ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 24/348 79/7206 1.18439186796e-13 ko04976 Bile secretion 23/348 80/7206 1.43700175821e-12 ko04974 Protein digestion and absorption 22/348 96/7206 5.79247728428e-10 ko00983 Drug metabolism - other enzymes 12/348 42/7206 3.96404491565e-07 ko00350 Tyrosine metabolism 10/348 33/7206 2.07350349605e-06 ko00643 Styrene degradation 4/348 4/7206 5.35042832711e-06 ko04614 Renin-angiotensin system 7/348 18/7206 1.15670249711e-05 ko04978 Mineral absorption 10/348 40/7206 1.40221893527e-05 ko04975 Fat digestion and absorption 9/348 35/7206 2.97672581886e-05 ko04977 Vitamin digestion and absorption 7/348 22/7206 5.23996298966e-05 ko02010 ABC transporters 9/348 39/7206 7.52620649143e-05 ko04972 Pancreatic secretion 16/348 111/7206 7.59668490077e-05 ko00380 Tryptophan metabolism 10/348 50/7206 0.000110327972643 ko00260 Glycine, serine and threonine metabolism 9/348 48/7206 0.000405409817918 ko03320 PPAR signaling pathway 11/348 69/7206 0.000416519527806 ko00140 Steroid hormone biosynthesis 8/348 41/7206 0.00064233770237 ko00830 Retinol metabolism 8/348 42/7206 0.000760705356831 ko05203 Viral carcinogenesis 3/348 277/7206 0.000896895990091 ko00360 Phenylalanine metabolism 5/348 17/7206 0.000975580265505 ko00232 Caffeine metabolism 3/348 5/7206 0.00103835332239 ko04744 Phototransduction 7/348 36/7206 0.00142961396865 ko04360 Axon guidance 2/348 233/7206 0.0015316817037 ko00982 Drug metabolism - cytochrome P450 7/348 37/7206 0.00169148175762 ko05204 Chemical carcinogenesis 8/348 48/7206 0.00188928636099 ko00120 Primary bile acid biosynthesis 5/348 20/7206 0.00216857689307 ko04964 Proximal tubule bicarbonate reclamation 6/348 29/7206 0.00224245084528 ko04310 Wnt signaling pathway 1/348 181/7206 0.0023119672826 ko04141 Protein processing in endoplasmic reticulum 1/348 184/7206 0.00240172805953 ko04010 MAPK signaling pathway 5/348 321/7206 0.00299768598906 ko05200 Pathways in cancer 11/348 492/7206 0.00317256453123 ko00591 Linoleic acid metabolism 5/348 22/7206 0.00340174780204 ko00770 Pantothenate and CoA biosynthesis 4/348 14/7206 0.00363785273721 ko04144 Endocytosis 6/348 342/7206 0.00407570476687 ko05010 Alzheimer's disease 2/348 202/7206 0.00434567841467 ko05169 Epstein-Barr virus infection 2/348 206/7206 0.00439609914468 ko03013 RNA transport 1/348 166/7206 0.00498135151663 ko00500 Starch and sucrose metabolism 6/348 35/7206 0.00600464332236 ko00340 Histidine metabolism 5/348 25/7206 0.00609359322883 ko05150 Staphylococcus aureus infection 6/348 36/7206 0.00691964919323 ko05012 Parkinson's disease 1/348 155/7206 0.00707077043193 ko00250 Alanine, aspartate and glutamate metabolism 6/348 38/7206 0.00904574989529 ko04110 Cell cycle 1/348 145/7206 0.010210663263 ko00980 Metabolism of xenobiotics by cytochrome P450 6/348 40/7206 0.0116021493372 ko04950 Maturity onset diabetes of the young 5/348 29/7206 0.0116315401687 ko00590 Arachidonic acid metabolism 7/348 52/7206 0.0118383744718 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 3/348 11/7206 0.013789780517 ko04740 Olfactory transduction 9/348 80/7206 0.0144827245039 ko04973 Carbohydrate digestion and absorption 6/348 42/7206 0.0146298488368 ko00480 Glutathione metabolism 7/348 55/7206 0.0158816657236 ko00100 Steroid biosynthesis 4/348 21/7206 0.0166569907886 ko05161 Hepatitis B 2/348 173/7206 0.0178397918676 ko05224 Breast cancer 2/348 174/7206 0.0180009390706 ko00053 Ascorbate and aldarate metabolism 4/348 22/7206 0.0196026003412 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/348 5/7206 0.0211035157179 ko00620 Pyruvate metabolism 6/348 46/7206 0.0222502285019 ko00640 Propanoate metabolism 5/348 34/7206 0.0224015790138 ko04722 Neurotrophin signaling pathway 2/348 160/7206 0.0246753472019 ko00410 beta-Alanine metabolism 5/348 35/7206 0.0251344016289 ko00362 Benzoate degradation 2/348 6/7206 0.0306540426042 ko04666 Fc gamma R-mediated phagocytosis 1/348 122/7206 0.0309797651404 ko00650 Butanoate metabolism 4/348 26/7206 0.0344605269097 ko04621 NOD-like receptor signaling pathway 2/348 157/7206 0.0354813182719 ko04932 Non-alcoholic fatty liver disease (NAFLD) 3/348 182/7206 0.0356131060115 ko04150 mTOR signaling pathway 3/348 184/7206 0.0356145317781 ko05152 Tuberculosis 3/348 187/7206 0.0360024900737 ko04146 Peroxisome 9/348 89/7206 0.039134759821 ko04920 Adipocytokine signaling pathway 9/348 89/7206 0.039134759821 ko04261 Adrenergic signaling in cardiomyocytes 4/348 205/7206 0.0471048372704 ko00520 Amino sugar and nucleotide sugar metabolism 6/348 55/7206 0.048127154859 ko00401 Novobiocin biosynthesis 1/348 1/7206 0.0482930890924 ko04217 Necroptosis 3/348 178/7206 0.0491822118862