ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	159/936	423/7206	1.94826880081e-40
ko04724	Glutamatergic synapse	82/936	152/7206	2.75723566087e-34
ko05033	Nicotine addiction	46/936	56/7206	6.12403920136e-32
ko04713	Circadian entrainment	69/936	136/7206	8.0480422648e-27
ko05032	Morphine addiction	61/936	110/7206	1.39081905844e-26
ko04727	GABAergic synapse	59/936	110/7206	1.01528642662e-24
ko04725	Cholinergic synapse	71/936	160/7206	4.08415679542e-23
ko04728	Dopaminergic synapse	76/936	185/7206	3.85503945016e-22
ko04723	Retrograde endocannabinoid signaling	73/936	175/7206	8.95983988471e-22
ko04721	Synaptic vesicle cycle	44/936	80/7206	2.72764765613e-19
ko04744	Phototransduction	28/936	36/7206	1.13322314947e-18
ko04024	cAMP signaling pathway	90/936	279/7206	1.73076184741e-17
ko04911	Insulin secretion	49/936	117/7206	4.64809680145e-15
ko04921	Oxytocin signaling pathway	68/936	209/7206	8.51933362241e-14
ko04726	Serotonergic synapse	51/936	137/7206	3.50997224911e-13
ko04742	Taste transduction	31/936	61/7206	1.00030086731e-12
ko04020	Calcium signaling pathway	76/936	265/7206	4.80832458409e-12
ko05031	Amphetamine addiction	37/936	91/7206	3.17957841791e-11
ko04261	Adrenergic signaling in cardiomyocytes	61/936	205/7206	1.26012700962e-10
ko04720	Long-term potentiation	38/936	99/7206	1.32378862027e-10
ko04740	Olfactory transduction	32/936	80/7206	1.13870382857e-09
ko04970	Salivary secretion	35/936	95/7206	2.60343635932e-09
ko04925	Aldosterone synthesis and secretion	36/936	105/7206	1.43162953548e-08
ko05030	Cocaine addiction	28/936	73/7206	3.7322167745e-08
ko03040	Spliceosome	1/936	145/7206	5.75471806877e-08
ko04971	Gastric acid secretion	33/936	98/7206	9.41864755184e-08
ko04060	Cytokine-cytokine receptor interaction	4/936	191/7206	1.46018833504e-07
ko05203	Viral carcinogenesis	11/936	277/7206	3.7162117556e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	26/936	74/7206	8.57827123411e-07
ko05168	Herpes simplex infection	6/936	182/7206	9.65263688787e-06
ko05164	Influenza A	5/936	167/7206	1.15981794738e-05
ko05322	Systemic lupus erythematosus	4/936	151/7206	1.32993412949e-05
ko04120	Ubiquitin mediated proteolysis	3/936	138/7206	1.53598053488e-05
ko04514	Cell adhesion molecules (CAMs)	35/936	130/7206	1.63366233411e-05
ko04972	Pancreatic secretion	31/936	111/7206	2.24546310727e-05
ko04745	Phototransduction - fly	15/936	38/7206	3.80085585019e-05
ko03013	RNA transport	6/936	166/7206	5.60758298738e-05
ko04010	MAPK signaling pathway	67/936	321/7206	5.71062978277e-05
ko04022	cGMP-PKG signaling pathway	49/936	216/7206	7.64315943736e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/936	79/7206	0.000128758876315
ko04621	NOD-like receptor signaling pathway	6/936	157/7206	0.000159256541248
ko04750	Inflammatory mediator regulation of TRP channels	31/936	122/7206	0.000182909670831
ko04966	Collecting duct acid secretion	11/936	26/7206	0.000201186124267
ko04072	Phospholipase D signaling pathway	44/936	197/7206	0.000225901599351
ko04610	Complement and coagulation cascades	1/936	79/7206	0.000317307468472
ko03008	Ribosome biogenesis in eukaryotes	1/936	79/7206	0.000317307468472
ko04260	Cardiac muscle contraction	26/936	98/7206	0.000359268193476
ko04540	Gap junction	31/936	128/7206	0.000460022471799
ko04612	Antigen processing and presentation	1/936	77/7206	0.000478167083041
ko05162	Measles	4/936	120/7206	0.000507824141001
ko04976	Bile secretion	22/936	80/7206	0.000567449968004
ko04915	Estrogen signaling pathway	31/936	131/7206	0.000861846667331
ko05110	Vibrio cholerae infection	18/936	63/7206	0.000934989947145
ko04730	Long-term depression	21/936	78/7206	0.000942599443844
