ko pathway ratio_in_study ratio_in_pop p_value ko05340 Primary immunodeficiency 12/179 30/7206 2.23803711569e-12 ko05152 Tuberculosis 25/179 187/7206 3.40127457245e-12 ko04380 Osteoclast differentiation 20/179 134/7206 7.66647408151e-11 ko04060 Cytokine-cytokine receptor interaction 23/179 191/7206 2.33318982235e-10 ko04650 Natural killer cell mediated cytotoxicity 16/179 97/7206 1.47538726323e-09 ko05145 Toxoplasmosis 18/179 126/7206 1.49703886904e-09 ko04612 Antigen processing and presentation 14/179 77/7206 4.392435755e-09 ko05150 Staphylococcus aureus infection 10/179 36/7206 1.01107615009e-08 ko05140 Leishmaniasis 13/179 75/7206 2.93034092874e-08 ko04659 Th17 cell differentiation 15/179 106/7206 4.24601352301e-08 ko04621 NOD-like receptor signaling pathway 18/179 157/7206 5.21775817584e-08 ko04064 NF-kappa B signaling pathway 14/179 96/7206 8.28856274872e-08 ko05164 Influenza A 18/179 167/7206 1.36003793878e-07 ko05162 Measles 15/179 120/7206 2.28688582548e-07 ko04660 T cell receptor signaling pathway 15/179 124/7206 3.53593579639e-07 ko05168 Herpes simplex infection 18/179 182/7206 5.0127529208e-07 ko05321 Inflammatory bowel disease (IBD) 10/179 56/7206 9.20791644434e-07 ko05144 Malaria 9/179 45/7206 1.20783559939e-06 ko05330 Allograft rejection 7/179 24/7206 1.25690819746e-06 ko05320 Autoimmune thyroid disease 7/179 29/7206 5.1022662885e-06 ko04620 Toll-like receptor signaling pathway 12/179 100/7206 5.97389018398e-06 ko04630 Jak-STAT signaling pathway 13/179 132/7206 2.16913927916e-05 ko04658 Th1 and Th2 cell differentiation 11/179 96/7206 2.30151539639e-05 ko04640 Hematopoietic cell lineage 9/179 64/7206 2.50073886653e-05 ko05310 Asthma 5/179 17/7206 4.34259578323e-05 ko04145 Phagosome 14/179 162/7206 4.56982817017e-05 ko05133 Pertussis 10/179 87/7206 5.31594282551e-05 ko05332 Graft-versus-host disease 5/179 18/7206 5.89245313568e-05 ko04610 Complement and coagulation cascades 9/179 79/7206 0.000135720280915 ko04672 Intestinal immune network for IgA production 6/179 37/7206 0.000264682261863 ko05167 Kaposi's sarcoma-associated herpesvirus infection 14/179 191/7206 0.000267536030752 ko04662 B cell receptor signaling pathway 9/179 88/7206 0.000311089964844 ko03050 Proteasome 7/179 54/7206 0.00034289490891 ko05161 Hepatitis B 13/179 173/7206 0.000348919215018 ko05142 Chagas disease (American trypanosomiasis) 11/179 130/7206 0.000364962696695 ko04514 Cell adhesion molecules (CAMs) 11/179 130/7206 0.000364962696695 ko05416 Viral myocarditis 7/179 55/7206 0.000384783491858 ko04062 Chemokine signaling pathway 14/179 201/7206 0.000451267881177 ko04217 Necroptosis 13/179 178/7206 0.000459672549084 ko04666 Fc gamma R-mediated phagocytosis 10/179 122/7206 0.000865969852867 ko05131 Shigellosis 8/179 82/7206 0.000921436712613 ko04940 Type I diabetes mellitus 5/179 32/7206 0.00104460672584 ko05166 HTLV-I infection 17/179 292/7206 0.00145304269797 ko04622 RIG-I-like receptor signaling pathway 6/179 62/7206 0.00419416330593 ko05160 Hepatitis C 10/179 153/7206 0.00465798331942 ko04210 Apoptosis 11/179 180/7206 0.00507436805637 ko05323 Rheumatoid arthritis 7/179 89/7206 0.00645025927912 ko05132 Salmonella infection 7/179 98/7206 0.0107588735557 ko05146 Amoebiasis 7/179 99/7206 0.0113418226092 ko04664 Fc epsilon RI signaling pathway 6/179 77/7206 0.0119292209263 ko04144 Endocytosis 16/179 342/7206 0.0122642771114 ko04670 Leukocyte transendothelial migration 9/179 151/7206 0.0126835248074 ko04668 TNF signaling pathway 7/179 120/7206 0.0294832444173 ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series 3/179 28/7206 0.0313140996871 ko04142 Lysosome 8/179 151/7206 0.0340706216006 ko05100 Bacterial invasion of epithelial cells 6/179 99/7206 0.0362179750625 ko05169 Epstein-Barr virus infection 10/179 206/7206 0.0374112564233 ko05130 Pathogenic Escherichia coli infection 5/179 77/7206 0.0420578147593 ko05143 African trypanosomiasis 3/179 32/7206 0.0441352430928 ko05016 Huntington's disease 1/179 215/7206 0.0453256601022