ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04721	Synaptic vesicle cycle	35/503	80/7206	3.34844517093e-20
ko04724	Glutamatergic synapse	46/503	152/7206	1.95206634935e-18
ko04080	Neuroactive ligand-receptor interaction	80/503	423/7206	2.47216870208e-17
ko04728	Dopaminergic synapse	48/503	185/7206	3.43127758192e-16
ko04727	GABAergic synapse	36/503	110/7206	7.25430764436e-16
ko05033	Nicotine addiction	24/503	56/7206	5.58060228445e-14
ko05032	Morphine addiction	32/503	110/7206	1.22750121668e-12
ko04723	Retrograde endocannabinoid signaling	40/503	175/7206	9.52192993391e-12
ko04713	Circadian entrainment	34/503	136/7206	2.64288886965e-11
ko04725	Cholinergic synapse	36/503	160/7206	1.74684457745e-10
ko04966	Collecting duct acid secretion	14/503	26/7206	2.42092859237e-10
ko04911	Insulin secretion	29/503	117/7206	9.92521806826e-10
ko05031	Amphetamine addiction	25/503	91/7206	1.44169008239e-09
ko05030	Cocaine addiction	22/503	73/7206	2.08995265646e-09
ko04726	Serotonergic synapse	30/503	137/7206	1.19008562801e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	20/503	74/7206	8.77339612696e-08
ko05110	Vibrio cholerae infection	18/503	63/7206	1.54777442673e-07
ko05120	Epithelial cell signaling in Helicobacter pylori infection	22/503	92/7206	2.14511466828e-07
ko04720	Long-term potentiation	22/503	99/7206	8.36400018113e-07
ko04261	Adrenergic signaling in cardiomyocytes	32/503	205/7206	1.68353090474e-05
ko00190	Oxidative phosphorylation	23/503	127/7206	1.85834285571e-05
ko04921	Oxytocin signaling pathway	32/503	209/7206	2.16147097082e-05
ko04145	Phagosome	27/503	162/7206	2.44561571245e-05
ko04024	cAMP signaling pathway	39/503	279/7206	3.23125923953e-05
ko05168	Herpes simplex infection	1/503	182/7206	4.47608684998e-05
ko04970	Salivary secretion	18/503	95/7206	8.13727963963e-05
ko05010	Alzheimer's disease	29/503	202/7206	0.00019452475028
ko04060	Cytokine-cytokine receptor interaction	2/503	191/7206	0.000232083055275
ko05323	Rheumatoid arthritis	16/503	89/7206	0.000375775214718
ko04744	Phototransduction	9/503	36/7206	0.00062787900273
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/503	59/7206	0.000637181198241
ko05034	Alcoholism	31/503	238/7206	0.000652399853127
ko04514	Cell adhesion molecules (CAMs)	20/503	130/7206	0.000703328685225
ko03040	Spliceosome	1/503	145/7206	0.000717851074397
ko04626	Plant-pathogen interaction	6/503	18/7206	0.00100975048359
ko04260	Cardiac muscle contraction	16/503	98/7206	0.00112545933897
ko04540	Gap junction	19/503	128/7206	0.00141126056164
ko04962	Vasopressin-regulated water reabsorption	11/503	58/7206	0.00193698571054
ko04010	MAPK signaling pathway	37/503	321/7206	0.00227974092457
ko04924	Renin secretion	14/503	86/7206	0.00231927984848
ko04022	cGMP-PKG signaling pathway	27/503	216/7206	0.00263672512622
ko04730	Long-term depression	13/503	78/7206	0.00265199810157
ko04925	Aldosterone synthesis and secretion	16/503	105/7206	0.00283725800359
ko05162	Measles	1/503	120/7206	0.00315508379961
ko04971	Gastric acid secretion	15/503	98/7206	0.00385112168571
ko04745	Phototransduction - fly	8/503	38/7206	0.00403178519461
ko05166	HTLV-I infection	9/503	292/7206	0.00472832260285
ko05164	Influenza A	3/503	167/7206	0.0049280423013
ko04742	Taste transduction	10/503	61/7206	0.00896539284806
ko04020	Calcium signaling pathway	30/503	265/7206	0.00920723120436
ko05322	Systemic lupus erythematosus	3/503	151/7206	0.00928355540242
ko04510	Focal adhesion	7/503	240/7206	0.00934841518393
ko05206	MicroRNAs in cancer	4/503	177/7206	0.010062894886
ko04972	Pancreatic secretion	15/503	111/7206	0.0127688376771
ko04110	Cell cycle	3/503	145/7206	0.0129335254758
ko03013	RNA transport	4/503	166/7206	0.0133584216652
ko04964	Proximal tubule bicarbonate reclamation	6/503	29/7206	0.013417790389
ko04371	Apelin signaling pathway	21/503	177/7206	0.0157509001995
ko04360	Axon guidance	26/503	233/7206	0.0175957321695
ko04120	Ubiquitin mediated proteolysis	3/503	138/7206	0.01797120668
ko04146	Peroxisome	1/503	89/7206	0.0202921548235
ko04922	Glucagon signaling pathway	16/503	128/7206	0.0211255668522
ko04912	GnRH signaling pathway	15/503	122/7206	0.0294209096724
ko04014	Ras signaling pathway	29/503	279/7206	0.0300458145329
ko04657	IL-17 signaling pathway	1/503	87/7206	0.0306024873767
ko05224	Breast cancer	5/503	174/7206	0.033131796282
ko05167	Kaposi's sarcoma-associated herpesvirus infection	21/503	191/7206	0.0418971023531
ko04114	Oocyte meiosis	16/503	139/7206	0.0424399817383
ko00512	Mucin type O-glycan biosynthesis	5/503	29/7206	0.0479129150887