ko04960	Aldosterone-regulated sodium reabsorption	15/1173	41/7206	0.00196811264913
ko04930	Type II diabetes mellitus	18/1173	54/7206	0.00230613246538
ko05161	Hepatitis B	14/1173	173/7206	0.00232045843114
ko04923	Regulation of lipolysis in adipocytes	23/1173	77/7206	0.00271837567496
ko05110	Vibrio cholerae infection	20/1173	63/7206	0.00286874958576
ko05145	Toxoplasmosis	9/1173	126/7206	0.0032737450248
ko04922	Glucagon signaling pathway	34/1173	128/7206	0.00339664795179
ko04630	Jak-STAT signaling pathway	10/1173	132/7206	0.00413799895363
ko05414	Dilated cardiomyopathy	30/1173	112/7206	0.00421795488126
ko03420	Nucleotide excision repair	1/1173	46/7206	0.0044280186568
ko04626	Plant-pathogen interaction	8/1173	18/7206	0.00454572963722
ko05130	Pathogenic Escherichia coli infection	4/1173	77/7206	0.00485564533252
ko04064	NF-kappa B signaling pathway	6/1173	96/7206	0.00498763903265
ko04360	Axon guidance	54/1173	233/7206	0.00508597434439
ko04371	Apelin signaling pathway	43/1173	177/7206	0.00518234919862
ko05231	Choline metabolism in cancer	34/1173	134/7206	0.006270329669
ko03022	Basal transcription factors	1/1173	44/7206	0.00668367238053
ko00910	Nitrogen metabolism	8/1173	19/7206	0.00674753420345
ko04260	Cardiac muscle contraction	26/1173	98/7206	0.00849511454485
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/1173	79/7206	0.00851089779225
ko05416	Viral myocarditis	2/1173	55/7206	0.00880356953149
ko04330	Notch signaling pathway	3/1173	62/7206	0.00926918332428
ko04622	RIG-I-like receptor signaling pathway	3/1173	62/7206	0.00926918332428
ko05205	Proteoglycans in cancer	29/1173	271/7206	0.00929595051609
ko04711	Circadian rhythm - fly	6/1173	13/7206	0.0112142784791
ko05166	HTLV-I infection	32/1173	292/7206	0.011855804139
ko04510	Focal adhesion	25/1173	240/7206	0.0124309199826
ko05133	Pertussis	6/1173	87/7206	0.0128558136704
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/1173	59/7206	0.0128848755388
ko04217	Necroptosis	17/1173	178/7206	0.0131787988342
ko03410	Base excision repair	1/1173	38/7206	0.0149280573238
ko04658	Th1 and Th2 cell differentiation	7/1173	96/7206	0.0168952781919
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1173	14/7206	0.0169663287772
ko05219	Bladder cancer	2/1173	48/7206	0.0176163563013
ko00562	Inositol phosphate metabolism	23/1173	89/7206	0.0198669679084
ko04015	Rap1 signaling pathway	60/1173	278/7206	0.0199692593831
ko04672	Intestinal immune network for IgA production	1/1173	37/7206	0.0227926288079
ko05131	Shigellosis	6/1173	82/7206	0.02366662302
ko04115	p53 signaling pathway	5/1173	74/7206	0.0253844386179
ko05144	Malaria	2/1173	45/7206	0.0254913085115
ko04918	Thyroid hormone synthesis	22/1173	86/7206	0.0263186550743
ko00280	Valine, leucine and isoleucine degradation	3/1173	54/7206	0.0265466121072
ko05321	Inflammatory bowel disease (IBD)	3/1173	56/7206	0.0271228426034
ko04146	Peroxisome	7/1173	89/7206	0.0294457198015
ko00860	Porphyrin and chlorophyll metabolism	1/1173	34/7206	0.0334715065061
ko04142	Lysosome	15/1173	151/7206	0.0336888588177
ko04214	Apoptosis - fly	5/1173	72/7206	0.0351268796108
ko04114	Oocyte meiosis	32/1173	139/7206	0.0361626162485
ko04973	Carbohydrate digestion and absorption	12/1173	42/7206	0.0367487825472
ko00240	Pyrimidine metabolism	10/1173	110/7206	0.0373216915709
ko05016	Huntington's disease	24/1173	215/7206	0.0389087026672
ko04657	IL-17 signaling pathway	7/1173	87/7206	0.0394533090684
ko04210	Apoptosis	19/1173	180/7206	0.0400934284023
ko04350	TGF-beta signaling pathway	9/1173	103/7206	0.0423834840527
ko04912	GnRH signaling pathway	28/1173	122/7206	0.0480276182532
ko05206	MicroRNAs in cancer	19/1173	177/7206	0.0493428026829