ko pathway ratio_in_study ratio_in_pop p_value ko04721 Synaptic vesicle cycle 27/336 80/7206 6.57059238222e-17 ko04724 Glutamatergic synapse 27/336 152/7206 1.26709972972e-09 ko04728 Dopaminergic synapse 30/336 185/7206 1.45226593195e-09 ko05033 Nicotine addiction 14/336 56/7206 1.71305442005e-07 ko04713 Circadian entrainment 21/336 136/7206 1.06550038778e-06 ko04723 Retrograde endocannabinoid signaling 24/336 175/7206 1.64809620535e-06 ko04514 Cell adhesion molecules (CAMs) 20/336 130/7206 2.05050720245e-06 ko04727 GABAergic synapse 18/336 110/7206 2.71217176291e-06 ko05032 Morphine addiction 18/336 110/7206 2.71217176291e-06 ko04024 cAMP signaling pathway 31/336 279/7206 6.34559473672e-06 ko04911 Insulin secretion 18/336 117/7206 6.69948003735e-06 ko05203 Viral carcinogenesis 1/336 277/7206 3.30237714935e-05 ko00604 Glycosphingolipid biosynthesis - ganglio series 5/336 14/7206 0.000302200014837 ko05205 Proteoglycans in cancer 2/336 271/7206 0.000345907066814 ko04725 Cholinergic synapse 18/336 160/7206 0.000440189717963 ko05030 Cocaine addiction 11/336 73/7206 0.000509161914123 ko04726 Serotonergic synapse 16/336 137/7206 0.000600405288012 ko04080 Neuroactive ligand-receptor interaction 35/336 423/7206 0.000778587823234 ko04966 Collecting duct acid secretion 6/336 26/7206 0.00102314717 ko04744 Phototransduction 7/336 36/7206 0.00116508164691 ko04144 Endocytosis 29/336 342/7206 0.00147801876215 ko05110 Vibrio cholerae infection 9/336 63/7206 0.00238582987882 ko05164 Influenza A 1/336 167/7206 0.00486295362363 ko04972 Pancreatic secretion 12/336 111/7206 0.00535665718503 ko05169 Epstein-Barr virus infection 2/336 206/7206 0.00634586425739 ko04360 Axon guidance 20/336 233/7206 0.00696396140522 ko04611 Platelet activation 1/336 163/7206 0.00723381294673 ko04140 Autophagy - animal 1/336 164/7206 0.00731972733564 ko05031 Amphetamine addiction 10/336 91/7206 0.00949070552287 ko04010 MAPK signaling pathway 25/336 321/7206 0.00986674713748 ko04964 Proximal tubule bicarbonate reclamation 5/336 29/7206 0.0100835285343 ko04261 Adrenergic signaling in cardiomyocytes 18/336 205/7206 0.0101881745544 ko05120 Epithelial cell signaling in Helicobacter pylori infection 10/336 92/7206 0.0102218836876 ko05322 Systemic lupus erythematosus 1/336 151/7206 0.0102597807345 ko04970 Salivary secretion 10/336 95/7206 0.0126741722523 ko03040 Spliceosome 1/336 145/7206 0.0150605282413 ko04940 Type I diabetes mellitus 5/336 32/7206 0.0152602451494 ko05014 Amyotrophic lateral sclerosis (ALS) 8/336 74/7206 0.0212266691314 ko04630 Jak-STAT signaling pathway 1/336 132/7206 0.0214419361856 ko04068 FoxO signaling pathway 2/336 167/7206 0.0247648726903 ko04072 Phospholipase D signaling pathway 16/336 197/7206 0.025595573967 ko02024 Quorum sensing 3/336 15/7206 0.0301129649994 ko00533 Glycosaminoglycan biosynthesis - keratan sulfate 3/336 15/7206 0.0301129649994 ko05166 HTLV-I infection 6/336 292/7206 0.0319560979917 ko04621 NOD-like receptor signaling pathway 2/336 157/7206 0.0346925997066 ko00513 Various types of N-glycan biosynthesis 5/336 42/7206 0.0442695994769 ko05162 Measles 1/336 120/7206 0.0454233197177 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/336 1/7206 0.0466278101584 ko05168 Herpes simplex infection 3/336 182/7206 0.048881013322 ko04932 Non-alcoholic fatty liver disease (NAFLD) 3/336 182/7206 0.048881013322 ko04720 Long-term potentiation 9/336 99/7206 0.0492753038432