ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	139/694	423/7206	3.82605894107e-43
ko05033	Nicotine addiction	40/694	56/7206	7.36673303938e-29
ko04724	Glutamatergic synapse	59/694	152/7206	1.73050201531e-22
ko05032	Morphine addiction	43/694	110/7206	8.29783945097e-17
ko04728	Dopaminergic synapse	56/694	185/7206	1.19864879404e-15
ko04727	GABAergic synapse	41/694	110/7206	3.16218092636e-15
ko04723	Retrograde endocannabinoid signaling	50/694	175/7206	5.25097405159e-13
ko04024	cAMP signaling pathway	67/694	279/7206	8.12239916876e-13
ko04713	Circadian entrainment	42/694	136/7206	2.40427536769e-12
ko04721	Synaptic vesicle cycle	31/694	80/7206	2.42569742917e-12
ko04725	Cholinergic synapse	44/694	160/7206	5.59998758802e-11
ko05030	Cocaine addiction	26/694	73/7206	1.27630489458e-09
ko04742	Taste transduction	23/694	61/7206	3.22021520391e-09
ko04911	Insulin secretion	33/694	117/7206	7.47581609119e-09
ko05014	Amyotrophic lateral sclerosis (ALS)	24/694	74/7206	4.557463746e-08
ko04726	Serotonergic synapse	34/694	137/7206	1.44096219208e-07
ko04360	Axon guidance	48/694	233/7206	3.38348601322e-07
ko04261	Adrenergic signaling in cardiomyocytes	43/694	205/7206	7.64353575893e-07
ko04921	Oxytocin signaling pathway	43/694	209/7206	1.12416085417e-06
ko04514	Cell adhesion molecules (CAMs)	31/694	130/7206	1.30870534083e-06
ko05031	Amphetamine addiction	24/694	91/7206	3.1722667112e-06
ko04010	MAPK signaling pathway	57/694	321/7206	3.9419979014e-06
ko04060	Cytokine-cytokine receptor interaction	3/694	191/7206	9.15076724622e-06
ko03040	Spliceosome	1/694	145/7206	1.13199704414e-05
ko04020	Calcium signaling pathway	48/694	265/7206	1.60376350061e-05
ko05203	Viral carcinogenesis	9/694	277/7206	6.40505899314e-05
ko04970	Salivary secretion	22/694	95/7206	7.25669682198e-05
ko03013	RNA transport	3/694	166/7206	8.51806703624e-05
ko05168	Herpes simplex infection	4/694	182/7206	0.000106805526753
ko04972	Pancreatic secretion	24/694	111/7206	0.000122986409858
ko04621	NOD-like receptor signaling pathway	3/694	157/7206	0.00017630548273
ko04720	Long-term potentiation	22/694	99/7206	0.000180427686444
ko05205	Proteoglycans in cancer	10/694	271/7206	0.000308407911434
ko04730	Long-term depression	18/694	78/7206	0.000338470735567
ko05322	Systemic lupus erythematosus	3/694	151/7206	0.000378539163664
ko05164	Influenza A	4/694	167/7206	0.000448549773449
ko04120	Ubiquitin mediated proteolysis	3/694	138/7206	0.00109793066309
ko04072	Phospholipase D signaling pathway	33/694	197/7206	0.00133913430911
ko04260	Cardiac muscle contraction	20/694	98/7206	0.00141809636801
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/694	79/7206	0.00146545232625
ko00240	Pyrimidine metabolism	2/694	110/7206	0.00177533044271
ko04915	Estrogen signaling pathway	24/694	131/7206	0.00232349730261
ko04350	TGF-beta signaling pathway	2/694	103/7206	0.00370087460001
ko03018	RNA degradation	1/694	84/7206	0.0042510138237
ko04022	cGMP-PKG signaling pathway	34/694	216/7206	0.00454751035009
ko04964	Proximal tubule bicarbonate reclamation	8/694	29/7206	0.00488102352779
ko05414	Dilated cardiomyopathy	20/694	112/7206	0.00561506558038
ko03008	Ribosome biogenesis in eukaryotes	1/694	79/7206	0.00610847286674
ko04540	Gap junction	22/694	128/7206	0.00614020337204
ko04217	Necroptosis	7/694	178/7206	0.00644726077907
ko00515	Mannose type O-glycan biosynthesis	7/694	25/7206	0.00763473472748
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/694	14/7206	0.00781040562195
ko05169	Epstein-Barr virus infection	9/694	206/7206	0.00784239477123
ko04971	Gastric acid secretion	18/694	98/7206	0.00831266695053
ko04924	Renin secretion	16/694	86/7206	0.00887669467702
ko01200	Carbon metabolism	4/694	128/7206	0.00920514169475
ko04146	Peroxisome	2/694	89/7206	0.0108270526653
ko04141	Protein processing in endoplasmic reticulum	8/694	184/7206	0.0108629181637
ko04214	Apoptosis - fly	1/694	72/7206	0.0136247638772
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/694	182/7206	0.0147071622301
ko04071	Sphingolipid signaling pathway	25/694	162/7206	0.015174049639
ko04640	Hematopoietic cell lineage	1/694	64/7206	0.0187924706224
ko04138	Autophagy - yeast	2/694	81/7206	0.0219608005296
ko00190	Oxidative phosphorylation	5/694	127/7206	0.0226520343305
ko04064	NF-kappa B signaling pathway	3/694	96/7206	0.0232016167213
ko05146	Amoebiasis	3/694	99/7206	0.0237861359968
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/694	59/7206	0.0259619759507
ko04015	Rap1 signaling pathway	38/694	278/7206	0.0286625818839
ko04612	Antigen processing and presentation	2/694	77/7206	0.0311705699153
ko04976	Bile secretion	14/694	80/7206	0.0328508283251
ko04740	Olfactory transduction	14/694	80/7206	0.0328508283251
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	6/694	26/7206	0.0337022874451
ko04930	Type II diabetes mellitus	10/694	54/7206	0.0354371569978
ko05410	Hypertrophic cardiomyopathy (HCM)	16/694	100/7206	0.0388715070726
ko05162	Measles	5/694	120/7206	0.0411036200921
ko00310	Lysine degradation	2/694	73/7206	0.0441245315965
ko05133	Pertussis	3/694	87/7206	0.0444503054637
ko00010	Glycolysis / Gluconeogenesis	2/694	74/7206	0.0446709561749
ko05140	Leishmaniasis	2/694	75/7206	0.0455258751303
ko04110	Cell cycle	7/694	145/7206	0.0460828456012
ko04923	Regulation of lipolysis in adipocytes	13/694	77/7206	0.0481581719965
ko02024	Quorum sensing	4/694	15/7206	0.0492545812962