ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 34/249 145/7206 1.18390978016e-19 ko04110 Cell cycle 30/249 145/7206 7.95575081015e-16 ko04111 Cell cycle - yeast 23/249 90/7206 1.77842569402e-14 ko03008 Ribosome biogenesis in eukaryotes 20/249 79/7206 1.18469744064e-12 ko03013 RNA transport 28/249 166/7206 1.68161291806e-12 ko04113 Meiosis - yeast 15/249 70/7206 1.03591831124e-08 ko03440 Homologous recombination 11/249 41/7206 8.48398513946e-08 ko03460 Fanconi anemia pathway 12/249 51/7206 1.06528300209e-07 ko04114 Oocyte meiosis 17/249 139/7206 5.19546022248e-06 ko00240 Pyrimidine metabolism 14/249 110/7206 2.27837412803e-05 ko03015 mRNA surveillance pathway 12/249 93/7206 7.69251597563e-05 ko04144 Endocytosis 1/249 342/7206 0.000106493224067 ko05166 HTLV-I infection 23/249 292/7206 0.00020297675171 ko03410 Base excision repair 7/249 38/7206 0.000272483250127 ko03020 RNA polymerase 6/249 29/7206 0.000389754611479 ko04914 Progesterone-mediated oocyte maturation 11/249 104/7206 0.000874224609153 ko04020 Calcium signaling pathway 1/249 265/7206 0.00161953066572 ko03030 DNA replication 6/249 38/7206 0.00174618650261 ko03018 RNA degradation 9/249 84/7206 0.00232949432532 ko04120 Ubiquitin mediated proteolysis 12/249 138/7206 0.00284605875929 ko03022 Basal transcription factors 6/249 44/7206 0.00375704747036 ko05203 Viral carcinogenesis 19/249 277/7206 0.00380558380676 ko04115 p53 signaling pathway 8/249 74/7206 0.0038136216921 ko03420 Nucleotide excision repair 6/249 46/7206 0.00470725956295 ko04810 Regulation of actin cytoskeleton 2/249 264/7206 0.00898540610586 ko05010 Alzheimer's disease 1/249 202/7206 0.0104378154132 ko04261 Adrenergic signaling in cardiomyocytes 1/249 205/7206 0.0104819891028 ko04060 Cytokine-cytokine receptor interaction 1/249 191/7206 0.0151060098747 ko04072 Phospholipase D signaling pathway 1/249 197/7206 0.0154730342246 ko04218 Cellular senescence 12/249 177/7206 0.0211940674477 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/249 182/7206 0.0219245144799 ko04728 Dopaminergic synapse 1/249 185/7206 0.0222715013746 ko05152 Tuberculosis 1/249 187/7206 0.0226340941695 ko04530 Tight junction 2/249 228/7206 0.0252360454872 ko04010 MAPK signaling pathway 4/249 321/7206 0.0266922855349 ko04151 PI3K-Akt signaling pathway 6/249 390/7206 0.0313609248518 ko05169 Epstein-Barr virus infection 13/249 206/7206 0.0314503014749 ko04723 Retrograde endocannabinoid signaling 1/249 175/7206 0.0324727467982 ko04022 cGMP-PKG signaling pathway 2/249 216/7206 0.0353711907071 ko03430 Mismatch repair 3/249 22/7206 0.0386528510456 ko00310 Lysine degradation 6/249 73/7206 0.0397463923059 ko05012 Parkinson's disease 1/249 155/7206 0.0451604517581 ko04145 Phagosome 1/249 162/7206 0.0461572602591