ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	88/562	423/7206	1.22571414132e-18
ko04724	Glutamatergic synapse	48/562	152/7206	4.86953055028e-18
ko04721	Synaptic vesicle cycle	30/562	80/7206	5.95312906357e-14
ko04024	cAMP signaling pathway	59/562	279/7206	5.0053145082e-13
ko05032	Morphine addiction	33/562	110/7206	4.61232251566e-12
ko05033	Nicotine addiction	23/562	56/7206	5.82621166646e-12
ko04744	Phototransduction	18/562	36/7206	2.10491141864e-11
ko04727	GABAergic synapse	32/562	110/7206	2.44216339823e-11
ko04713	Circadian entrainment	36/562	136/7206	2.81290549457e-11
ko04728	Dopaminergic synapse	42/562	185/7206	1.32078619368e-10
ko04911	Insulin secretion	31/562	117/7206	6.76713282513e-10
ko04720	Long-term potentiation	28/562	99/7206	9.08521240153e-10
ko04723	Retrograde endocannabinoid signaling	39/562	175/7206	1.10407289521e-09
ko04020	Calcium signaling pathway	50/562	265/7206	2.62515060028e-09
ko04726	Serotonergic synapse	31/562	137/7206	4.05630142334e-08
ko05031	Amphetamine addiction	24/562	91/7206	6.52825857317e-08
ko04921	Oxytocin signaling pathway	40/562	209/7206	9.95492114413e-08
ko04261	Adrenergic signaling in cardiomyocytes	38/562	205/7206	3.85435061223e-07
ko04966	Collecting duct acid secretion	11/562	26/7206	1.54271581074e-06
ko04742	Taste transduction	17/562	61/7206	2.40616587555e-06
ko04970	Salivary secretion	22/562	95/7206	2.56482110106e-06
ko04060	Cytokine-cytokine receptor interaction	1/562	191/7206	6.29905759525e-06
ko05030	Cocaine addiction	18/562	73/7206	8.23119012471e-06
ko04725	Cholinergic synapse	29/562	160/7206	1.5395220898e-05
ko04745	Phototransduction - fly	12/562	38/7206	1.85007178639e-05
ko04070	Phosphatidylinositol signaling system	22/562	112/7206	4.17668198702e-05
ko04072	Phospholipase D signaling pathway	32/562	197/7206	6.32603859124e-05
ko05110	Vibrio cholerae infection	15/562	63/7206	7.20763074319e-05
ko05203	Viral carcinogenesis	6/562	277/7206	8.04507687092e-05
ko05322	Systemic lupus erythematosus	1/562	151/7206	9.23610656404e-05
ko05168	Herpes simplex infection	2/562	182/7206	0.000107298849914
ko04925	Aldosterone synthesis and secretion	20/562	105/7206	0.000144631159727
ko04010	MAPK signaling pathway	44/562	321/7206	0.000174794573132
ko04626	Plant-pathogen interaction	7/562	18/7206	0.00025132248455
ko04730	Long-term depression	16/562	78/7206	0.00027352780439
ko04022	cGMP-PKG signaling pathway	32/562	216/7206	0.000403345758271
ko05014	Amyotrophic lateral sclerosis (ALS)	15/562	74/7206	0.000482470503527
ko05169	Epstein-Barr virus infection	4/562	206/7206	0.000492283419188
ko03010	Ribosome	1/562	129/7206	0.000672520024422
ko04972	Pancreatic secretion	19/562	111/7206	0.00096858394468
ko04740	Olfactory transduction	15/562	80/7206	0.00113467266549
ko05164	Influenza A	3/562	167/7206	0.00115749141634
ko03040	Spliceosome	2/562	145/7206	0.00139832890513
ko05162	Measles	1/562	120/7206	0.00150491464573
ko04260	Cardiac muscle contraction	17/562	98/7206	0.00168533948242
ko04971	Gastric acid secretion	17/562	98/7206	0.00168533948242
ko05120	Epithelial cell signaling in Helicobacter pylori infection	16/562	92/7206	0.00234849400687
ko04514	Cell adhesion molecules (CAMs)	20/562	130/7206	0.00272441173116
ko04750	Inflammatory mediator regulation of TRP channels	19/562	122/7206	0.00321234270944
ko04110	Cell cycle	3/562	145/7206	0.00461348248867
ko04540	Gap junction	19/562	128/7206	0.00665279222652
ko05200	Pathways in cancer	23/562	492/7206	0.00668427260514
ko05166	HTLV-I infection	11/562	292/7206	0.00707376811218
ko04014	Ras signaling pathway	34/562	279/7206	0.00841352350891
ko04810	Regulation of actin cytoskeleton	10/562	264/7206	0.00985492186474
ko05010	Alzheimer's disease	26/562	202/7206	0.0107166844485
ko00190	Oxidative phosphorylation	18/562	127/7206	0.0114718551565
ko04960	Aldosterone-regulated sodium reabsorption	8/562	41/7206	0.0124849636453
ko00230	Purine metabolism	25/562	194/7206	0.0135173669784
ko00010	Glycolysis / Gluconeogenesis	12/562	74/7206	0.013722608074
ko04657	IL-17 signaling pathway	1/562	87/7206	0.0138960109845
ko04510	Focal adhesion	9/562	240/7206	0.0139345184164
ko00680	Methane metabolism	7/562	34/7206	0.0142512363234
ko03013	RNA transport	5/562	166/7206	0.0179142697794
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/562	14/7206	0.0194971311716
ko04964	Proximal tubule bicarbonate reclamation	6/562	29/7206	0.022176762534
ko04924	Renin secretion	13/562	86/7206	0.0226359739149
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/562	59/7206	0.0229945768619
ko04350	TGF-beta signaling pathway	2/562	103/7206	0.0238958768545
ko04120	Ubiquitin mediated proteolysis	4/562	138/7206	0.0244153058161
ko05323	Rheumatoid arthritis	13/562	89/7206	0.025836276015
ko00562	Inositol phosphate metabolism	13/562	89/7206	0.025836276015
ko04922	Glucagon signaling pathway	17/562	128/7206	0.0287292982453
ko05161	Hepatitis B	6/562	173/7206	0.0301741117666
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/562	79/7206	0.0308381785266
ko04064	NF-kappa B signaling pathway	2/562	96/7206	0.0328888332593
ko04978	Mineral absorption	7/562	40/7206	0.033011482924
ko04630	Jak-STAT signaling pathway	4/562	132/7206	0.0331944153363
ko04722	Neurotrophin signaling pathway	20/562	160/7206	0.0351003347175
ko04141	Protein processing in endoplasmic reticulum	7/562	184/7206	0.0365905903574
ko04146	Peroxisome	2/562	89/7206	0.0457663842584
ko05222	Small cell lung cancer	2/562	89/7206	0.0457663842584
ko04371	Apelin signaling pathway	21/562	177/7206	0.0466752084315
ko05034	Alcoholism	27/562	238/7206	0.0479687242527