ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	165/845	423/7206	5.18732036325e-51
ko05033	Nicotine addiction	48/845	56/7206	3.53233436703e-37
ko04724	Glutamatergic synapse	80/845	152/7206	1.00492734713e-35
ko04727	GABAergic synapse	58/845	110/7206	3.72323733143e-26
ko05032	Morphine addiction	58/845	110/7206	3.72323733143e-26
ko04713	Circadian entrainment	61/845	136/7206	1.23831636546e-22
ko04728	Dopaminergic synapse	71/845	185/7206	2.44082441975e-21
ko04723	Retrograde endocannabinoid signaling	68/845	175/7206	7.93510952292e-21
ko04725	Cholinergic synapse	61/845	160/7206	2.66593332759e-18
ko04024	cAMP signaling pathway	84/845	279/7206	2.77278047871e-17
ko04721	Synaptic vesicle cycle	39/845	80/7206	2.02193512274e-16
ko04020	Calcium signaling pathway	77/845	265/7206	7.98569202882e-15
ko04911	Insulin secretion	46/845	117/7206	1.13460603589e-14
ko04742	Taste transduction	31/845	61/7206	6.02553982476e-14
ko04726	Serotonergic synapse	49/845	137/7206	1.16029158827e-13
ko05031	Amphetamine addiction	37/845	91/7206	1.41797438399e-12
ko04921	Oxytocin signaling pathway	60/845	209/7206	1.49325142586e-11
ko04720	Long-term potentiation	37/845	99/7206	2.82796393335e-11
ko04261	Adrenergic signaling in cardiomyocytes	57/845	205/7206	1.62434331534e-10
ko05030	Cocaine addiction	28/845	73/7206	3.78345777009e-09
ko04970	Salivary secretion	32/845	95/7206	1.24864506785e-08
ko04744	Phototransduction	18/845	36/7206	1.70812221701e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	27/845	74/7206	2.52977287163e-08
ko03040	Spliceosome	1/845	145/7206	3.53069235203e-07
ko05203	Viral carcinogenesis	9/845	277/7206	4.93319966885e-07
ko04010	MAPK signaling pathway	68/845	321/7206	7.47441831105e-07
ko04060	Cytokine-cytokine receptor interaction	4/845	191/7206	1.10005822869e-06
ko04925	Aldosterone synthesis and secretion	30/845	105/7206	2.00358372555e-06
ko05164	Influenza A	3/845	167/7206	2.41576528837e-06
ko05168	Herpes simplex infection	4/845	182/7206	3.40784830352e-06
ko04022	cGMP-PKG signaling pathway	49/845	216/7206	4.30028359154e-06
ko04260	Cardiac muscle contraction	27/845	98/7206	1.80905108157e-05
ko04971	Gastric acid secretion	27/845	98/7206	1.80905108157e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/845	79/7206	2.22515382765e-05
ko04072	Phospholipase D signaling pathway	44/845	197/7206	2.3451468245e-05
ko04972	Pancreatic secretion	29/845	111/7206	3.3950302353e-05
ko04514	Cell adhesion molecules (CAMs)	32/845	130/7206	4.158697399e-05
ko04730	Long-term depression	22/845	78/7206	5.71378201641e-05
ko04120	Ubiquitin mediated proteolysis	3/845	138/7206	7.53151262154e-05
ko05322	Systemic lupus erythematosus	4/845	151/7206	9.3939009604e-05
ko04924	Renin secretion	23/845	86/7206	0.000117127469468
ko04621	NOD-like receptor signaling pathway	5/845	157/7206	0.000221121157097
ko04740	Olfactory transduction	21/845	80/7206	0.000298831749936
ko03013	RNA transport	6/845	166/7206	0.000337624859566
ko05169	Epstein-Barr virus infection	9/845	206/7206	0.000375243000027
ko04540	Gap junction	29/845	128/7206	0.000415027139839
ko05162	Measles	3/845	120/7206	0.000468251975672
ko05414	Dilated cardiomyopathy	26/845	112/7206	0.000522188175313
ko04070	Phosphatidylinositol signaling system	26/845	112/7206	0.000522188175313
ko04350	TGF-beta signaling pathway	2/845	103/7206	0.000526579891304
ko04110	Cell cycle	5/845	145/7206	0.000608559359261
ko04141	Protein processing in endoplasmic reticulum	8/845	184/7206	0.000683867953484
ko04745	Phototransduction - fly	12/845	38/7206	0.000927936198734
