ko pathway ratio_in_study ratio_in_pop p_value ko04721 Synaptic vesicle cycle 7/52 80/7206 1.42604403046e-06 ko04727 GABAergic synapse 7/52 110/7206 1.21123301533e-05 ko04961 Endocrine and other factor-regulated calcium reabsorption 5/52 59/7206 5.9961648025e-05 ko04261 Adrenergic signaling in cardiomyocytes 8/52 205/7206 9.59714151812e-05 ko04724 Glutamatergic synapse 7/52 152/7206 9.76577172886e-05 ko04015 Rap1 signaling pathway 9/52 278/7206 0.000142141500739 ko04530 Tight junction 8/52 228/7206 0.000200793892573 ko04728 Dopaminergic synapse 7/52 185/7206 0.000330412096186 ko04971 Gastric acid secretion 5/52 98/7206 0.000658002800455 ko04964 Proximal tubule bicarbonate reclamation 3/52 29/7206 0.00113454721371 ko04972 Pancreatic secretion 5/52 111/7206 0.00115722327304 ko04911 Insulin secretion 5/52 117/7206 0.0014643998907 ko04723 Retrograde endocannabinoid signaling 6/52 175/7206 0.00151760499454 ko04976 Bile secretion 4/52 80/7206 0.00254527821854 ko04918 Thyroid hormone synthesis 4/52 86/7206 0.00331063257922 ko04024 cAMP signaling pathway 7/52 279/7206 0.00363105121027 ko05120 Epithelial cell signaling in Helicobacter pylori infection 4/52 92/7206 0.0042200049939 ko04670 Leukocyte transendothelial migration 5/52 151/7206 0.00444830126946 ko04970 Salivary secretion 4/52 95/7206 0.00473244294681 ko05100 Bacterial invasion of epithelial cells 4/52 99/7206 0.00547883133643 ko04071 Sphingolipid signaling pathway 5/52 162/7206 0.00598474088514 ko04925 Aldosterone synthesis and secretion 4/52 105/7206 0.00674038362914 ko05032 Morphine addiction 4/52 110/7206 0.00792856763505 ko04962 Vasopressin-regulated water reabsorption 3/52 58/7206 0.00827175222765 ko05110 Vibrio cholerae infection 3/52 63/7206 0.0103804938162 ko04072 Phospholipase D signaling pathway 5/52 197/7206 0.0133234168293 ko04514 Cell adhesion molecules (CAMs) 4/52 130/7206 0.0140402928005 ko04062 Chemokine signaling pathway 5/52 201/7206 0.0144328288921 ko04966 Collecting duct acid secretion 2/52 26/7206 0.0148613318121 ko04713 Circadian entrainment 4/52 136/7206 0.0163292061883 ko04921 Oxytocin signaling pathway 5/52 209/7206 0.0168358475271 ko05131 Shigellosis 3/52 82/7206 0.0210410666365 ko05160 Hepatitis C 4/52 153/7206 0.0240444208589 ko04391 Hippo signaling pathway - fly 3/52 90/7206 0.0268161108063 ko04010 MAPK signaling pathway 6/52 321/7206 0.0270635223471 ko04725 Cholinergic synapse 4/52 160/7206 0.0277697345501 ko04145 Phagosome 4/52 162/7206 0.0288943406184 ko03015 mRNA surveillance pathway 3/52 93/7206 0.0291795553091 ko04341 Hedgehog signaling pathway - fly 2/52 38/7206 0.0304304898878 ko05132 Salmonella infection 3/52 98/7206 0.0333573297091 ko04978 Mineral absorption 2/52 40/7206 0.0334574082293 ko04960 Aldosterone-regulated sodium reabsorption 2/52 41/7206 0.0350134669082 ko04973 Carbohydrate digestion and absorption 2/52 42/7206 0.036597296836 ko04520 Adherens junction 3/52 103/7206 0.0378314157764 ko04371 Apelin signaling pathway 4/52 177/7206 0.0381949581678 ko04130 SNARE interactions in vesicular transport 2/52 44/7206 0.0398464156659 ko04810 Regulation of actin cytoskeleton 5/52 264/7206 0.0407106518739 ko04310 Wnt signaling pathway 4/52 181/7206 0.0409354835457 ko04014 Ras signaling pathway 5/52 279/7206 0.0496335138022