ko05169	Epstein-Barr virus infection	12/936	206/7206	0.00102701906984
ko05161	Hepatitis B	9/936	173/7206	0.00119550694042
ko05414	Dilated cardiomyopathy	27/936	112/7206	0.00152395152393
ko04070	Phosphatidylinositol signaling system	27/936	112/7206	0.00152395152393
ko04110	Cell cycle	7/936	145/7206	0.00163829047651
ko04924	Renin secretion	22/936	86/7206	0.00170567501684
ko05166	HTLV-I infection	21/936	292/7206	0.00178029230748
ko04014	Ras signaling pathway	54/936	279/7206	0.00197184805813
ko05205	Proteoglycans in cancer	19/936	271/7206	0.00222512205317
ko04141	Protein processing in endoplasmic reticulum	11/936	184/7206	0.00255836659944
ko04360	Axon guidance	46/936	233/7206	0.00287736309821
ko05215	Prostate cancer	5/936	111/7206	0.00419250029737
ko05140	Leishmaniasis	2/936	75/7206	0.00480222304078
ko04626	Plant-pathogen interaction	7/936	18/7206	0.00528610002112
ko04923	Regulation of lipolysis in adipocytes	19/936	77/7206	0.00538298823086
ko04064	NF-kappa B signaling pathway	4/936	96/7206	0.00565235148745
ko04630	Jak-STAT signaling pathway	7/936	132/7206	0.00565551909022
ko04371	Apelin signaling pathway	36/936	177/7206	0.00615770295668
ko00520	Amino sugar and nucleotide sugar metabolism	1/936	55/7206	0.00773051358669
ko00480	Glutathione metabolism	1/936	55/7206	0.00773051358669
ko04964	Proximal tubule bicarbonate reclamation	9/936	29/7206	0.00897300023386
ko04350	TGF-beta signaling pathway	5/936	103/7206	0.0111681547239
ko00590	Arachidonic acid metabolism	1/936	52/7206	0.0114750440511
ko05016	Huntington's disease	16/936	215/7206	0.0130057039927
ko04640	Hematopoietic cell lineage	2/936	64/7206	0.0138638430087
ko04062	Chemokine signaling pathway	38/936	201/7206	0.0142877041231
ko04657	IL-17 signaling pathway	4/936	87/7206	0.0152762992107
ko04146	Peroxisome	4/936	89/7206	0.0158622028876
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/936	59/7206	0.0193483599894
ko04912	GnRH signaling pathway	25/936	122/7206	0.0198506843571
ko00330	Arginine and proline metabolism	2/936	61/7206	0.0199782489212
ko04214	Apoptosis - fly	3/936	72/7206	0.0209875309336
ko05206	MicroRNAs in cancer	13/936	177/7206	0.0229643918451
ko04930	Type II diabetes mellitus	13/936	54/7206	0.0232934748723
ko05144	Malaria	1/936	45/7206	0.0248050743996
ko00071	Fatty acid degradation	1/936	45/7206	0.0248050743996
ko03420	Nucleotide excision repair	1/936	46/7206	0.0251846310509
ko04140	Autophagy - animal	12/936	164/7206	0.0255218189503
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/936	14/7206	0.026693851937
ko05321	Inflammatory bowel disease (IBD)	2/936	56/7206	0.0283117389688
ko05217	Basal cell carcinoma	3/936	68/7206	0.0293243021509
ko04114	Oocyte meiosis	27/936	139/7206	0.0294938153241
ko04510	Focal adhesion	20/936	240/7206	0.0310590240751
ko04932	Non-alcoholic fatty liver disease (NAFLD)	14/936	182/7206	0.0330480341714
ko00680	Methane metabolism	9/936	34/7206	0.0346599514346
ko04918	Thyroid hormone synthesis	18/936	86/7206	0.0349696141096
ko00140	Steroid hormone biosynthesis	1/936	41/7206	0.0365614977666
ko05231	Choline metabolism in cancer	26/936	134/7206	0.0366115209762
ko03022	Basal transcription factors	1/936	44/7206	0.0385445680843
ko05034	Alcoholism	42/936	238/7206	0.0387535982089
ko00280	Valine, leucine and isoleucine degradation	2/936	54/7206	0.0404531543974
ko00240	Pyrimidine metabolism	7/936	110/7206	0.0436663922479
ko04550	Signaling pathways regulating pluripotency of stem cells	13/936	165/7206	0.04649982126
ko04658	Th1 and Th2 cell differentiation	6/936	96/7206	0.0466392703227
ko05410	Hypertrophic cardiomyopathy (HCM)	20/936	100/7206	0.0495032398959