ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	119/613	423/7206	7.40273865086e-35
ko05033	Nicotine addiction	40/613	56/7206	5.34210533179e-31
ko04724	Glutamatergic synapse	65/613	152/7206	8.41246654937e-31
ko04727	GABAergic synapse	46/613	110/7206	1.53895948476e-21
ko04728	Dopaminergic synapse	59/613	185/7206	2.72040028984e-20
ko04713	Circadian entrainment	49/613	136/7206	1.50860142795e-19
ko05032	Morphine addiction	43/613	110/7206	7.48772994145e-19
ko04723	Retrograde endocannabinoid signaling	55/613	175/7206	1.20477813421e-18
ko05030	Cocaine addiction	30/613	73/7206	3.3191569435e-14
ko04911	Insulin secretion	38/613	117/7206	9.84288474217e-14
ko05031	Amphetamine addiction	33/613	91/7206	1.23702582539e-13
ko04024	cAMP signaling pathway	63/613	279/7206	1.78098250386e-13
ko04261	Adrenergic signaling in cardiomyocytes	48/613	205/7206	4.15062072036e-11
ko04720	Long-term potentiation	31/613	99/7206	5.70163244834e-11
ko04725	Cholinergic synapse	40/613	160/7206	2.27240653776e-10
ko04020	Calcium signaling pathway	55/613	265/7206	2.56790256856e-10
ko04721	Synaptic vesicle cycle	26/613	80/7206	8.36859371121e-10
ko04742	Taste transduction	22/613	61/7206	1.82556102564e-09
ko04921	Oxytocin signaling pathway	45/613	209/7206	3.10962867814e-09
ko05014	Amyotrophic lateral sclerosis (ALS)	24/613	74/7206	3.95333362713e-09
ko04726	Serotonergic synapse	34/613	137/7206	6.48301062506e-09
ko04010	MAPK signaling pathway	59/613	321/7206	7.81460013386e-09
ko04970	Salivary secretion	25/613	95/7206	1.9958918254e-07
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/613	79/7206	3.72046745383e-07
ko04514	Cell adhesion molecules (CAMs)	28/613	130/7206	3.13253381386e-06
ko04972	Pancreatic secretion	25/613	111/7206	4.55036186543e-06
ko04971	Gastric acid secretion	23/613	98/7206	5.24597078901e-06
ko05414	Dilated cardiomyopathy	25/613	112/7206	5.39823147156e-06
ko04360	Axon guidance	41/613	233/7206	6.21971658117e-06
ko04260	Cardiac muscle contraction	22/613	98/7206	1.79014627391e-05
ko04730	Long-term depression	19/613	78/7206	1.96194210359e-05
ko03040	Spliceosome	1/613	145/7206	6.01526358891e-05
ko05203	Viral carcinogenesis	7/613	277/7206	6.07924501177e-05
ko04540	Gap junction	25/613	128/7206	7.10384418279e-05
ko04915	Estrogen signaling pathway	25/613	131/7206	9.81278060879e-05
ko03013	RNA transport	2/613	166/7206	9.9797600879e-05
ko04072	Phospholipase D signaling pathway	33/613	197/7206	0.000134580888077
ko04925	Aldosterone synthesis and secretion	21/613	105/7206	0.00024652415564
ko05034	Alcoholism	36/613	238/7206	0.000550057163245
ko05168	Herpes simplex infection	4/613	182/7206	0.000652618734862
ko04022	cGMP-PKG signaling pathway	33/613	216/7206	0.000761577631221
ko05410	Hypertrophic cardiomyopathy (HCM)	19/613	100/7206	0.000782406959932
ko04621	NOD-like receptor signaling pathway	3/613	157/7206	0.0011850603231
ko04630	Jak-STAT signaling pathway	2/613	132/7206	0.00132429727942
ko04142	Lysosome	3/613	151/7206	0.00163637398478
ko05164	Influenza A	4/613	167/7206	0.00180191919449
ko05169	Epstein-Barr virus infection	6/613	206/7206	0.00206859664859
ko04110	Cell cycle	3/613	145/7206	0.00227691928491
ko04924	Renin secretion	16/613	86/7206	0.00259585076539
ko04740	Olfactory transduction	15/613	80/7206	0.00347280079107
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/613	59/7206	0.00349314355057
ko05322	Systemic lupus erythematosus	4/613	151/7206	0.00486730925663
ko05205	Proteoglycans in cancer	11/613	271/7206	0.00526337909686
ko00240	Pyrimidine metabolism	2/613	110/7206	0.00552839659195
ko04146	Peroxisome	1/613	89/7206	0.00634287889389
ko04140	Autophagy - animal	5/613	164/7206	0.00688746196021
ko04141	Protein processing in endoplasmic reticulum	6/613	184/7206	0.00689151021888
ko04976	Bile secretion	14/613	80/7206	0.0077511012854
ko04912	GnRH signaling pathway	19/613	122/7206	0.00831036510462
ko00190	Oxidative phosphorylation	3/613	127/7206	0.00912737490177
ko03018	RNA degradation	1/613	84/7206	0.0092355423332
ko04217	Necroptosis	6/613	178/7206	0.00924656050762
ko05231	Choline metabolism in cancer	20/613	134/7206	0.0116451813915
ko05162	Measles	3/613	120/7206	0.012420310456
ko03008	Ribosome biogenesis in eukaryotes	1/613	79/7206	0.0134365192645
ko04150	mTOR signaling pathway	7/613	184/7206	0.0157618585884
ko00515	Mannose type O-glycan biosynthesis	6/613	25/7206	0.0161309888249
ko01524	Platinum drug resistance	1/613	76/7206	0.0201821854271
ko04612	Antigen processing and presentation	1/613	77/7206	0.0207409677709
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/613	182/7206	0.02110490846
ko04930	Type II diabetes mellitus	10/613	54/7206	0.022414872797
ko04015	Rap1 signaling pathway	34/613	278/7206	0.0279954767051
ko03320	PPAR signaling pathway	1/613	69/7206	0.0283443389191
ko04962	Vasopressin-regulated water reabsorption	10/613	58/7206	0.0286898057179
ko04214	Apoptosis - fly	1/613	72/7206	0.0298980522504
ko00512	Mucin type O-glycan biosynthesis	6/613	29/7206	0.0324135281879
ko05222	Small cell lung cancer	2/613	89/7206	0.0327514778422
ko04923	Regulation of lipolysis in adipocytes	12/613	77/7206	0.0367797770724
ko00600	Sphingolipid metabolism	1/613	63/7206	0.0409981062231
ko04120	Ubiquitin mediated proteolysis	5/613	138/7206	0.0430174501384
ko04138	Autophagy - yeast	2/613	81/7206	0.0450406602384
ko04750	Inflammatory mediator regulation of TRP channels	17/613	122/7206	0.0467783192895
ko04666	Fc gamma R-mediated phagocytosis	17/613	122/7206	0.0467783192895
ko04068	FoxO signaling pathway	7/613	167/7206	0.0477717474086
ko04918	Thyroid hormone synthesis	13/613	86/7206	0.0478360231527
ko04940	Type I diabetes mellitus	6/613	32/7206	0.049877717054