ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 41/289 191/7206 1.6346582422e-19 ko05321 Inflammatory bowel disease (IBD) 19/289 56/7206 1.78743766073e-13 ko04380 Osteoclast differentiation 28/289 134/7206 2.68349053327e-13 ko04650 Natural killer cell mediated cytotoxicity 24/289 97/7206 2.88965513589e-13 ko05145 Toxoplasmosis 27/289 126/7206 3.84312816684e-13 ko05140 Leishmaniasis 21/289 75/7206 6.73236542007e-13 ko05330 Allograft rejection 13/289 24/7206 8.94158959964e-13 ko05152 Tuberculosis 32/289 187/7206 1.64480649355e-12 ko05340 Primary immunodeficiency 13/289 30/7206 3.45147405263e-11 ko05164 Influenza A 28/289 167/7206 7.33020171037e-11 ko04621 NOD-like receptor signaling pathway 27/289 157/7206 8.93946452771e-11 ko05168 Herpes simplex infection 29/289 182/7206 1.18295478649e-10 ko05162 Measles 23/289 120/7206 2.51982951246e-10 ko05332 Graft-versus-host disease 10/289 18/7206 3.03976175721e-10 ko05150 Staphylococcus aureus infection 13/289 36/7206 5.35852899964e-10 ko04612 Antigen processing and presentation 18/289 77/7206 8.18864113261e-10 ko04659 Th17 cell differentiation 20/289 106/7206 5.17647601334e-09 ko05320 Autoimmune thyroid disease 11/289 29/7206 6.49178014169e-09 ko04630 Jak-STAT signaling pathway 22/289 132/7206 9.78886554942e-09 ko05144 Malaria 13/289 45/7206 1.22214325504e-08 ko04658 Th1 and Th2 cell differentiation 18/289 96/7206 3.42977045526e-08 ko05310 Asthma 8/289 17/7206 1.07844763386e-07 ko04672 Intestinal immune network for IgA production 11/289 37/7206 1.20334735384e-07 ko04640 Hematopoietic cell lineage 14/289 64/7206 1.59651466214e-07 ko04940 Type I diabetes mellitus 10/289 32/7206 2.71559282399e-07 ko04620 Toll-like receptor signaling pathway 17/289 100/7206 3.67536773907e-07 ko04660 T cell receptor signaling pathway 19/289 124/7206 4.05315742298e-07 ko04064 NF-kappa B signaling pathway 16/289 96/7206 1.07701622154e-06 ko05133 Pertussis 15/289 87/7206 1.50682884863e-06 ko04217 Necroptosis 22/289 178/7206 2.17284166978e-06 ko04145 Phagosome 20/289 162/7206 6.49306093971e-06 ko05167 Kaposi's sarcoma-associated herpesvirus infection 21/289 191/7206 2.33786397939e-05 ko05323 Rheumatoid arthritis 13/289 89/7206 4.80643294193e-05 ko05142 Chagas disease (American trypanosomiasis) 16/289 130/7206 5.7545675293e-05 ko04610 Complement and coagulation cascades 12/289 79/7206 6.3441677108e-05 ko04062 Chemokine signaling pathway 20/289 201/7206 0.000149992693366 ko04622 RIG-I-like receptor signaling pathway 10/289 62/7206 0.00015555692814 ko05161 Hepatitis B 18/289 173/7206 0.000183548949851 ko04662 B cell receptor signaling pathway 12/289 88/7206 0.000184290362516 ko04514 Cell adhesion molecules (CAMs) 14/289 130/7206 0.00067265681366 ko04611 Platelet activation 16/289 163/7206 0.000795780480462 ko04623 Cytosolic DNA-sensing pathway 7/289 41/7206 0.0010787256732 ko05034 Alcoholism 1/289 238/7206 0.00110227244535 ko03050 Proteasome 8/289 54/7206 0.00126624326318 ko05416 Viral myocarditis 8/289 55/7206 0.00143129059467 ko05143 African trypanosomiasis 6/289 32/7206 0.00148207816747 ko05132 Salmonella infection 11/289 98/7206 0.00178706617146 ko05016 Huntington's disease 1/289 215/7206 0.00232120129801 ko04670 Leukocyte transendothelial migration 14/289 151/7206 0.00285870779975 ko04666 Fc gamma R-mediated phagocytosis 12/289 122/7206 0.00346426694113 ko04664 Fc epsilon RI signaling pathway 9/289 77/7206 0.00348372554759 ko05160 Hepatitis C 14/289 153/7206 0.00500659313471 ko04360 Axon guidance 2/289 233/7206 0.00625794749811 ko00120 Primary bile acid biosynthesis 4/289 20/7206 0.00738049039163 ko04310 Wnt signaling pathway 1/289 181/7206 0.0107712300603 ko04550 Signaling pathways regulating pluripotency of stem cells 1/289 165/7206 0.0150126365576 ko04910 Insulin signaling pathway 1/289 172/7206 0.0157539218347 ko05131 Shigellosis 8/289 82/7206 0.0165480483717 ko04137 Mitophagy - animal 8/289 82/7206 0.0165480483717 ko05146 Amoebiasis 9/289 99/7206 0.0174355526607 ko04210 Apoptosis 14/289 180/7206 0.0181658348756 ko05166 HTLV-I infection 20/289 292/7206 0.0206382360065 ko04152 AMPK signaling pathway 1/289 161/7206 0.0224656586618 ko00051 Fructose and mannose metabolism 5/289 42/7206 0.0253233118096 ko05169 Epstein-Barr virus infection 15/289 206/7206 0.0276446718955 ko03040 Spliceosome 1/289 145/7206 0.0312350221246 ko04110 Cell cycle 1/289 145/7206 0.0312350221246 ko04724 Glutamatergic synapse 1/289 152/7206 0.0326990961909 ko04390 Hippo signaling pathway 2/289 188/7206 0.0355882115363 ko04020 Calcium signaling pathway 4/289 265/7206 0.0359279225644 ko04713 Circadian entrainment 1/289 136/7206 0.0449943545958 ko05206 MicroRNAs in cancer 2/289 177/7206 0.0494797320901