ko04612	Antigen processing and presentation	1/845	77/7206	0.00113847997562
ko03008	Ribosome biogenesis in eukaryotes	1/845	79/7206	0.00116947158428
ko04550	Signaling pathways regulating pluripotency of stem cells	7/845	165/7206	0.0012891369356
ko05205	Proteoglycans in cancer	16/845	271/7206	0.00141344037919
ko04214	Apoptosis - fly	1/845	72/7206	0.00256323042741
ko04014	Ras signaling pathway	49/845	279/7206	0.00315434427597
ko03018	RNA degradation	2/845	84/7206	0.00334839798084
ko04915	Estrogen signaling pathway	27/845	131/7206	0.0035155872892
ko00240	Pyrimidine metabolism	4/845	110/7206	0.0042706266111
ko05215	Prostate cancer	4/845	111/7206	0.0042887326588
ko04964	Proximal tubule bicarbonate reclamation	9/845	29/7206	0.00456113947362
ko05161	Hepatitis B	9/845	173/7206	0.00550197795204
ko04510	Focal adhesion	15/845	240/7206	0.00563240274558
ko04630	Jak-STAT signaling pathway	6/845	132/7206	0.00608343293115
ko04210	Apoptosis	10/845	180/7206	0.00667890385751
ko05166	HTLV-I infection	20/845	292/7206	0.00685125454175
ko04360	Axon guidance	41/845	233/7206	0.00688606187216
ko05410	Hypertrophic cardiomyopathy (HCM)	21/845	100/7206	0.00703756207519
ko04610	Complement and coagulation cascades	2/845	79/7206	0.00720502956721
ko04976	Bile secretion	18/845	80/7206	0.00746926183426
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/845	59/7206	0.00767106455233
ko04966	Collecting duct acid secretion	8/845	26/7206	0.00781068740817
ko04330	Notch signaling pathway	1/845	62/7206	0.00837437606103
ko04750	Inflammatory mediator regulation of TRP channels	24/845	122/7206	0.00991258037938
ko00310	Lysine degradation	2/845	73/7206	0.0100356517636
ko04146	Peroxisome	3/845	89/7206	0.0115297948737
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/845	182/7206	0.0137632442433
ko04064	NF-kappa B signaling pathway	4/845	96/7206	0.0159199820087
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/845	14/7206	0.0177117279891
ko00480	Glutathione metabolism	1/845	55/7206	0.0181132420244
ko04923	Regulation of lipolysis in adipocytes	16/845	77/7206	0.0194387113343
ko04140	Autophagy - animal	10/845	164/7206	0.0195421178607
ko05231	Choline metabolism in cancer	25/845	134/7206	0.0200109159526
ko04668	TNF signaling pathway	6/845	120/7206	0.0207857764021
ko05200	Pathways in cancer	42/845	492/7206	0.0241209537363
ko01200	Carbon metabolism	7/845	128/7206	0.0255181920278
ko04973	Carbohydrate digestion and absorption	10/845	42/7206	0.0259349342544
ko05010	Alzheimer's disease	34/845	202/7206	0.0263385757762
ko00590	Arachidonic acid metabolism	1/845	52/7206	0.027023252263
ko04930	Type II diabetes mellitus	12/845	54/7206	0.0298124748217
ko05222	Small cell lung cancer	4/845	89/7206	0.0301065780092
ko05140	Leishmaniasis	3/845	75/7206	0.0304339443528
ko01524	Platinum drug resistance	3/845	76/7206	0.0304464899446
ko05034	Alcoholism	39/845	238/7206	0.030701927986
ko04371	Apelin signaling pathway	30/845	177/7206	0.0331449035206
ko04912	GnRH signaling pathway	22/845	122/7206	0.0334618180242
ko04217	Necroptosis	12/845	178/7206	0.0336177901694
ko00620	Pyruvate metabolism	1/845	46/7206	0.0377628357579
ko03420	Nucleotide excision repair	1/845	46/7206	0.0377628357579
ko05202	Transcriptional misregulation in cancer	13/845	188/7206	0.0380585360002
ko00260	Glycine, serine and threonine metabolism	1/845	48/7206	0.0389174375956
ko05220	Chronic myeloid leukemia	4/845	85/7206	0.0410425207325
ko04657	IL-17 signaling pathway	4/845	87/7206	0.0419509322226
ko05110	Vibrio cholerae infection	13/845	63/7206	0.0453702048447
ko04150	mTOR signaling pathway	13/845	184/7206	0.0478705672151