ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04721	Synaptic vesicle cycle	32/443	80/7206	8.26670810135e-19
ko05033	Nicotine addiction	25/443	56/7206	2.54923243815e-16
ko04724	Glutamatergic synapse	36/443	152/7206	8.63725220537e-13
ko04727	GABAergic synapse	30/443	110/7206	1.50436919687e-12
ko05032	Morphine addiction	29/443	110/7206	9.07646359141e-12
ko04728	Dopaminergic synapse	38/443	185/7206	2.10526666679e-11
ko04080	Neuroactive ligand-receptor interaction	62/443	423/7206	8.09706406968e-11
ko04723	Retrograde endocannabinoid signaling	33/443	175/7206	4.6904505429e-09
ko04713	Circadian entrainment	28/443	136/7206	9.6247147182e-09
ko04514	Cell adhesion molecules (CAMs)	27/443	130/7206	1.46151016194e-08
ko04725	Cholinergic synapse	30/443	160/7206	2.76509226955e-08
ko04024	cAMP signaling pathway	41/443	279/7206	1.31773048107e-07
ko05030	Cocaine addiction	17/443	73/7206	1.3518569967e-06
ko05203	Viral carcinogenesis	2/443	277/7206	5.24120054166e-06
ko04911	Insulin secretion	21/443	117/7206	7.18917997233e-06
ko04261	Adrenergic signaling in cardiomyocytes	30/443	205/7206	8.66892486944e-06
ko04010	MAPK signaling pathway	40/443	321/7206	1.37888820841e-05
ko04966	Collecting duct acid secretion	9/443	26/7206	1.41083403678e-05
ko05110	Vibrio cholerae infection	14/443	63/7206	2.07013070957e-05
ko04726	Serotonergic synapse	22/443	137/7206	2.74388245817e-05
ko04921	Oxytocin signaling pathway	29/443	209/7206	2.88196884943e-05
ko05205	Proteoglycans in cancer	3/443	271/7206	4.95864473854e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/443	14/7206	0.000102571895267
ko04360	Axon guidance	30/443	233/7206	0.000125055828338
ko05014	Amyotrophic lateral sclerosis (ALS)	13/443	74/7206	0.000498790103482
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	13/443	79/7206	0.000949906984358
ko05120	Epithelial cell signaling in Helicobacter pylori infection	14/443	92/7206	0.0013543772364
ko05322	Systemic lupus erythematosus	1/443	151/7206	0.00157360463939
ko04970	Salivary secretion	14/443	95/7206	0.00185612462084
ko03040	Spliceosome	1/443	145/7206	0.00232386398353
ko04260	Cardiac muscle contraction	14/443	98/7206	0.00250334324443
ko05323	Rheumatoid arthritis	13/443	89/7206	0.00289065124906
ko05164	Influenza A	2/443	167/7206	0.00294584242297
ko05031	Amphetamine addiction	13/443	91/7206	0.00352515813037
ko01200	Carbon metabolism	1/443	128/7206	0.00467427507209
ko05169	Epstein-Barr virus infection	4/443	206/7206	0.00732968451425
ko04022	cGMP-PKG signaling pathway	23/443	216/7206	0.00896886794217
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/443	59/7206	0.00931728123115
ko04742	Taste transduction	9/443	61/7206	0.0115414295508
ko04145	Phagosome	18/443	162/7206	0.0124621526463
ko04140	Autophagy - animal	3/443	164/7206	0.0132058798418
ko03013	RNA transport	3/443	166/7206	0.0132610780456
ko00240	Pyrimidine metabolism	1/443	110/7206	0.0145319452901
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/443	182/7206	0.0185981800925
ko04014	Ras signaling pathway	27/443	279/7206	0.0209886505073
ko04962	Vasopressin-regulated water reabsorption	8/443	58/7206	0.0244761502545
ko04972	Pancreatic secretion	13/443	111/7206	0.0251057170184
ko04730	Long-term depression	10/443	78/7206	0.0273336137572
ko04071	Sphingolipid signaling pathway	17/443	162/7206	0.0294664910707
ko04964	Proximal tubule bicarbonate reclamation	5/443	29/7206	0.0299657432822
ko05162	Measles	2/443	120/7206	0.0338195711604
ko04211	Longevity regulating pathway	2/443	123/7206	0.0345177229865
ko04915	Estrogen signaling pathway	14/443	131/7206	0.0406594021286
ko05016	Huntington's disease	6/443	215/7206	0.0416820928208
ko04146	Peroxisome	1/443	89/7206	0.0434003587229
ko04940	Type I diabetes mellitus	5/443	32/7206	0.0437555021079
ko04120	Ubiquitin mediated proteolysis	3/443	138/7206	0.047823806179
ko04072	Phospholipase D signaling pathway	19/443	197/7206	0.0487611184593